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Guillermou's avatar

This review and other studies report that GABA is a major inhibitory neurotransmitter in the central nervous system, modulating synaptic transmission, promoting neuronal development and relaxation, and preventing insomnia and depression. GABA has antihypertensive, antidiabetic, anticancer, antioxidant, anti-inflammatory, antimicrobial, antiallergic, hepatoprotective, and intestinal protective properties. GABA may suppress neurodegeneration and improve memory and cognitive function, as well as brain function, neurodegenerative and cerebrovascular diseases, neuroinfections, and insomnia. Fatigue, or extreme tiredness, is a common symptom of diabetes. GABA and GABA-enriched natural products have been shown to be effective agents in lowering blood glucose, attenuating insulin resistance, stimulating insulin release, and preventing pancreatic damage. Germinated rice and fermented foods contain significant amounts of GABA and have potential antidiabetic activity. They increase superoxide dismutase and glutathione peroxidase activity in the cerebral cortex.

Altered gut microbiota, mucosal barrier dysfunction, and aberrant intestinal immunity contribute to the pathogenesis of chronic fatigue.

GABA combats intestinal inflammation and improves the intestinal epithelial barrier. GABA tea extract exhibited inhibitory activity.

GABA has an effect on growth performance, intestinal immunity, and the intestinal microflora of weaned piglets. GABA improved growth performance, inhibited pro-inflammatory cytokine expression, promoted anti-inflammatory cytokine expression, and increased dominant microbial populations, community richness, and ileal microbiota diversity.

https://www.mdpi.com/1420-3049/24/15/2678/htm (2019).---

https://www.thesciencebrigade.com/jst/article/view/164 (2024).---

https://pubs.acs.org/doi/abs/10.1021/acs.jafc.3c07260 (2024).---

Just steve's avatar

So what causes peoples Depression, as well as Mental Illness, and violence? More important, what prevents all these? One factor? Being Civilized to Death drowning in a sea of toxins before the Head Med's even enter the scene. So much shared the last few days to renew, regenerate Health in all levels of life along with our own. Yesterdays article on agriculture describing Whole Systems! Same, similar for Health. The Reductionist Model is just fine for discovery of narrow, focused study of different processes, but this fails because selfish interests do not extend what are the Risk vs. The Rewards far enough. Much to do is made this solves this one narrow subject but totally ignore how or what the effects are when viewed with a vision including Whole Systems, Processes. To some it may be in their opinion a great Ca$h Cow business model, but if the future follows what has been imposed on us, what will they do when "we Cows" are all dead?

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