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Tobacco and the taxes that originated in the State collection have always been the object of a defense of the interests of the tobacco industry and governments. E-cigs (EC) constitute a continuity of benefits for tobacco companies, after advertising that warned about the health problems of smoking. Not only does it continue the business, but it creates an addiction in young people to smoke again. The tobacco industry's interest in e-cigs is clear: today, most brands offer products of this type. In the European Union, each country can make certain decisions to regulate their use, and several nations prohibit the use of electronic cigarettes in public buildings and children's areas.

An integrative review reported that conventional cigarettes have deleterious effects on the health of chronic users, as well as passive smokers.

https://academic.oup.com/ntr/advance-article-abstract/doi/10.1093/ntr/nty221/5139734 (2018).---

https://repositorio.animaeducacao.com.br/handle/ANIMA/31639 (2022).---

Emerging results now describe risks related to the development of respiratory and cardiovascular diseases and even cancer. We report how e-cigarette aerosol exposure induces mitochondrial stress/toxicity, DNA breaks/fragmentation following the same pathological pathways triggered by tobacco smoke, including dysregulation of the molecular signaling axis associated with cancer progression and migration. cell phone. Fertility and pregnancy risks, as well as cardiovascular risks associated with e-cigarette use, have also been reported. Electronic cigarettes cause an increase in probing depth, bone loss, and the level of IL-1β, one of the bone destruction mediators in the tissues around the implant, and a decrease in bleeding on probing. EC use was independently and significantly associated with increased odds of life stress and an indication of poorer quality of life.

Inhalation alters gene expression, cardiovascular function, decreased heart rate, and elevated blood pressure and can lead to increased inflammation, organ damage, and cardiorenal and liver disease in experiments. Chronic exposure to e-cigarette aerosols during early development causes vascular dysfunction and growth deficiencies in offspring.

Most e-CIGS liquids, in addition to nicotine, may contain glycerol, flavors and a wide variety of other substances such as tin, lead, nickel, chromium, nitrosamines with carcinogenic potential. The average nicotine is about 15 mg/ml, but can reach 36, it is related to cardiovascular events, delayed fetal development, spontaneous rabortion, premature birth and changes in brain development of young people and adolescents. In children, whose smoking threshold is much lower than in adults. There are already cases of children who became poisoned after using their parents' e-cigarettes. The study's health risks are evident. It was determined that it causes cytotoxicity to stem cells, in relation to the aromas used, which aggravates the problem in pregnant women. Propylene glycol and glycerin can cause eye and respiratory irritation and prolonged or repeated inhalation in industrial environments can affect the central nervous and immune system. The aerosol produced contains formaldehyde and acetaldehyde, which are carcinogenic.

https://www.sciencedirect.com/science/article/abs/pii/S1043661822002602 (2022).--

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8960730/ (2022).--

https://www.sciencedirect.com/science/article/abs/pii/S1931524419300027 (2019).--

https://escholarship.org/content/qt31r375hp/qt31r375hp.pdf (2022).--

https://www.nature.com/articles/s41467-022-33203-1 (2022).--

https://link.springer.com/article/10.1007/s00431-024-05499-2 (2024).---

https://www.sciencedirect.com/science/article/pii/S0300571224000538 (2024).---

https://www.peertechzpublications.org/articles/ATTE-8-116.pdf (2024).---

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