Many critics claim that one of the places where there is the most varied and complete gastronomy in the world is in the Basque Country. Innovation and excellence in the Basque Country also extends to haute cuisine, where there is the highest concentration of Michelin stars per capita in the world.
Bone broth from the famous chef Arguiñano is also a perfect option. With its intense flavor and full of nutrients, this broth is ideal for fighting the cold and taking care of your health. Discover how renowned chef Karlos Arguiñano has created a unique recipe full of flavors that will make you want to repeat again and again. Get ready to enjoy a traditional dish with a modern touch that will leave you completely satisfied. Don't miss this opportunity to taste Arguiñano's incredible bone broth!
Osteoarthritis (OA) is becoming one of the most common joint conditions due to the increase in life expectancy, representing today an important socioeconomic and public health problem. OA is characterized by the progressive inflammation and destruction of articular cartilage, affecting any joint, although it is more common in the knee, hip, spine and interphalangeal joints, causing pain, functional limitations and reduced quality of life.
Gelatin is probably the most common form on the market, but no biological function for joint health has been described. However, it has excellent physical and mechanical properties such as low solubility and proper handling, mainly because it is composed of a mixture of peptides with different molecular weights. Therefore, gelatin is widely used in the manufacturing of different food systems, such as capsules and films.
Hydrolyzed collagens are composed of amino acids and peptides of variable length (including dipeptides and tripeptides) that resist the intracellular hydrolysis process, preventing their degradation by peptidases and systemic hydrolytic enzymes. Thus, hydrolyzed collagen peptides have a high bioavailability that allows them to reach the bloodstream, accumulating in the cartilage tissue and inducing the synthesis of cartilage ECM, stimulating chondrocytes.
The differences in the mechanisms of action described for native and hydrolyzed collagens could even theoretically justify a possible combination of both types of collagens to explore complementary effects.
Type II collagen (the major protein in articular cartilage) has been shown to be a potential source of autoantigens in OA. Consequently, oral tolerance to type II collagen could theoretically have a positive impact on the control of inflammation in OA. Indeed, the efficacy of oral administration of low doses of native collagen type II has been demonstrated in animal models of OA, such as the rat model of monoiodoactetate (MIA)-induced OA. In this model, oral administration of native chicken type II collagen (1 to 10 mg/kg) reduced joint pain, decreased plasma concentration of inflammatory cytokines (TNFa, IL-1b), and reduced cartilage degradation, as demonstrates a reduction in the plasma concentration of inflammatory cytokines (TNFa, IL-1b). C2C levels.
Hydrolyzed collagen has been shown to contain biologically active peptides that can reach joint tissues and exert chondroprotective effects. There are preclinical and clinical studies that demonstrate the safety and effectiveness of ingredients containing native type II collagen or hydrolyzed collagen. However, available research suggests a clear link between the chemical composition/structure of collagen ingredients and the mechanism of action/efficacy.
Collagen promotes heart health by providing structure to arteries, the vessels that carry blood from the heart throughout the body. Without adequate structural support, arteries become weak, stiff, and inflexible, which is linked to an increased risk of cardiovascular disease, heart attacks, and strokes.
Some research suggests that collagen may keep arteries healthy and strong. In a small study, people who took a collagen supplement with breakfast and dinner (for a total of 16 grams per day) showed a significant reduction in arterial stiffness. Another study found that 2.5 grams of collagen per day had similar effects in reducing arterial stiffness.
Several indicators of premature atherosclerosis have been described. The ratio between low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (HDL-C) (LDL-C/HDL-C ratio) indicates the balance between the two types of cholesterol associated with events. cardiovascular. The LDL-C/HDL-C ratio is reported to have utility as a predictor of carotid intima-media thickness (IMT). Furthermore, plaque area increases rapidly when the LDL-C/HDL-C ratio becomes >2.5. In healthy people, correlations have been observed between the LDL-C/HDL-C ratio and risk factors for atherosclerosis.
Collagen provides structure to arteries, which keeps blood flowing to and from the heart. Studies have shown that taking collagen supplements can reduce the stiffness of the arteries and increase levels of "good" HDL cholesterol in the body. This means it can help reduce the risk of developing heart disease. The results of the present study indicate that the collagen tripeptide CTP contributes to the prevention and treatment of atherosclerosis in healthy humans.
Many critics claim that one of the places where there is the most varied and complete gastronomy in the world is in the Basque Country. Innovation and excellence in the Basque Country also extends to haute cuisine, where there is the highest concentration of Michelin stars per capita in the world.
Bone broth from the famous chef Arguiñano is also a perfect option. With its intense flavor and full of nutrients, this broth is ideal for fighting the cold and taking care of your health. Discover how renowned chef Karlos Arguiñano has created a unique recipe full of flavors that will make you want to repeat again and again. Get ready to enjoy a traditional dish with a modern touch that will leave you completely satisfied. Don't miss this opportunity to taste Arguiñano's incredible bone broth!
