Dr. Patrick Soon-Shiong discusses rising cancer rates in younger people, COVID-19's role in inflammation, and how to boost natural killer cells for immunity.
We have a pharmaceutical industry that prioritizes profits over people's health. Chemotherapy is very aggressive and weakens people's immune systems, jeopardizing their health. The truth is that when a person has cancer, they also develop cancer stem cells (CSCs) that are resistant to chemotherapy, although immunotherapy can, in some cases, help fight these stem cells by boosting each person's natural killer (NK) cells. However, it is prescribed less frequently due to its higher cost and side effects. NK cells, or Natural Killer cells, are immune cells with small particles containing enzymes capable of eliminating tumor cells or cells infected by a virus.
Recent studies lead us to believe that increasing the production of NK cells will enhance immune defense responses to eliminate cancerous or infected cells and improve overall health. For example, the use of probiotics has shown results of potentially increasing NK cell counts.
My doctoral thesis advisor had prostate cancer and, after six years, developed bone metastases. I know many other similar cases. A friend of my wife had stage 3 lung cancer and was treated with chemotherapy and immunotherapy. She then had a CT scan and appeared cured. However, she developed metastasis a few years later.
Other colleagues with advanced stomach and colon cancer also developed metastasis within a few years. I only know one friend with stage 2 colon cancer, without lymph node involvement, who did not undergo chemotherapy and is still alive after more than 5 years.
Many articles state that foods and supplements attack cancer stem cells.
The theory that cancer stem cells (CSCs) initiate and sustain various carcinogenic processes has been validated, and specific methods for identifying CSCs within the entire cancer cell population have also been shown to be effective. Studies provide an overview of recently acquired scientific knowledge regarding phytochemicals and herbal extracts, which have been shown to be capable of targeting and killing CSCs. Many genes and proteins that support the self-renewal capacity of CSCs and drug resistance have been described, and applications of phytochemicals capable of interfering with these signaling systems have been shown to be operationally efficient both in vitro and in vivo. The identification of specific surface antigens, mammosphere formation assays, serial colony-forming unit assays, xenograft transplantation, and tag retention assays, along with the evaluation of aldehyde dehydrogenase 1 (ALDH1) activity, are the most widely used techniques to measure phytochemical efficiency in CSC destruction.
Among chemopreventive dietary agents, the following are the most effective at reducing the proliferative activity of cancer cell lines: the polyphenol epigallocatechin-3-gallate (EGCG), curcumin, resveratrol, lycopene, pomegranate extracts, luteolin, genistein, piperine, β-carotene, and sulforaphane. These phytochemicals have been extensively studied for at least three decades. In fact, research on phytochemicals began even before the potential role of cancer cell lines (CSCs) in tumor development and spread was known. However, these studies provide a wealth of knowledge that can now be applied to the development of treatments against CSCs. Examples of these compounds are reported below.
EGCG, curcumin, piperine, sulforaphane, β-carotene, genistein, and whole extracts of some plants have been shown to be capable of killing CSCs. Most of these phytochemicals act by interfering with the canonical Wnt pathway (β-catenin/T-cell factor-lymphoid enhancer factor (TCF-LEF)) involved in the pathogenesis of several types of cancer. Therefore, the use of phytochemicals may be a true therapeutic strategy for eradicating cancer by eliminating cancer stem cells (CSCs).
EGCG is the most abundant polyphenol in green tea. It is capable of inducing caspase 8-dependent apoptosis in tumor cell cultures and animal models. Several clinical trials are underway involving EGCG alone or in combination with cisplatin and oxaliplatin due to EGCG's ability to synergistically increase the efficacy of these conventional drugs against prostate carcinoma and colorectal cancer.
Curcumin has been shown to disrupt the carcinogenic process by inhibiting the initiation step or suppressing the promotion and progression stages in animal models. Curcumin has also been reported to exhibit synergistic chemopreventive effects with other dietary polyphenols, such as genistein, EGCG, and embelin, and to enhance the efficacy of many cancer drugs, including 5-fluorouracil, vinca alkaloid, vinorelbine, cisplatin, and gemcitabine. It is important to highlight the significant role that various phytochemicals and bioactive compounds play in stimulating our immune system. Flavonoids are among the broad group of phenolic substances that possess antioxidant, anticancer, antimicrobial, cytotoxic, and antimutagenic properties. Consuming polyphenols (such as flavonoid-3-ols, procyanidins, catechins, flavones, resveratrol, anthocyanidins, and flavanones) can help maintain a healthy balance.
Fisetin, quercetin, apigenin, sulforaphane, and berberine are effective natural senolytics capable of activating autophagy (the mechanism for eliminating toxic elements stored in cells) and thus combating cancer. Everyday foods such as tea, onions, apples, and cucumbers contain fisetin, a flavonoid very similar to quercetin. According to experiments conducted by researchers at the American Scripps Research Institute, fisetin may prolong life. Apigenin is a compound found in vegetables and fruits that, according to a recently published laboratory study, weakens cancer cells, transforming them into normal, mortal cells. This compound is present in parsley, celery, and chamomile and weakens cancer cells. The links provide details of the phytochemicals present in food that attack cancer stem cells. Table 2 offers a brief summary of those capable of killing cancer stem cells, indicating the molecular mechanism involved in their action and the cellular marker. demonstrates its effect.
