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Aloe vera has revealed its potential in managing various health conditions including skin problems, digestive problems, diabetes, immune system support and even related to cancer.

Irritable bowel syndrome (IBS) is a common gastrointestinal disorder that is diagnosed based on symptoms such as changes in bowel habits and abdominal discomfort without any organic cause. Multiple factors, including altered brain-gut interactions, visceral hypersensitivity, intestinal dysbiosis, increased intestinal permeability, and psychosocial factors contribute to the pathogenesis of IBS. Aloe vera (AV) is a herbal medicine used as a remedy for various diseases in traditional medicine. It has been shown to have hepatoprotective, anti-inflammatory and anti-ulcer benefits.

The polysaccharides present in the pulp of Aloe vera, N-acetylglucosamine and N-acetylcysteine, have an anti-inflammatory action. It is advisable that when consuming Aloe vera pulp extracts, they are free of aloin, since this compound has a slight laxative effect.

The larger polysaccharides of Aloe vera and arabinogalactans (polysaccharides of larch) are capable of strengthening the immune system. The latter have been shown to increase the production of short-chain fatty acids, mainly butyrate and propionate, energy sources for colon epithelial cells. Evidence also indicates that human consumption of arabinogalactans from larch has a significant effect on improving beneficial gut microbiota, specifically increasing bifidobacteria and lactobacillus.

In these reviews and meta-analyses, AV showed an improvement in symptom scores in patients with diarrhea-predominant or mixed-type IBS, especially in terms of pain subscores and satisfaction with bowel habits. Recently, probiotics originated from AV leaves, such as Lactobacillus brevis strains, selectively inhibited the growth of harmful enteropathogens in the intestine. In a placebo-controlled trial, L. brevis KB290 significantly reduced the frequency of watery stools and abdominal pain in patients with IBS. These findings suggest that the efficacy of AVs in diarrhea-predominant or mixed-type IBS may be explained by the probiotic effects of AVs.

https://www.researchgate.net/profile/hussein-elaibi/publication/373216937_a_comprehensive_review. C75ec9/A-Comprehensive-Review-Off-Aloe-Vere-Multifaceted-Health-Benefits-And-Diabetic- Diabetic- properties.pdf (2023).---

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175553/ (2018).---

https://www.taylorfrancis.com/chapters/edit/10.1201/9781003189749-14/role-aloe-vera-irritable-bowel-disease-dilipkumar-pal-souvik-mukherjee (2022).--

https://www.cienporciennatural.com/biblioteca/como-mantener-un-sistema-gastrointestinal-sano .-----

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