Ingredients for Arguiñano Bone Broth:
-----2 kg of beef bones
-----1 large onion
-----2 carrots
-----2 leeks
-----2 sticks of celery
-----1 tomato
-----4 cloves of garlic
-----1 bay leaf
-----Salt to taste
---- Black pepper to taste
-----Water
https://productosluque.es/caldo-de-huesos-arguinano/?expand_article=1
FAMOUS RECIPES OF SPANISH CUISINE
https://www.larecettedujour.org/tag/spanish
Osteoarthritis (OA) is becoming one of the most common joint conditions due to the increase in life expectancy, representing today an important socioeconomic and public health problem. OA is characterized by the progressive inflammation and destruction of articular cartilage, affecting any joint, although it is more common in the knee, hip, spine and interphalangeal joints, causing pain, functional limitations and reduced quality of life.
Gelatin is probably the most common form on the market, but no biological function for joint health has been described. However, it has excellent physical and mechanical properties such as low solubility and proper handling, mainly because it is composed of a mixture of peptides with different molecular weights. Therefore, gelatin is widely used in the manufacturing of different food systems, such as capsules and films.
Hydrolyzed collagens are composed of amino acids and peptides of variable length (including dipeptides and tripeptides) that resist the intracellular hydrolysis process, preventing their degradation by peptidases and systemic hydrolytic enzymes. Thus, hydrolyzed collagen peptides have a high bioavailability that allows them to reach the bloodstream, accumulating in the cartilage tissue and inducing the synthesis of cartilage ECM, stimulating chondrocytes.
The differences in the mechanisms of action described for native and hydrolyzed collagens could even theoretically justify a possible combination of both types of collagens to explore complementary effects.
Type II collagen (the major protein in articular cartilage) has been shown to be a potential source of autoantigens in OA. Consequently, oral tolerance to type II collagen could theoretically have a positive impact on the control of inflammation in OA. Indeed, the efficacy of oral administration of low doses of native collagen type II has been demonstrated in animal models of OA, such as the rat model of monoiodoactetate (MIA)-induced OA. In this model, oral administration of native chicken type II collagen (1 to 10 mg/kg) reduced joint pain, decreased plasma concentration of inflammatory cytokines (TNFa, IL-1b), and reduced cartilage degradation, as demonstrates a reduction in the plasma concentration of inflammatory cytokines (TNFa, IL-1b). C2C levels.
Hydrolyzed collagen has been shown to contain biologically active peptides that can reach joint tissues and exert chondroprotective effects. There are preclinical and clinical studies that demonstrate the safety and effectiveness of ingredients containing native type II collagen or hydrolyzed collagen. However, available research suggests a clear link between the chemical composition/structure of collagen ingredients and the mechanism of action/efficacy.
https://www.mdpi.com/2072-6643/15/6/1332 (2023).--
Collagen promotes heart health by providing structure to arteries, the vessels that carry blood from the heart throughout the body. Without adequate structural support, arteries become weak, stiff, and inflexible, which is linked to an increased risk of cardiovascular disease, heart attacks, and strokes.
Some research suggests that collagen may keep arteries healthy and strong. In a small study, people who took a collagen supplement with breakfast and dinner (for a total of 16 grams per day) showed a significant reduction in arterial stiffness. Another study found that 2.5 grams of collagen per day had similar effects in reducing arterial stiffness.
Several indicators of premature atherosclerosis have been described. The ratio between low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (HDL-C) (LDL-C/HDL-C ratio) indicates the balance between the two types of cholesterol associated with events. cardiovascular. The LDL-C/HDL-C ratio is reported to have utility as a predictor of carotid intima-media thickness (IMT). Furthermore, plaque area increases rapidly when the LDL-C/HDL-C ratio becomes >2.5. In healthy people, correlations have been observed between the LDL-C/HDL-C ratio and risk factors for atherosclerosis.
Collagen provides structure to arteries, which keeps blood flowing to and from the heart. Studies have shown that taking collagen supplements can reduce the stiffness of the arteries and increase levels of "good" HDL cholesterol in the body. This means it can help reduce the risk of developing heart disease. The results of the present study indicate that the collagen tripeptide CTP contributes to the prevention and treatment of atherosclerosis in healthy humans.
https://www.yahoo.com/lifestyle/heart-boosting-benefits-collagen-may-201246995.html?guccounter=1&guce_referrer=aHR0cHM6Ly93d3cuZ29vZ2xlLmNvbS8&guce_referrer_sig=AQAAAKSBNbsLBCz_d12PmyVD98N6aAJV3e (2) 022).---- ----
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429168/ (2017).--