Numerous studies have documented the antineoplastic properties of fungi, derived from two main sources: high-molecular-weight cell wall components (polysaccharides and proteoglycans) and low-molecular-weight secondary metabolites (terpenes, phenolic compounds, etc.). The primary anticancer mechanism is indirect and immunological, driven by polysaccharides and proteoglycans. These compounds act as immunomodulators, binding to pattern recognition receptors such as Dectin-1 and TLR2/4 on intestinal immune cells. This triggers a systemic cascade that enhances both innate and adaptive immunity. It promotes dendritic cell maturation, regulates the polarization of macrophages and helper T lymphocytes, increases natural killer (NK) cell populations, and elevates levels of key cytokines, such as IFN-γ, TNF-α, and IL-12. Although immune enhancement is well established, the potential involvement of complement receptor 3 (CR3) in fungal-mediated cytotoxicity, a critical pathway in therapy-induced cell death, remains an open and clinically significant question.
Unlike high-molecular-weight cell wall components, the direct anticancer activities of fungi are primarily due to a set of low-molecular-weight compounds (secondary metabolites). These compounds inhibit key signaling pathways and affect different characteristics of malignant cells. The potential synergy between high-molecular-weight cell wall components (polysaccharides and proteoglycans) and low-molecular-weight secondary metabolites, which combine immunomodulation with direct cytotoxicity, is a key area for preclinical research, particularly with "double" extracts that combine both. Furthermore, specific fungal immunomodulatory proteins (FIPs, such as LZ-8 and GMI) directly affect cancer cell signaling and represent promising adjuvants.
Some studies involve the regulation of pathway mechanisms, including the PI3K/AKT, EGFR/Raf, mTOR/AMPK, P53, Dectin-1/Syk/NF-κB, and TLR4/NF/κB signaling pathways. Furthermore, the mechanisms by which these compounds exert anticancer and immunomodulatory effects suggest that, in the future, these fungi, or their bioactive components, could be developed as drugs for targeted cancer therapies. Therefore, fungi present a valuable dual role as both food sources and potential therapeutic agents.
y said, just to say that treatments don't affect outcomes is because there no designed to affect outcomes. Infact they are designed to cement the evental return, and enhancing the profit to the treatment industry or healthcare establishment, however you prefer to call it/them.
There is also an effective and scientifically supported anticancer supplement. Researchers at the Faculty of Pharmaceutical Sciences of the University of Tokyo developed Active Hexose Correlated Compound (AHCC) in 1987. Since then, AHCC has been the subject of more than 200 clinical studies, both in vitro and in vivo in humans and animals, primarily conducted in Japan.
Currently, more than 150 research projects are underway in laboratories and university hospitals in Japan and the United States, and each year more than 300 physicians and scientists meet in Sapporo for the AHCC Research Association symposium.
The supplement is Active Hexose Correlated Compound (AHCC). It is a medicinal mushroom extract originating in Japan, where it is used in more than 700 hospitals. Its introduction in the United States is more recent, dating back approximately 25 years. During this time, renowned universities across the country have subjected AHCC to a wide range of clinical studies, demonstrating time and again its effectiveness against cancer and other diseases. Technically, AHCC is what is called a "functional food," a dietary supplement with therapeutic properties.
Mushrooms and most mushroom-based supplements only provide the fruiting body of the fungus, which is its umbrella-shaped part.
AHCC, however, feeds on the fungal mycelium of medicinal mushrooms through a special cultivation process. The active ingredients are concentrated in the roots.
If the body is healthy, these cancer cells have no opportunity to act. Microscopic tumors develop, but immune cells "hunt them down" in a process of cellular immunity supported by immune cells such as natural killer cells, macrophages, and T cells, as well as by messengers—chemical substances that promote immunity—called cytokines.
AHCC boosts this cellular immunity. AHCC not only “stimulates” the immune system, but also modulates and directs it, making it smarter and more effective.
AHCC possesses a unique anticancer capacity: the activation of natural killer (NK) cells.
NK cells are activated and immediately spring into action through two pathways:
1) Releasing cytokines, which enhance the immune system's response.
2) Attacking tumor cells with substances that perforate their cell membrane (perforins) and enter them, inducing a kind of “self-destruction.”
AHCC has also demonstrated a significant effect on these tumor antigens. AHCC reduces tumor markers while increasing the strength of the immune system to help fight cancer.
The result is a decisive support against cancer, without the harmful side effects characteristic of modern cancer treatments such as chemotherapy and radiotherapy.
Larger Phase II studies (in this phase, safety and efficacy are examined) confirmed that AHCC can help prevent cancer in older adults by increasing key immune cytokines.
Studies also showed dramatic increases in survival rates for cancer patients, even those with late-stage or terminal diagnoses.
A large study with terminally ill patients with gastric, colon, liver, pancreatic, lung, breast, and ovarian cancers revealed a considerable increase in immune cell activity. While its properties against cancer and the effect of treatments are truly remarkable, the therapeutic indications for AHCC extend far beyond this.
