A review article, recently published in the journal Phytotherapy Research, definitively shows that curcumin is, in fact, a potentially (and mostly proven) very powerful therapeutic in the treatment of both COVID and prion disease caused by COVID-19. “vaccines” and zoonotic viruses, Vitamin D and curcumin are two highly relevant supplements.
Turmeric has been used to treat and prevent many different conditions such as inflammation, diabetes, cough, liver disease, arthritis, diarrhea, gastric, skin and blood disorders in ancient Indian and traditional medicine for several hundred years. Researchers found that C. longa exhibits a broad spectrum of pharmacological actions, such as anti-inflammatory, antidiabetic, antioxidant, hepatoprotective, antimicrobial, antiosteoarthritis, neuroprotective, antiaging, antidiarrheal, wound healing, and antidepressant. and anticancer activity. Extensive research over the past two decades suggests that curcuminoids belonging to the diferuloylmethane class of natural products, the main components of turmeric (Curcuma longa), interfere with multiple cell signaling pathways, providing support for the potential role of curcumin in the modulation of carcinogenesis. These pathways include the following:---
1) Cell cycle.---
2) Apoptosis ---
3) Proliferation ---
4) Survival ---
5) Angiogenesis ---
6) 'Metastasis ---
7) 'Inflammation---
Reviews have uncovered the multifaceted potential of curcumin as an immunomodulator, radioprotective drug, anticancer, and much more.
The species Curcuma longa L (CUR)., contains several active ingredients including volatile oils (i.e., α-zingiberene, curlone and α-turmerone) and mainly (95% of the standardized extract) three curcuminoids.
In vitro and in vivo studies have shown that CUR can inhibit the growth of breast, colon, lung, gastrointestinal tract, liver, prostate, kidney, pancreas, leukemia, osteosarcoma, melanoma and brain cancer. Furthermore, CUR is capable of enhancing the anticancer effects of both radiotherapy and chemotherapeutic agents, showing low toxicity to normal cells.
In these studies, a systematic review was conducted to estimate the effect of turmeric or curcumin supplementation on prostate diseases. Curcumin/turmeric supplementation beneficial effects on prostate-specific antigen (PSA) levels as well as on markers of oxidative stress, sensation of incomplete emptying of the bladder, frequency of urination, intermittency. , urgency, weak stream, effort and nocturia. Curcumin also exhibited prostate tumor growth inhibitory properties,
Piperine enhances the inhibitory effect of curcumin on tumor progression by improving its administration and therapeutic activity. Triple cannabinoid treatment showed synergism in terms of exhibiting antitumor effects
A review article, recently published in the journal Phytotherapy Research, definitively shows that curcumin is, in fact, a potentially (and mostly proven) very powerful therapeutic in the treatment of both COVID and prion disease caused by COVID-19. “vaccines” and zoonotic viruses, Vitamin D and curcumin are two highly relevant supplements.
https://onlinelibrary.wiley.com/doi/10.1002/ptr.8119 (2024).--
Turmeric has been used to treat and prevent many different conditions such as inflammation, diabetes, cough, liver disease, arthritis, diarrhea, gastric, skin and blood disorders in ancient Indian and traditional medicine for several hundred years. Researchers found that C. longa exhibits a broad spectrum of pharmacological actions, such as anti-inflammatory, antidiabetic, antioxidant, hepatoprotective, antimicrobial, antiosteoarthritis, neuroprotective, antiaging, antidiarrheal, wound healing, and antidepressant. and anticancer activity. Extensive research over the past two decades suggests that curcuminoids belonging to the diferuloylmethane class of natural products, the main components of turmeric (Curcuma longa), interfere with multiple cell signaling pathways, providing support for the potential role of curcumin in the modulation of carcinogenesis. These pathways include the following:---
1) Cell cycle.---
2) Apoptosis ---
3) Proliferation ---
4) Survival ---
5) Angiogenesis ---
6) 'Metastasis ---
7) 'Inflammation---
Reviews have uncovered the multifaceted potential of curcumin as an immunomodulator, radioprotective drug, anticancer, and much more.
The species Curcuma longa L (CUR)., contains several active ingredients including volatile oils (i.e., α-zingiberene, curlone and α-turmerone) and mainly (95% of the standardized extract) three curcuminoids.
In vitro and in vivo studies have shown that CUR can inhibit the growth of breast, colon, lung, gastrointestinal tract, liver, prostate, kidney, pancreas, leukemia, osteosarcoma, melanoma and brain cancer. Furthermore, CUR is capable of enhancing the anticancer effects of both radiotherapy and chemotherapeutic agents, showing low toxicity to normal cells.
https://www.ncbi.nlm.nih.gov/books/NBK568018/ (2021)
https://www.frontiersin.org/articles/10.3389/fnut.2024.1399888/full (2024).--
https://www.igi-global.com/chapter/anticancer-properties-of-curcuma-longa/341957 (2024).--
https://ajabtr.smartsociety.org/wp-content/uploads/2024/03/Turmeric-and-Cancer-Prevention-Rohan1.pdf (2024).--
https://www.mdpi.com/2075-1729/13/2/261 (2023)-
https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/abs/10.1002/cbf.3911 (2924).--
https://www.frontiersin.org/articles/10.3389/fphar.2023.1102581/full (2023).---
https://onlinelibrary.wiley.com/doi/full/10.1002/ptr.8220 (2024).--
In these studies, a systematic review was conducted to estimate the effect of turmeric or curcumin supplementation on prostate diseases. Curcumin/turmeric supplementation beneficial effects on prostate-specific antigen (PSA) levels as well as on markers of oxidative stress, sensation of incomplete emptying of the bladder, frequency of urination, intermittency. , urgency, weak stream, effort and nocturia. Curcumin also exhibited prostate tumor growth inhibitory properties,
https://link.springer.com/chapter/10.1007/978-3-030-56153-6_20 (2021)
https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2024.1379389/full (2024).--
Piperine enhances the inhibitory effect of curcumin on tumor progression by improving its administration and therapeutic activity. Triple cannabinoid treatment showed synergism in terms of exhibiting antitumor effects
https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2023.1145666/full (2023).--