★ The Hidden Poison Turning Your Blood Against You
★ TOP STORY
The Hidden Poison Turning Your Blood Against You
You won’t see it, smell it, or taste it - but it’s inside nearly everyone. Researchers have traced a silent trigger that makes blood clot out of nowhere, even in the healthy. It starts in your gut, spreads through your veins, and ends in the headlines no one connects.
Advertisement
Unlock Benefits Beyond Your Gut with Premium Probiotics
Gut health not only affects your digestive system but your immune, heart, and brain health as well. Our potent, multi-strain Complete Probiotics formula utilizes patented delayed-release capsules for protection against harsh stomach acids, delivering the 10 probiotic strains directly to your small intestine where they work best.
📈 TRENDING NEWS
How’s Your Pancreas? Subtle Signs of Problems You Should Not Ignore
Your pancreas works quietly behind the scenes to digest your food and balance your blood sugar - until it starts to fail. Subtle signs like greasy stools, fatigue after meals, or back pain could be your body’s early warning that this organ needs urgent attention.
Is Paternal Age an Issue in Reproductive Planning?
New research shows that men, like women, experience age-related changes in fertility, as ‘selfish’ sperm mutations build up over time and reshape the genetic health of future generations.
🔥 HOT
Breaking News: What You Need to Know
Up-to-date info on the latest health-related news happening in the world.
Advertisement
Colostrum from New Zealand’s Gold Standard Dairies
Fuel your body with clean, nutrient-rich colostrum straight from New Zealand. Power up immunity, support digestion, and feel naturally energized. Today only - because better health shouldn’t wait. Shop now and start feeling the difference!
Disclaimer: The entire contents of this website are based upon the opinions of Dr. Mercola, unless otherwise noted. Individual articles are based upon the opinions of the respective author, who retains copyright as marked. The information on this website is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice. It is intended as a sharing of knowledge and information from the research and experience of Dr. Mercola and his community. Dr. Mercola encourages you to make your own health care decisions based upon your research and in partnership with a qualified health care professional.
Mercola.com, 125 SW 3rd Place, Suite 205, Cape Coral, FL 33991
US Number: (877) 985-2695 | Intl Number: 1 (239) 599-9500
© 1997-2025 Dr. Joseph Mercola. All Rights Reserved.
*These statements have not been evaluated by the Food and Drug Administration.
These products are not intended to diagnose, treat, cure, or prevent any disease.
A diet that avoids promoting endotoxins is linked to metabolic diseases, including cardiovascular, neurodegenerative, and cancerous diseases. Excessive intake of fructose and linoleic acid in the typical human diet is associated with a global increase in metabolic disorders. Chronic endotoxemia commonly occurs in obesity and is a major factor inducing systemic inflammation that leads to metabolic syndrome. Healthy dietary choices, such as consuming fish, fresh vegetables, and fruits and berries, can be associated with positive health outcomes by reducing systemic endotoxemia. Vitamin D restriction and/or a high-fat diet increases the risk of metabolic endotoxemia. Phytochemicals reduce endotoxins.
Specific components of the Western diet, such as PUFAs, monosaccharides, processed fats, gluten, alcohol, and additives, can affect the tight junctions between enterocytes, leading to increased permeability and the translocation of endotoxins into the bloodstream. These endotoxins include lipopolysaccharides derived from gram-negative bacteria.
In particular, a high-fructose diet can increase intestinal permeability and circulating endotoxins by altering intestinal barrier function and microbial composition. Excess fructose causes inflammation and de novo lipogenesis, which leads to hepatic steatosis, thus causing abdominal adiposity and insulin resistance.
Serum endotoxin levels are elevated in patients with liver cirrhosis, diabetes, cardiovascular disease, chronic infections, aging, amyotrophic lateral sclerosis, and Alzheimer's disease. The highest plasma endotoxin levels are found in patients with sepsis, around 500 pg/ml.
Endotoxin levels in blood plasma are normally low, but they rise during infections, intestinal inflammation, gum disease, and neurodegenerative diseases. Leaky gut leads to the release of bacterial metabolites and endotoxins, such as lipopolysaccharide, into the bloodstream, causing bacterial infections and oxidative stress. A diet rich in polyunsaturated fats, exposure to alcohol or chronic allergens, and dysbiosis are strongly associated with the development and/or progression of various systemic metabolic and autoimmune diseases, neurodegenerative disease, cardiovascular disease, inflammatory bowel disease, cancer, and the development of metastases.
Increases in blood endotoxin levels have been associated with increases in C-reactive protein concentrations and increases in intestinal permeability markers such as zonulite. Probiotics help modify the gut microbiota, promote the growth of beneficial bacteria, and are an alternative source of short-chain fatty acids (SCFAs). They also reduce LPS expression, intestinal inflammation, and tumor size in colorectal cancer (CRC). Among them, Akkermansia muciniphila has the ability to reduce LPS expression, improving metabolic endotoxemia.
https://www.mdpi.com/2076-2607/11/2/267 (2023).--
https://www.sciencedirect.com/science/article/pii/S002231662304525X (2023).-
https://www.mdpi.com/2304-8158/12/19/3706 (2023).-
https://www.cghjournal.org/article/S1542-3565(22)01110-7/fulltext (2023).-
https://www.mdpi.com/2076-2607/11/2/267 (2023).-
https://www.sciencedirect.com/science/article/pii/S002231662304525X (2023)
https://www.mdpi.com/2304-8158/12/19/3706 (2023).-
https://www.sciencedirect.com/science/article/pii/S2405844023061042 (2023).-
https://link.springer.com/article/10.1007/s11739-023-03374-w (2024).--
https://onlinelibrary.wiley.com/doi/full/10.1111/eci.14224 (2024).---
https://www.cell.com/trends/endocrinology-metabolism/abstract/S1043-2760(24)00087-0 (2024).—
https://ejhm.journals.ekb.eg/article_349082.html (2024).--
Our bodies are designed to be healthy if given a chance. One of it's systems first formed starts from our mouths to the other end with the Gut in-between. A healthy gut is our foundational, one of the first and most important. Obviously, the very first is being able to breath, followed by a need for proper and sanitary water, but, quickly followed by solid, basic nutritional needs supporting the Gut and the Microbes we have a symbiotic relationship with. The Mitochondria at some point moved directly inside the cells of our bodies, those in the gut are outside as far as Mitochondria are concerned, but as crucial to feed our cells and the Mitochondria supporting the prevention of Dis-Ease. Along with this is the "Gut Health" of our Garden, Planet Earth and the needs of proper care and support so it in turn can "feed" the whole of Life in the Garden. So much of our food production, foods sources are coming from toxic, life disruption compounds we're told geared to "Efficiency" - (the lowest number of workers needed, the most amounts of profit's for the fewest individuals???) is the only way, again, "We" can feed the world. Healing the Garden from the top down does not seem to be coming anytime soon, so it would seem the way back to health would come from the bottom up. Locally. Keep it Local Keep it Real...Support Biodynamic, Regenerative, Sustainable Agriculture living as much as possible. Producing real life sustaining, nourishing food heals not only our Guts, but the "Gut" of our Garden, Planet Earth.