There is ample scientific evidence demonstrating the efficacy of this compound against a wide range of conditions, including diabetes, chronic fatigue, oxidative stress, viral infections, and inflammation.
AHCC (Active Hexose Correlated Compound) is an extract obtained from the mycelium of the Lentinula edodes (Shiitake) mushroom that acts as a potent modulator of the immune system. Its relationship with NK cells (Natural Killer cells), fundamental in the defense against cancer and viruses, is notable for:
Increased activity: studies indicate that AHCC can increase NK cell activity by 200% to 300% in cancer patients.
Defense mechanism: NK cells detect and destroy abnormal or infected cells. AHCC enhances this ability to recognize and directly attack.
In general, studies on AHCC show that it is an immunomodulator: it can positively or negatively regulate immune activity depending on the context.
Innate immune system: it stimulates NK cells (natural killer cells), dendritic cells, and macrophages.
Adaptive immunity: it increases CD4+ and CD8+ T lymphocytes; It modulates the interferon pathways (IFN-β and IFN-γ).
Boosting the response of CD8+ T cells and NK cells helps the body fight cancer, especially in combination with chemotherapy and other cancer treatments. AHCC is being studied as an adjunct to chemotherapy, not as a standalone therapy.
In addition to its effect on T cells and NK cells, studies on colon cancer indicate that the glucans in AHCC also beneficially increase microbial diversity in the gut.
Japan's top oncologist, Professor Fukushima, condemns mRNA vaccines as "bad scientific practices"
"I am the most senior medical oncologist in Japan. I was the first to open an outpatient cancer clinic at Kyoto University, and before that, at Kyoto University, in 2020, I was head of a section at the Aichi Cancer Center; all positions were at the Aichi Cancer Center Hospital. I established the first pharmacoepidemiology course at Kyoto University in Japan. … There is talk of a type of cancer called 'turbo,' never seen by doctors before, characterized by an incredibly rapid rate of spread. When it is detected, it is already at stage four, advanced cancer, and these cases are starting to appear sporadically in consultations. That's why doctors started sharing information about these extraordinary cases, which are different from previous ones. So, gradually, this situation has been developing over the past year or the year before. In fact, doctors have been..." Sensing from the field that something unusual related to cancer might be happening. They were feeling it on the ground. …
Furthermore, the results of our analysis show, surprisingly, that some specific types of cancer, in relation to vaccination, appear to be experiencing excess mortality. First, cancers such as breast cancer, ovarian cancer, thyroid cancer, and, statistically, esophageal and lung cancer. These are, and another is prostate cancer in men. These cancers are specifically observing excess mortality. This phenomenon cannot be explained simply by disruptions such as the lack of availability of early testing due to the pandemic or the loss of treatment opportunities.
An ominous new peer-reviewed study has revealed that the United States suffered a staggering 1.5 million excess deaths among younger Americans who received Covid mRNA “vaccines” since the end of the pandemic.
The alarming findings show that excess mortality rates are soaring far higher among younger age groups in the United States when compared to other peer countries.
The researchers warn that the excess deaths among vaccinated Americans are twice as high as in 21 other wealthy countries, including Canada, the United Kingdom, Japan, France, and Australia.
The 1.5 million excess deaths were recorded among people under 65 across the United States during 2022 and 2023.
The study was led by Dr. Jacob Bor, associate professor of global health and epidemiology at the Boston University School of Public Health in Massachusetts.
Researchers from City University of New York, Cambridge Health Alliance, and Harvard Medical School collaborated for the study.
The results of the peer-reviewed study were published in the prestigious JAMA medical journal.
During the study, the researchers analyzed a whopping 107 million U.S. deaths from 1980 to 2023.
They also analyzed 230 million deaths from peer nations spanning the same period.
The data shows that excess deaths skyrocketed after Covid “vaccines” were rolled out for public use in early 2021.
The most dramatic spike came shortly after the vaccines emerged, with 1.1 million excess deaths recorded in 2021.
Excess deaths refer to the number of deaths during a specific time period that exceed what would be expected based on historical averages for the same period.
MyMountainResearch think tank is working on a Idea that all 'Diseases' are caused by a particular radio frequency.....
