Your health today is the result of a complex interplay of factors, and your health choices will eventually impact the health of your children and grandchildren.
We are genetically designed to heal. Physiology is designed to overcome you and make you stronger. The disease is mostly the result of living a lifestyle that is incompatible with life and longevity. Even deadly diseases can be resolved with lifestyle medicine. Epigenetics is a fascinating process by which the body turns genes on and off through metabolism. Unlike genetic modifications, epigenetic changes are reversible, because they do not affect the DNA sequence but rather involve alterations in the structure of chromatin and the accessibility of DNA for gene regulation.
Epigenetic factors are influenced directly and indirectly by the presence or absence of key nutrients in the diet, as well as by exposure to chemicals, pathogens and other environmental influences, as well as emotions. Simply put, the lifestyles and environmental exposures of us and our ancestors directly affect our DNA and its expression.
Prenatal stress can affect DNAm in perinatal tissues, such as umbilical cord blood and placenta. This can have consequences on the child's health, such as stress reactivity, neurobehavioral problems, and psychiatric disorders.
This review focuses on various stress factors that affect aging including oxidative stress, genotoxic stress, inflammatory stress and metabolic stress and their epigenetic regulation.
Nutrition affects the epigenetic mechanisms of the pathogenesis of many diseases, including infertility. Infertility is associated with epigenetic mechanisms, nutrients, bioactive components and many other factors. Vitamins B12, D and B6, biotin, choline, selenium, zinc, folic acid, resveratrol, quercetin and others are involved in fertility.
This review provides a brief study of the role of vitamins as epigenetic modulators or nutraceuticals, emphasizing. Vitamins A, B, C, D, E, K and A have been shown to affect the DNA methylation process.
Vitamin C can act as a regulator of kinases, such as MAPK and p38, or controlling the activation of the NF-kB pathway, generating chronic responses related to changes in gene expression.
These reviews present a broad overview including the epigenetic effects of all 13 vitamins and vitamin B and B12 in terms of DNA methylation, histone modification, and ncRNA expression. The most debated fields of vitamin epigenetics are tumor suppression, organ protection, and treatment of neurodegeneration.
We are genetically designed to heal. Physiology is designed to overcome you and make you stronger. The disease is mostly the result of living a lifestyle that is incompatible with life and longevity. Even deadly diseases can be resolved with lifestyle medicine. Epigenetics is a fascinating process by which the body turns genes on and off through metabolism. Unlike genetic modifications, epigenetic changes are reversible, because they do not affect the DNA sequence but rather involve alterations in the structure of chromatin and the accessibility of DNA for gene regulation.
Epigenetic factors are influenced directly and indirectly by the presence or absence of key nutrients in the diet, as well as by exposure to chemicals, pathogens and other environmental influences, as well as emotions. Simply put, the lifestyles and environmental exposures of us and our ancestors directly affect our DNA and its expression.
https://learn.genetics.utah.edu/content/epigenetics/ ------
https://www.cshlpress.org/pdf/sample/2014/epigenetics2/EPIChap.pdf .---
https://europepmc.org/article/med/20944598 .---
https://www.rupahealth.com/post/what-is-methylation-an-introduction-to-its-role-in-health-and-disease-for-functional-medicine-practitioners (2024).---
Prenatal stress can affect DNAm in perinatal tissues, such as umbilical cord blood and placenta. This can have consequences on the child's health, such as stress reactivity, neurobehavioral problems, and psychiatric disorders.
https://link.springer.com/article/10.1186/s13148-024-01635-9 (2024).--
This review focuses on various stress factors that affect aging including oxidative stress, genotoxic stress, inflammatory stress and metabolic stress and their epigenetic regulation.
https://www.cell.com/molecular-cell/fulltext/S1097-2765(23)00809-2?dgcid=raven_jbs_etoc_email (2024).--
Nutrition affects the epigenetic mechanisms of the pathogenesis of many diseases, including infertility. Infertility is associated with epigenetic mechanisms, nutrients, bioactive components and many other factors. Vitamins B12, D and B6, biotin, choline, selenium, zinc, folic acid, resveratrol, quercetin and others are involved in fertility.
https://www.ingentaconnect.com/content/ben/cwhr/2024/00000020/00000005/art00008 (2024).--
This review provides a brief study of the role of vitamins as epigenetic modulators or nutraceuticals, emphasizing. Vitamins A, B, C, D, E, K and A have been shown to affect the DNA methylation process.
https://pubmed.ncbi.nlm.nih.gov/36200195/ (2023).---
https://hdrilab.com/wp-content/uploads/2023/08/role_of_b_vitamins_in_biological_methylation.pdf (2024).--
Vitamin C can act as a regulator of kinases, such as MAPK and p38, or controlling the activation of the NF-kB pathway, generating chronic responses related to changes in gene expression.
https://www.mdpi.com/2076-3921/10/2/215 (2023).--
These reviews present a broad overview including the epigenetic effects of all 13 vitamins and vitamin B and B12 in terms of DNA methylation, histone modification, and ncRNA expression. The most debated fields of vitamin epigenetics are tumor suppression, organ protection, and treatment of neurodegeneration.
https://www.researchgate.net/profile/Shujie-Huang-2/publication/327793409_Epigenetic_Effects_of_the_13_Vitamins/links/5bada68792851ca9ed2b8eb5/Epigenetic-Effects-of-the-13-Vitamins.pdf (2019).--
https://www.rupahealth.com/post/the-role-of-b-vitamins-in-methylation-processes-clinical-applications-and-dosage-guidelines (2024).--
https://academic.oup.com/nutritionreviews/article/78/8/647/5715575?login=false (2024).--
This review focuses on the epigenetic action of vitamins to induce the onset and progression of colorectal cancer.
https://academic.oup.com/nutritionreviews/article/81/4/455/6677260?login=false (2023),.--