The International Agency for Research on Cancer has now classified this artificial sweetener as a possible carcinogen, affirming my campaign against it.
As always, the evidence shows how the WHO and other institutions have supported the agri-food industry by proposing food pyramids that promote the disease. Autoimmune diseases have grown rapidly in recent years, with more than 50 million Americans affected. When the intestine is damaged, undigested food proteins and bacterial endotoxins pass through the lining of the intestine and cause an autoimmune reaction throughout the body. Wheat, stress, artificial sweeteners, sugar, toxins from processed foods, environmental pollution, genetics, etc. are triggers.
Stress along with artificial sweeteners can enhance changes in the microbiota and lining of the intestine, in addition to further increasing intestinal inflammation. Maternal serum aspartame levels were positively associated with insulin resistance, and LDL cholesterol during pregnancy caused by energy imbalance, alteration of intestinal microbiota, alteration of neuroendocrine balance and oxidant/antioxidant activities.
As aspartame is a chemical stressor of brain HPA, aspartame supplementation can elevate corticosterone levels, increase muscarinic receptor density, and inhibit serotonin, norepinephrine, and dopamine in the brain, consequently resulting in a abnormal glucose metabolism.
Furthermore, ingestion of aspartame in rodents caused liver damage through antioxidant status. It has been reported that aspartame consumption could cause neurological and behavioral disorders. Ingestion of aspartame results in a craving for carbohydrates, which will eventually result in weight gain, especially since formaldehyde is stored in fat cells and causes problems in diabetes control.
This systematic review sheds light on how excessive consumption of artificially sweetened beverages can affect multiple organ systems, and associations have been made with mental health burden, delays in childhood neurodevelopment, cardiac remodeling, worsening of retinopathy in diabetics, incidental end-stage renal disease, non-Hodgkin lymphoma and multiple myeloma in men, rheumatoid arthritis in women, hip fractures, dental erosion, increases in breath alcohol concentration when used in alcoholic beverages, and cellular aging accelerated.
As always, the evidence shows how the WHO and other institutions have supported the agri-food industry by proposing food pyramids that promote the disease. Autoimmune diseases have grown rapidly in recent years, with more than 50 million Americans affected. When the intestine is damaged, undigested food proteins and bacterial endotoxins pass through the lining of the intestine and cause an autoimmune reaction throughout the body. Wheat, stress, artificial sweeteners, sugar, toxins from processed foods, environmental pollution, genetics, etc. are triggers.
https://www.sciencedirect.com/science/article/pii/S1568997215000245 (2015).----
https://hero.epa.gov/hero/index.cfm/reference/details/reference_id/6268261 (2018).----
https://www.researchgate.net/profile/Adekunle-Sanyaolu/publication/354820981_Effect_of_Artificial_Sweeteners_on_the_Gut_Microbiome/links/614e2787f8c9c51a8aeedb48/Effect-of-Artificial-Sweeteners-on-the-Gut-Microbiome.pdf (20 19).-----
https://www.mdpi.com/2072-6643/12/6/1862 (2020).---
https://www.frontiersin.org/articles/10.3389/fnut.2022.848392/full (2022).---
https://www.proquest.com/openview/80b95b24dbab5893c1a3f69f04fa3cfa/1?pq-origsite=gscholar&cbl=2045583 (2023).---
Stress along with artificial sweeteners can enhance changes in the microbiota and lining of the intestine, in addition to further increasing intestinal inflammation. Maternal serum aspartame levels were positively associated with insulin resistance, and LDL cholesterol during pregnancy caused by energy imbalance, alteration of intestinal microbiota, alteration of neuroendocrine balance and oxidant/antioxidant activities.
As aspartame is a chemical stressor of brain HPA, aspartame supplementation can elevate corticosterone levels, increase muscarinic receptor density, and inhibit serotonin, norepinephrine, and dopamine in the brain, consequently resulting in a abnormal glucose metabolism.
Furthermore, ingestion of aspartame in rodents caused liver damage through antioxidant status. It has been reported that aspartame consumption could cause neurological and behavioral disorders. Ingestion of aspartame results in a craving for carbohydrates, which will eventually result in weight gain, especially since formaldehyde is stored in fat cells and causes problems in diabetes control.
https://www.scirp.org/html/13-8204292_84959.htm?pagespeed=noscript&ref=ourbrew.ph (2018)
https://www.mdpi.com/2072-6643/14/23/5001 (2022)
This systematic review sheds light on how excessive consumption of artificially sweetened beverages can affect multiple organ systems, and associations have been made with mental health burden, delays in childhood neurodevelopment, cardiac remodeling, worsening of retinopathy in diabetics, incidental end-stage renal disease, non-Hodgkin lymphoma and multiple myeloma in men, rheumatoid arthritis in women, hip fractures, dental erosion, increases in breath alcohol concentration when used in alcoholic beverages, and cellular aging accelerated.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9891650/ (2023)