Now proven by N Tesla as to everything has a frequency that will cause that something to oscillate to the extent it will break down.. Example you can actually see is inside your microwave oven as water or the moisture in food make it get hot.....Microwave oven operate at 2.45 GHz.....4G&5G workers have been burned working on 4G&5G towers....proven by Professor J.C.Bose early 1900s and Tesla and dozens more...Light is also a proven Frequency 4-7 THz...but was changed it to Nm (maybe to confuse)
And there maybe be a much higher radiation that may be 'TIME' We think that 'Time 'is also a frequency..Russians may have stepped into that realm....as well a Tesla in the Philadelphia Experiment in 1930s....Kozyrev Mirrors >>>>
A Reader's Digest Version; More information, discussion revealing the bottom line, Our Bodies Want to be Healthy. Our Bodies Are Designed to be Healthy. Start from the beginning - Healthy clean foods to feed a Healthy Gut that in turn feeds a Healthy Foundational Mitochondrial Energy System while also Feeding an Immune System designed to not just keep us healthy, but allowing us to age more slowly - In other words a longer active life and abilities to engage in it with a healthy bodies, minds with healthy emotions. So much of this is denied us currently. Also as the article shares a massive Fortress of Status Quo has protected, fed itself on our Health. Change is not likely coming from the top down so the if Real Change is desired, Make It Local to Make it Real. And, be aware there are attempts and maneuvering to deny the individual States, local towns, city gov't's from blocking negative health offending projects - like 5G already already moving into 6G, or things as simple as Great Grandma's Old Victory Garden. Pick a project no matter how small you may think it is, even if it just window box gardens. Every drop in a bucket of positive projects coming from many sources will fill the bucket the Status Quo will be trying to punch as many holes in it as they can. While as individuals it is important for us to do as many positive things as we can, no one individual can do it all. We need each other, our differences, our different skills. Come Together Locally where we can see with our own eyes if it is actually real.
In 2000 I was diagnosed with terminal Perpherical T-Cell Lymphoma, 3 months! 4 chemos later, last one stopped because Oncologist said it was killing my red cells faster than I could make them, back to 3 months, go home and plan my funeral. This because at first oncologist ws giving me such vage answers. I kept bugging her, finally sent terse e-mail demanding a truthful answer. Her reply, she found most patients really do not want the hard truth! Then I said I would take her course on lymphoma. She said, have to take prequisites first. I said not if I audit! She sid I would still have to take the tests. She then brought me a textbook used in her class. I read it. asked questions, She answered, I took a test! Then another book! I now had a private tutor! Now we understood one another, she knew I was serious, welcomed the challenge! We were now both on apples, instead of apples and orsnges! Keep bugging doctors with questions!!! When chemos failed, I was visiting my chiropractor and she put me on Prayer, Organic, no sugar! Oncologist agreed to follow me on my experiment with labwork, X-Rays (0ver 20 rumors in each lung). At the end of 2001, I was in remission and then began follow ups to check if it came back. I have remained in remission now for 25 years! Because I now was on a healthy diet, I have not had to see a dentist since then, no cavities. Dibetes disgnosed same time as cancer, sugar was 585! They did not treat it as I was supposed to die in 3 months! I began taking Metformin and it with my new diet brought my sugar down, weight went from 295 to 137. BUT, I was unhappy with the side effects of Metformin, so when Gui suggested I use Berberine like he does, I switched to it. Now my sugar is controlled unless I have a poor me, pitty party and over indulge in ice cream, then I use insulin, usually 4 units.
Going organic, sugar free (if you have a aweet tooth, use Stevia, no side effects) has kept me healthy, living alone in the woods, 1 mile from humans, driving! Yes, chemo might help, but going organic should not be dismissed!
PERFECT, DORLIS YOU'VE CHOSEN THE RIGHT PATH.👍✌🏻❤️ I know someone with lymphoma whose bone marrow was destroyed by chemotherapy. Now they're undergoing stem cell treatment to regenerate it.
We have a pharmaceutical industry that prioritizes profits over people's health. Chemotherapy is very aggressive and weakens people's immune systems, jeopardizing their health. The truth is that when a person has cancer, they also develop cancer stem cells (CSCs) that are resistant to chemotherapy, although immunotherapy can, in some cases, help fight these stem cells by boosting each person's natural killer (NK) cells. However, it is prescribed less frequently due to its higher cost and side effects. NK cells, or Natural Killer cells, are immune cells with small particles containing enzymes capable of eliminating tumor cells or cells infected by a virus.
Recent studies lead us to believe that increasing the production of NK cells will enhance immune defense responses to eliminate cancerous or infected cells and improve overall health. For example, the use of probiotics has shown results of potentially increasing NK cell counts.
My doctoral thesis advisor had prostate cancer and, after six years, developed bone metastases. I know many other similar cases. A friend of my wife had stage 3 lung cancer and was treated with chemotherapy and immunotherapy. She then had a CT scan and appeared cured. However, she developed metastasis a few years later.
Other colleagues with advanced stomach and colon cancer also developed metastasis within a few years. I only know one friend with stage 2 colon cancer, without lymph node involvement, who did not undergo chemotherapy and is still alive after more than 5 years.
Many articles state that foods and supplements attack cancer stem cells.
The theory that cancer stem cells (CSCs) initiate and sustain various carcinogenic processes has been validated, and specific methods for identifying CSCs within the entire cancer cell population have also been shown to be effective. Studies provide an overview of recently acquired scientific knowledge regarding phytochemicals and herbal extracts, which have been shown to be capable of targeting and killing CSCs. Many genes and proteins that support the self-renewal capacity of CSCs and drug resistance have been described, and applications of phytochemicals capable of interfering with these signaling systems have been shown to be operationally efficient both in vitro and in vivo. The identification of specific surface antigens, mammosphere formation assays, serial colony-forming unit assays, xenograft transplantation, and tag retention assays, along with the evaluation of aldehyde dehydrogenase 1 (ALDH1) activity, are the most widely used techniques to measure phytochemical efficiency in CSC destruction.
