Aloe vera has revealed its potential in managing various health conditions including skin problems, digestive problems, diabetes, immune system support and even cancer-related.
Irritable bowel syndrome (IBS) is a common gastrointestinal disorder that is diagnosed based on symptoms such as changes in bowel habits and abdominal discomfort without any organic cause. Multiple factors including altered brain-gut interactions, visceral hypersensitivity, intestinal dysbiosis, increased intestinal permeability and psychosocial factors contribute to the pathogenesis of IBS. Aloe vera (AV) is an herbal medicine used as a remedy for various diseases in traditional medicine. It has been shown to have hepatoprotective, anti-inflammatory and antiulcer benefits.
The polysaccharides present in the Aloe vera pulp, N-acetylglucosamine and N-acetylcysteine possess anti-inflammatory action. It is advisable that when consuming Aloe vera pulp extracts, they are free of aloin, as this compound has a mild laxative effect.
The larger polysaccharides of Aloe vera and arabinogalactans (larch polysaccharides) are capable of strengthening the immune system . The latter have been shown to increase the production of short-chain fatty acids, mainly butyrate and propionate, energy sources of the epithelial cells of the colon . Evidence also indicates that human consumption of larch arabinogalactans has a significant effect on improving the beneficial intestinal microbiota, specifically increasing bifidobacteria and lactobacillus .
Aloe vera has revealed its potential in managing various health conditions including skin problems, digestive problems, diabetes, immune system support and even cancer-related.
Irritable bowel syndrome (IBS) is a common gastrointestinal disorder that is diagnosed based on symptoms such as changes in bowel habits and abdominal discomfort without any organic cause. Multiple factors including altered brain-gut interactions, visceral hypersensitivity, intestinal dysbiosis, increased intestinal permeability and psychosocial factors contribute to the pathogenesis of IBS. Aloe vera (AV) is an herbal medicine used as a remedy for various diseases in traditional medicine. It has been shown to have hepatoprotective, anti-inflammatory and antiulcer benefits.
The polysaccharides present in the Aloe vera pulp, N-acetylglucosamine and N-acetylcysteine possess anti-inflammatory action. It is advisable that when consuming Aloe vera pulp extracts, they are free of aloin, as this compound has a mild laxative effect.
The larger polysaccharides of Aloe vera and arabinogalactans (larch polysaccharides) are capable of strengthening the immune system . The latter have been shown to increase the production of short-chain fatty acids, mainly butyrate and propionate, energy sources of the epithelial cells of the colon . Evidence also indicates that human consumption of larch arabinogalactans has a significant effect on improving the beneficial intestinal microbiota, specifically increasing bifidobacteria and lactobacillus .
In these reviews and meta-analyses, AV showed an improvement in symptom scores in patients with diarrhea-predominant or mixed-type IBS, especially in terms of the subscores of pain and satisfaction with bowel habits. Recently, probiotics originating from AV leaves, such as Lactobacillus brevis strains, selectively inhibited the growth of harmful enteropathogens in the intestine. In a placebo-controlled trial, L. brevis KB290 significantly reduced the frequency of watery stools and abdominal pain in patients with IBS. These findings suggest that the efficacy of AVs in diarrhea-predominant or mixed-type IBS may be explained by the probiotic effects of AVs. https://www.researchgate.net/profile/Hussein-Elaibi/publication/373216937_A_comprehensive_review_of_Aloe_vera_Multifaceted_health_benefits_and_anti-diabetic_properties/links/64e0a52fcaf5ff5cd0c75ec9/A-comprehensive-review-of-Aloe-vera-Multifaceted-health-benefits-and-anti-diabetic-properties.pdf (2023).---
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175553/ (2018) healthy.-----