Research suggests that BPA and similar chemicals can disrupt the endocrine system, increasing your risk for conditions such as hypertension and diabetes.
BPA exposure affects various structural and molecular changes of the brain, promoting oxidative stress, changing the expression levels of several crucial genes and proteins, destructive effects on neurotransmitters, excitotoxicity and neuroinflammation, impaired blood-brain barrier function, neuronal damage, effects of apoptosis, altered intracellular Ca 2+ homeostasis, increased reactive oxygen species, promoted apoptosis and release of intracellular lactate dehydrogenase, decreased axon length, microglial DNA damage, astrogliosis and significantly reduced myelination . Additionally, exposure to BPA increases the risk of developing neurological diseases, including neurovascular (e.g., stroke) and neurodegenerative diseases (e.g., Alzheimer's and Parkinson's). Furthermore, epidemiological studies demonstrated that the adverse effects of BPA on the neurological development of children contributed to the emergence of serious neurological diseases such as attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder (ASD), depression, emotional problems, anxiety and cognitive problems. disorders. In summary, exposure to BPA compromises human health, promoting the development and progression of neurological disorders. More research is required to fully understand how BPA-induced neurotoxicity affects human health.
BPA exposure affects various structural and molecular changes of the brain, promoting oxidative stress, changing the expression levels of several crucial genes and proteins, destructive effects on neurotransmitters, excitotoxicity and neuroinflammation, impaired blood-brain barrier function, neuronal damage, effects of apoptosis, altered intracellular Ca 2+ homeostasis, increased reactive oxygen species, promoted apoptosis and release of intracellular lactate dehydrogenase, decreased axon length, microglial DNA damage, astrogliosis and significantly reduced myelination . Additionally, exposure to BPA increases the risk of developing neurological diseases, including neurovascular (e.g., stroke) and neurodegenerative diseases (e.g., Alzheimer's and Parkinson's). Furthermore, epidemiological studies demonstrated that the adverse effects of BPA on the neurological development of children contributed to the emergence of serious neurological diseases such as attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder (ASD), depression, emotional problems, anxiety and cognitive problems. disorders. In summary, exposure to BPA compromises human health, promoting the development and progression of neurological disorders. More research is required to fully understand how BPA-induced neurotoxicity affects human health.
https://link.springer.com/article/10.1007/s00204-023-03614-0 (2023)
https://www.sciencedirect.com/science/article/abs/pii/S0166432823005582 (2023).--