Among chemopreventive dietary agents, the following are the most effective at reducing the proliferative activity of cancer cell lines: the polyphenol epigallocatechin-3-gallate (EGCG), curcumin, resveratrol, lycopene, pomegranate extracts, luteolin, genistein, piperine, β-carotene, and sulforaphane. These phytochemicals have been extensively studied for at least three decades. In fact, research on phytochemicals began even before the potential role of cancer cell lines (CSCs) in tumor development and spread was known. However, these studies provide a wealth of knowledge that can now be applied to the development of treatments against CSCs. Examples of these compounds are reported below.
EGCG, curcumin, piperine, sulforaphane, β-carotene, genistein, and whole extracts of some plants have been shown to be capable of killing CSCs. Most of these phytochemicals act by interfering with the canonical Wnt pathway (β-catenin/T-cell factor-lymphoid enhancer factor (TCF-LEF)) involved in the pathogenesis of several types of cancer. Therefore, the use of phytochemicals may be a true therapeutic strategy for eradicating cancer by eliminating cancer stem cells (CSCs).
EGCG is the most abundant polyphenol in green tea. It is capable of inducing caspase 8-dependent apoptosis in tumor cell cultures and animal models. Several clinical trials are underway involving EGCG alone or in combination with cisplatin and oxaliplatin due to EGCG's ability to synergistically increase the efficacy of these conventional drugs against prostate carcinoma and colorectal cancer.
Curcumin has been shown to disrupt the carcinogenic process by inhibiting the initiation step or suppressing the promotion and progression stages in animal models. Curcumin has also been reported to exhibit synergistic chemopreventive effects with other dietary polyphenols, such as genistein, EGCG, and embelin, and to enhance the efficacy of many cancer drugs, including 5-fluorouracil, vinca alkaloid, vinorelbine, cisplatin, and gemcitabine. It is important to highlight the significant role that various phytochemicals and bioactive compounds play in stimulating our immune system. Flavonoids are among the broad group of phenolic substances that possess antioxidant, anticancer, antimicrobial, cytotoxic, and antimutagenic properties. Consuming polyphenols (such as flavonoid-3-ols, procyanidins, catechins, flavones, resveratrol, anthocyanidins, and flavanones) can help maintain a healthy balance.
Fisetin, quercetin, apigenin, sulforaphane, and berberine are effective natural senolytics capable of activating autophagy (the mechanism for eliminating toxic elements stored in cells) and thus combating cancer. Everyday foods such as tea, onions, apples, and cucumbers contain fisetin, a flavonoid very similar to quercetin. According to experiments conducted by researchers at the American Scripps Research Institute, fisetin may prolong life. Apigenin is a compound found in vegetables and fruits that, according to a recently published laboratory study, weakens cancer cells, transforming them into normal, mortal cells. This compound is present in parsley, celery, and chamomile and weakens cancer cells. The links provide details of the phytochemicals present in food that attack cancer stem cells. Table 2 offers a brief summary of those capable of killing cancer stem cells, indicating the molecular mechanism involved in their action and the cellular marker. demonstrates its effect.
https://www.mdpi.com/1422-0067/16/7/15727/htm (2015).
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https://www.mdpi.com/1422-0067/23/24/16219 (2022).---
https://onlinelibrary.wiley.com/doi/full/10.1002/fft2.129 (2022).---
https://www.sciencedirect.com/science/article/abs/pii/S092422442200108X (2022).----
https://www.mdpi.com/2073-4409/12/6/915 (2023).---
https://www.sciencedirect.com/science/article/pii/S1568163723001022 (2023).----
https://www.apjtb.org/article.asp?issn=2221-1691;year=2021;volume=11;issue=1;spage=1;epage=9;aulast=Antika (2021)
https://onlinelibrary.wiley.com/doi/full/10.1002/fsn3.1872 (2021)
https://europepmc.org/article/ppr/ppr304849 (2021)
https://onlinelibrary.wiley.com/doi/full/10.1002/fft2.129 (2022).---
https://www.sciencedirect.com/science/article/abs/pii/S092422442200108X (2022).----
https://www.mdpi.com/2073-4409/12/6/915 (2023).---
https://www.cancer.gov/publications/dictionaries/cancer-terms/def/natural-killer-cell (2025).--
https://www.immunology.org/public-information/bitesized-immunology/cells/natural-killer-cells (2025).----
https://www.mdpi.com/2673-7523/5/2/27 (2025).---
https://pmc.ncbi.nlm.nih.gov/articles/PMC12838567/ (2026).—
https://www.mdpi.com/1422-0067/26/14/6894 (2026).-
https://pmc.ncbi.nlm.nih.gov/articles/PMC12655467/ (2026).--
Numerous studies have documented the antineoplastic properties of fungi, derived from two main sources: high-molecular-weight cell wall components (polysaccharides and proteoglycans) and low-molecular-weight secondary metabolites (terpenes, phenolic compounds, etc.). The primary anticancer mechanism is indirect and immunological, driven by polysaccharides and proteoglycans. These compounds act as immunomodulators, binding to pattern recognition receptors such as Dectin-1 and TLR2/4 on intestinal immune cells. This triggers a systemic cascade that enhances both innate and adaptive immunity. It promotes dendritic cell maturation, regulates the polarization of macrophages and helper T lymphocytes, increases natural killer (NK) cell populations, and elevates levels of key cytokines, such as IFN-γ, TNF-α, and IL-12. Although immune enhancement is well established, the potential involvement of complement receptor 3 (CR3) in fungal-mediated cytotoxicity, a critical pathway in therapy-induced cell death, remains an open and clinically significant question.
