Dr. Mercola's Censored Library (Private Membership)

Dr. Mercola's Censored Library (Private Membership)

Discussion about this post

User's avatar
Just steve's avatar
Just steve
19h

Back in the day, 60s, 70's, in this rural area especially the farmers at or above retirement age many were so active, high functioning they would shock, stun people today what they would, could do. The big concern was heart attacks. If the first one didn't kill you, the second one soon after would. Most likely the affects of seed oil use becoming common a few decades earlier. Cancers as a health concern fear took over in later years. They may not have been doing things perfect but better than the toxic, sterilizing, lobotomizing sea we swim in assaulting us today.

Sturdy farm stock engaged with Creation, exposed to wide ranges of microbes, fresh grown and picked foods with all of it engaged with constant physical movement of some kind. Taking it easy, the good life, the Life of Riley was observed as the road to ill health, decline.

An expression often heard was, no time to be sitting here doing nothing, there must be something needing to be done. They looked for reasons to be up and moving., keep going. So many didn't begin to slow down until their late 80s' or into their 90s'. Even then still strong compared to the townies, the farmer usually called the bankers.

Reply
Share
Guillermou's avatar
Guillermou
1d

My fasting insulin is excellent at 2.1 and my glucose is 75-80; these are two important indicators of mitochondrial health. Mitochondrial dysfunction is linked to the origin of many chronic and degenerative diseases, and its treatment is fundamental to preventing insulin resistance. In addition to energy production, mitochondria perform multiple essential functions that influence gene expression within the cell nucleus and physiological regulation throughout the body. In particular, mitochondria are the main producers of reactive oxygen species (ROS) within the cell, which play a role in signaling and other life-sustaining functions at low levels, but can cause oxidative stress when they overwhelm antioxidant defense mechanisms. They also play a key role in neurodegenerative processes and the pathophysiology of stress and aging, specifically in cellular metabolic activity, DNA damage, telomere length, cellular senescence, and inflammatory response patterns.

A decrease in systemic levels of NAD+ is a crucial factor in the deterioration of the organism during aging. This is further supported by the overall therapeutic effect of NAD+ boosters in several animal models of common age-related conditions, ranging from diabetes and obesity, non-alcoholic fatty liver disease, kidney injury, renal failure, muscle function and sarcopenia, glaucoma, ischemia-reperfusion injury, vascular dysfunction, and cognitive decline.

https://www.annualreviews.org/doi/abs/10.1146/annurev-publhealth-040119-094239 (2020)

https://www.scie.ncedirect.com/science/article/pii/S1568163721002543 (2022)

https://karger.com/dne/article/44/6/438/835327 (2022).--

https://www.sciencedirect.com/science/article/pii/S0889159122001477 (2022)

https://www.nature.com/articles/s43587-022-00191-2 (2022).---

https://www.sciencedirect.com/science/article/pii/S0959438822001696 (2023)

Mitochondrial dysfunction is caused by poor nutrition, highly processed and pesticide-contaminated food, high sugar and additive loads, vaccines, fluoridated and contaminated water, stress, etc. Linoic acid is a major contributor to mitochondrial dysfunction.

Mitochondria are especially abundant in the organs and tissues of the body with the highest energy requirements. Supplements and lifestyle changes can improve mitochondrial health by increasing the availability of proteins necessary for ATP production (activation of AMPK, PCG-1a, NAD+, and SIRT1). They also act as antioxidants, helping mitochondria reduce oxidative stress and perform other important functions, including signaling, differentiation, programmed cell death, and cell growth control.

Additional support for mitochondrial function includes acetyl-L-carnitine, nicotinamide, CoQ10, pyrroloquinoline quinone, vitamin C, choline, NADH, alpha-lipoic acid, alpha-ketoglutaric acid, resveratrol, N-acetylcysteine, magnesium, and a quality multivitamin and mineral complex. For more information, see the following link:

33 NATURAL WAYS TO IMPROVE MITOCHONDRIAL FUNCTION

https://selfhacked.com/blog/natural-ways-to-improve-mitochondrial-function/ (2022). .---

http://onlinelibrary.wiley.com/doi/10.1111/cns.12655/full (2017).---

https://www.annualreviews.org/doi/abs/10.1146/annurev-pharmtox-010716-104908 (2018).--

https://link.springer.com/book/10.1007%2F978-3-319-73344-9#page=493 (2018).--- A large group of plant-produced compounds called phytochemicals, which possess high antioxidant properties, have been shown to be useful in combating numerous diseases. This review covered the antioxidant potential of some plants with these properties. Medicinal plants. A total of 250 plants from the following families; these plants exhibit important biological properties, such as anti-inflammatory, antioxidant, immunomodulatory, anticancer, and antimicrobial properties, among others.

https://www.tandfonline.com/doi/full/10.1080/10942912.2022.2157425 (2022)

La evidencia esta demostrando que la obesidad, diabetes. alzheimer (diabetes tipo 3) y enfermedsdes crónicas y degenerativas, incluido el cancer estan relacionadas de la resistencia a la insulina al predecir una variedad de enfermedades metabólicas y relacionadas tambien con la edad..La resistencia a la insulina define un deterioro en la respuesta biológica a la estimulación de la insulina de los tejidos diana, principalmente el hígado, los músculos, el tejido adiposo y el cerebro. La incapacidad para llevar a cabo la eliminación de glucosa da como resultado un aumento en la producción de insulina de las células β e hiperinsulinemia. La RI afecta la fisiología de muchas maneras, causando hiperglucemia, hipertensión, dislipidemia, adiposidad visceral, hiperuricemia, marcadores inflamatorios elevados y disfunción endotelial. Si persiste en el tiempo, puede conducir al desarrollo de síndrome metabólico, NAFLD, enfermedades cardiovasculares (ECV), enfermedad de Alzheimer (EA) y, más comúnmente, cuando las células β no pueden mantener el ritmo y la producción de insulina disminuye gradualmente hasta detenerse. diabetes mellitus tipo 2 . La resistencia a la insulina precede y causa inflamación en el tejido adiposo .

Nutrientes como el resveratrol, los extractos de antocianinas de plantas moradas, la curcumina o los flavonoides tienen un papel relevante en la mejora de la resistencia a la insulina a niveles moleculares. La restricción calórica es una intervención no farmacológica que se sabe que mejora los defectos metabólicos asociados con el envejecimiento, incluida la resistencia a la insulina. Los niveles de expresión de miARN pueden representar una herramienta predictiva de alteraciones relacionadas con el envejecimiento

https://www.mdpi.com/2218-273X/12/2/208 (2022).---

https://www.sciencedirect.com/science/article/abs/pii/S1471489221001752 (2022).---

https://www.mdpi.com/2077-0383/11/15/4358 (2022).---

https://www.mdpi.com/2218-273X/13/5/779 (2023).---

https://onlinelibrary.wiley.com/doi/full/10.1111/acel.13919 (2023).---

Reply
Share

No posts

Ready for more?

© 2026 Dr. Joseph Mercola · Privacy ∙ Terms ∙ Collection notice
Start your SubstackGet the app
Substack is the home for great culture