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Highly relevant report. The decline in abundance of L. reuteri in humans in recent decades correlates with an increase in the incidence of inflammatory diseases. Modulation of the gut microbiota by ingesting probiotic strains of L. reuteri could be a promising preventive and therapeutic approach against many diseases and disorders.----

1) Research supporting the application of various strains of L. reuteri in the treatment of common diseases of the digestive system, including infantile colic, diarrhea, constipation, functional abdominal pain, Helicobacter pylori infection, inflammatory bowel disease, diverticulitis, colorectal cancer, and liver diseases.------

2) L. reutero can control body weight and obesity, improve insulin sensitivity and glucose homeostasis, increase intestinal integrity and immunomodulation, and attenuate liver disorders. ----

3) L. reuteri is capable of inhibiting the colonization of pathogenic microbes and remodeling the composition of the commensal microbiota in the host.-----

4) L. reuteri may benefit the host's immune system. Reduce the production of proinflammatory cytokines while promoting the development and function of regulatory T cells. ----

5) Colonization of L. reuteri can reduce microbial translocation from the intestinal lumen to tissues, preventing inflammation. ----

6) L. reuteri decreases intestinal pH and increases short chain fatty acids, such as butyric acid, which is essential for intestinal health.----

7) L-reuteri improves tolerance in your diet, promoting the absorption of nutrients, strengthening your defenses.----

8) Lactobacillus reuteri prevents post-antibiotic bone loss by reducing intestinal dysbiosis and preventing barrier disruption----

9) The use of L. reuteri as an adjunct to non-surgical periodontal treatment can produce significantly better clinical results.-----

L. reuteri strain may help colic symptoms, improve digestion, and reduce the risk of premature birth. The probiotic L. reuteri can have a positive impact on gastrointestinal function and relieve colic symptoms in three ways; strengthening the mucosal barrier, increasing gastric motility and balancing the intestinal microbiota. Additionally, L. reuteri is the only probiotic that has been repeatedly shown in studies to reduce crying time in babies with colic.

https://www.frontiersin.org/articles/10.3389/fmicb.2018.00757/full (2018)----

https://www.sciencedirect.com/science/article/pii/S0965229921001229 (2021)----

https://asbmr.onlinelibrary.wiley.com/doi/full/10.1002/jbmr.3635 (2019)----

https://pubs.rsc.org/en/content/articlelanding/2021/fo/d1fo02517a/unauth (2021)---

https://www.mdpi.com/2076-2607/10/3/522 (2022)----

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10471993/ (2023)---

https://asbmr.onlinelibrary.wiley.com/doi/full/10.1002/jbm4.10805 (2023)----

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613642/ (2023)---

https://www.sciencedirect.com/science/article/pii/S175646462300405X (2023)---

https://www.mdpi.com/2076-2607/11/6/1449 (2023)---

https://onlinelibrary.wiley.com/doi/full/10.1111/hel.13017 (2023)---

https://bmcgastroenterol.biomedcentral.com/articles/10.1186/s12876-023-02778-4 (2023)---

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