Unlike high-molecular-weight cell wall components, the direct anticancer activities of fungi are primarily due to a set of low-molecular-weight compounds (secondary metabolites). These compounds inhibit key signaling pathways and affect different characteristics of malignant cells. The potential synergy between high-molecular-weight cell wall components (polysaccharides and proteoglycans) and low-molecular-weight secondary metabolites, which combine immunomodulation with direct cytotoxicity, is a key area for preclinical research, particularly with "double" extracts that combine both. Furthermore, specific fungal immunomodulatory proteins (FIPs, such as LZ-8 and GMI) directly affect cancer cell signaling and represent promising adjuvants.
Some studies involve the regulation of pathway mechanisms, including the PI3K/AKT, EGFR/Raf, mTOR/AMPK, P53, Dectin-1/Syk/NF-κB, and TLR4/NF/κB signaling pathways. Furthermore, the mechanisms by which these compounds exert anticancer and immunomodulatory effects suggest that, in the future, these fungi, or their bioactive components, could be developed as drugs for targeted cancer therapies. Therefore, fungi present a valuable dual role as both food sources and potential therapeutic agents.
https://www.mdpi.com/2072-6643/17/11/1887 (2025).--
https://pmc.ncbi.nlm.nih.gov/articles/PMC12897983/ (2026).---
I can't add much more than what is alread
y said, just to say that treatments don't affect outcomes is because there no designed to affect outcomes. Infact they are designed to cement the evental return, and enhancing the profit to the treatment industry or healthcare establishment, however you prefer to call it/them.
Hi Merrill. WE NEED INTEGRATIVE MEDICINE OUTSIDE THE INTERESTS OF MULTINATIONAL PHARMACEUTICAL COMPANIES.
There is also an effective and scientifically supported anticancer supplement. Researchers at the Faculty of Pharmaceutical Sciences of the University of Tokyo developed Active Hexose Correlated Compound (AHCC) in 1987. Since then, AHCC has been the subject of more than 200 clinical studies, both in vitro and in vivo in humans and animals, primarily conducted in Japan.
Currently, more than 150 research projects are underway in laboratories and university hospitals in Japan and the United States, and each year more than 300 physicians and scientists meet in Sapporo for the AHCC Research Association symposium.
The supplement is Active Hexose Correlated Compound (AHCC). It is a medicinal mushroom extract originating in Japan, where it is used in more than 700 hospitals. Its introduction in the United States is more recent, dating back approximately 25 years. During this time, renowned universities across the country have subjected AHCC to a wide range of clinical studies, demonstrating time and again its effectiveness against cancer and other diseases. Technically, AHCC is what is called a "functional food," a dietary supplement with therapeutic properties.
Mushrooms and most mushroom-based supplements only provide the fruiting body of the fungus, which is its umbrella-shaped part.
AHCC, however, feeds on the fungal mycelium of medicinal mushrooms through a special cultivation process. The active ingredients are concentrated in the roots.
If the body is healthy, these cancer cells have no opportunity to act. Microscopic tumors develop, but immune cells "hunt them down" in a process of cellular immunity supported by immune cells such as natural killer cells, macrophages, and T cells, as well as by messengers—chemical substances that promote immunity—called cytokines.
AHCC boosts this cellular immunity. AHCC not only “stimulates” the immune system, but also modulates and directs it, making it smarter and more effective.
AHCC possesses a unique anticancer capacity: the activation of natural killer (NK) cells.
NK cells are activated and immediately spring into action through two pathways:
1) Releasing cytokines, which enhance the immune system's response.
2) Attacking tumor cells with substances that perforate their cell membrane (perforins) and enter them, inducing a kind of “self-destruction.”
AHCC has also demonstrated a significant effect on these tumor antigens. AHCC reduces tumor markers while increasing the strength of the immune system to help fight cancer.
The result is a decisive support against cancer, without the harmful side effects characteristic of modern cancer treatments such as chemotherapy and radiotherapy.
Larger Phase II studies (in this phase, safety and efficacy are examined) confirmed that AHCC can help prevent cancer in older adults by increasing key immune cytokines.
Studies also showed dramatic increases in survival rates for cancer patients, even those with late-stage or terminal diagnoses.
A large study with terminally ill patients with gastric, colon, liver, pancreatic, lung, breast, and ovarian cancers revealed a considerable increase in immune cell activity. While its properties against cancer and the effect of treatments are truly remarkable, the therapeutic indications for AHCC extend far beyond this.
There is ample scientific evidence demonstrating the efficacy of this compound against a wide range of conditions, including diabetes, chronic fatigue, oxidative stress, viral infections, and inflammation.
https://www.nutranews.org/recherche.pl?recherche=AHCC (2023).----
https://journals.lww.com/immunotherapy-journal/Citation/2006/11000/Prognostic_Improvement_of_Patients_With_Advanced.150.aspx (2006).----
http://ahccpublishedresearch.com/articles/wp-content/uploads/2016/07/I.J.-AHCC-2009-Kawaguchi-Human.pdf (2016).---
https://journals.sagepub.com/doi/pdf/10.1177/1534735417704948 (2017).---
https://www.tandfonline.com/doi/abs/10.1080/01635581.2018.1380203 (2018).---
https://etd.ohiolink.edu/apexprod/rws_olink/r/1501/10?clear=10&p10_accession_num=case161977862378657 (2021).---
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9066372/ (2022).---
https://www.hindawi.com/journals/ecam/2022/2923967/ (2022).---
https://trialsjournal.biomedcentral.com/articles/10.1186/s13063-021-05934-x (2022).---
https://ar.iiarjournals.org/content/43/3/1159.abstract (2023).---
AHCC (Active Hexose Correlated Compound) is an extract obtained from the mycelium of the Lentinula edodes (Shiitake) mushroom that acts as a potent modulator of the immune system. Its relationship with NK cells (Natural Killer cells), fundamental in the defense against cancer and viruses, is notable for:
Increased activity: studies indicate that AHCC can increase NK cell activity by 200% to 300% in cancer patients.
Defense mechanism: NK cells detect and destroy abnormal or infected cells. AHCC enhances this ability to recognize and directly attack.
In general, studies on AHCC show that it is an immunomodulator: it can positively or negatively regulate immune activity depending on the context.
Innate immune system: it stimulates NK cells (natural killer cells), dendritic cells, and macrophages.
Adaptive immunity: it increases CD4+ and CD8+ T lymphocytes; It modulates the interferon pathways (IFN-β and IFN-γ).
Boosting the response of CD8+ T cells and NK cells helps the body fight cancer, especially in combination with chemotherapy and other cancer treatments. AHCC is being studied as an adjunct to chemotherapy, not as a standalone therapy.
In addition to its effect on T cells and NK cells, studies on colon cancer indicate that the glucans in AHCC also beneficially increase microbial diversity in the gut.
A study of cancer stem cell lines demonstrated that AHCC alters microRNA expression. It increased the expression of miR-355, known for its tumor suppression benefits. [https://www.geneticlifehacks.com/ahcc-mushroom-compound-that-modulates-nk-and-t-cells/ (2026).--
Japan's top oncologist, Professor Fukushima, condemns mRNA vaccines as "bad scientific practices"
"I am the most senior medical oncologist in Japan. I was the first to open an outpatient cancer clinic at Kyoto University, and before that, at Kyoto University, in 2020, I was head of a section at the Aichi Cancer Center; all positions were at the Aichi Cancer Center Hospital. I established the first pharmacoepidemiology course at Kyoto University in Japan. … There is talk of a type of cancer called 'turbo,' never seen by doctors before, characterized by an incredibly rapid rate of spread. When it is detected, it is already at stage four, advanced cancer, and these cases are starting to appear sporadically in consultations. That's why doctors started sharing information about these extraordinary cases, which are different from previous ones. So, gradually, this situation has been developing over the past year or the year before. In fact, doctors have been..." Sensing from the field that something unusual related to cancer might be happening. They were feeling it on the ground. …
Furthermore, the results of our analysis show, surprisingly, that some specific types of cancer, in relation to vaccination, appear to be experiencing excess mortality. First, cancers such as breast cancer, ovarian cancer, thyroid cancer, and, statistically, esophageal and lung cancer. These are, and another is prostate cancer in men. These cancers are specifically observing excess mortality. This phenomenon cannot be explained simply by disruptions such as the lack of availability of early testing due to the pandemic or the loss of treatment opportunities.
https://www.globalresearch.ca/covid-19-vaccine-victims-families-speak-out/5861334?utm_campaign=magnet&utm_source=article_page&utm_medium=related_articles .---------------------------------------------------------
An ominous new peer-reviewed study has revealed that the United States suffered a staggering 1.5 million excess deaths among younger Americans who received Covid mRNA “vaccines” since the end of the pandemic.
The alarming findings show that excess mortality rates are soaring far higher among younger age groups in the United States when compared to other peer countries.
The researchers warn that the excess deaths among vaccinated Americans are twice as high as in 21 other wealthy countries, including Canada, the United Kingdom, Japan, France, and Australia.
The 1.5 million excess deaths were recorded among people under 65 across the United States during 2022 and 2023.
The study was led by Dr. Jacob Bor, associate professor of global health and epidemiology at the Boston University School of Public Health in Massachusetts.
Researchers from City University of New York, Cambridge Health Alliance, and Harvard Medical School collaborated for the study.
The results of the peer-reviewed study were published in the prestigious JAMA medical journal.
During the study, the researchers analyzed a whopping 107 million U.S. deaths from 1980 to 2023.
They also analyzed 230 million deaths from peer nations spanning the same period.
The data shows that excess deaths skyrocketed after Covid “vaccines” were rolled out for public use in early 2021.
The most dramatic spike came shortly after the vaccines emerged, with 1.1 million excess deaths recorded in 2021.
Excess deaths refer to the number of deaths during a specific time period that exceed what would be expected based on historical averages for the same period.
https://www.globalresearch.ca/excess-deaths-skyrocket-among-covid-vaxxed-young-americans/5897879?utm_campaign=magnet&utm_source=article_page&utm_medium=related_articles (2025)
Hi Gilliermou....How are you doing? long time -no see....so how is Spain? and yours?
All here in BC Canada is good......spring is soon coming...
Robb
Hi Robb
I'm fine, it's spring-like weather here in Spain too. There's been a lot of rain and damage to homes in the south of Spain. We live in the north.
MyMountainResearch think tank is working on a Idea that all 'Diseases' are caused by a particular radio frequency.....
Now proven by N Tesla as to everything has a frequency that will cause that something to oscillate to the extent it will break down.. Example you can actually see is inside your microwave oven as water or the moisture in food make it get hot.....Microwave oven operate at 2.45 GHz.....4G&5G workers have been burned working on 4G&5G towers....proven by Professor J.C.Bose early 1900s and Tesla and dozens more...Light is also a proven Frequency 4-7 THz...but was changed it to Nm (maybe to confuse)
..>> https://www.unitconverters.net/frequency-wavelength/terahertz-to-wavelength-in-nanometres.htm <<< light is also an Ionizing Radiation,,,it makes its own power...that why light i warm and can easily burn a human as a sunburn is a 'Radiation Burn'...X-rays and burn as can any radiation can do...non-ionizing and ionizing radiation .
And there maybe be a much higher radiation that may be 'TIME' We think that 'Time 'is also a frequency..Russians may have stepped into that realm....as well a Tesla in the Philadelphia Experiment in 1930s....Kozyrev Mirrors >>>>
https://pikabu.ru/story/zerkala_kozyireva_4167940
A Reader's Digest Version; More information, discussion revealing the bottom line, Our Bodies Want to be Healthy. Our Bodies Are Designed to be Healthy. Start from the beginning - Healthy clean foods to feed a Healthy Gut that in turn feeds a Healthy Foundational Mitochondrial Energy System while also Feeding an Immune System designed to not just keep us healthy, but allowing us to age more slowly - In other words a longer active life and abilities to engage in it with a healthy bodies, minds with healthy emotions. So much of this is denied us currently. Also as the article shares a massive Fortress of Status Quo has protected, fed itself on our Health. Change is not likely coming from the top down so the if Real Change is desired, Make It Local to Make it Real. And, be aware there are attempts and maneuvering to deny the individual States, local towns, city gov't's from blocking negative health offending projects - like 5G already already moving into 6G, or things as simple as Great Grandma's Old Victory Garden. Pick a project no matter how small you may think it is, even if it just window box gardens. Every drop in a bucket of positive projects coming from many sources will fill the bucket the Status Quo will be trying to punch as many holes in it as they can. While as individuals it is important for us to do as many positive things as we can, no one individual can do it all. We need each other, our differences, our different skills. Come Together Locally where we can see with our own eyes if it is actually real.
In 2000 I was diagnosed with terminal Perpherical T-Cell Lymphoma, 3 months! 4 chemos later, last one stopped because Oncologist said it was killing my red cells faster than I could make them, back to 3 months, go home and plan my funeral. This because at first oncologist ws giving me such vage answers. I kept bugging her, finally sent terse e-mail demanding a truthful answer. Her reply, she found most patients really do not want the hard truth! Then I said I would take her course on lymphoma. She said, have to take prequisites first. I said not if I audit! She sid I would still have to take the tests. She then brought me a textbook used in her class. I read it. asked questions, She answered, I took a test! Then another book! I now had a private tutor! Now we understood one another, she knew I was serious, welcomed the challenge! We were now both on apples, instead of apples and orsnges! Keep bugging doctors with questions!!! When chemos failed, I was visiting my chiropractor and she put me on Prayer, Organic, no sugar! Oncologist agreed to follow me on my experiment with labwork, X-Rays (0ver 20 rumors in each lung). At the end of 2001, I was in remission and then began follow ups to check if it came back. I have remained in remission now for 25 years! Because I now was on a healthy diet, I have not had to see a dentist since then, no cavities. Dibetes disgnosed same time as cancer, sugar was 585! They did not treat it as I was supposed to die in 3 months! I began taking Metformin and it with my new diet brought my sugar down, weight went from 295 to 137. BUT, I was unhappy with the side effects of Metformin, so when Gui suggested I use Berberine like he does, I switched to it. Now my sugar is controlled unless I have a poor me, pitty party and over indulge in ice cream, then I use insulin, usually 4 units.
Going organic, sugar free (if you have a aweet tooth, use Stevia, no side effects) has kept me healthy, living alone in the woods, 1 mile from humans, driving! Yes, chemo might help, but going organic should not be dismissed!
PERFECT, DORLIS YOU'VE CHOSEN THE RIGHT PATH.👍✌🏻❤️ I know someone with lymphoma whose bone marrow was destroyed by chemotherapy. Now they're undergoing stem cell treatment to regenerate it.