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An article that shows us that the combination of stimulant substances can cause dramatic results. In this extensive review of the literature, the consequences of energy drinks include cardiac arrhythmias, neurological and behavioral changes, acute inflammation of organs (including the liver, stomach, pancreas and kidneys), and autoimmune disorders. Their long-term effects are not yet known and they can cause psychiatric pathologies or the worsening of cardiac disorders. The results show an inflammatory response associated with oxidative stress, local gliosis and elevated levels of IL-1, TNF-1, iNOS, reactive oxygen species and peroxidation.

Exposure to alcohol in combination with energy drinks prolongs the duration of motor impairment, total white blood cell count, plasma potassium, calcium, kidney function, liver enzymes and plasma triglycerides, increased locomotor activity, and increased levels of anxiety.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535526/ (2023).--

In this review, excessive caffeine consumption among adolescents can cause disorders such as systolic high blood pressure, agitation, nausea, anxiety, osteoporosis, palpitations, poor quality of sleep and stomach ulcers. Taurine prevents obesity among children, causes positive effects on oxidative stress and inflammation in adolescents, and affects exercise capacity in athletes. Significant increases in serum levels of uric acid, creatinine, liver enzymes bilirubin caused by chronic intake of energy drinks indicated different degrees of injury to the kidneys and liver. Chronic intake of RDAs in adolescents was associated with a reduced DNA damage, attenuated inflammation, prevented mitochondrial dysfunction, protection against telomerase deficiency and slowing cellular senescence.

https://www.mdpi.com/2079-9284/11/1/12 (2024).--

Taurine is a semi-essential amino acid. The body depends on taurine, especially in the first years of life. Its deficiency can affect the nervous system and muscles. Taurine levels in various tissues decrease as we age.

Taurine contributes to weight control, stronger bones and muscles. Taurine also appeared to improve control of blood sugar levels, improve immune function, and reduce inflammation.

Taurine slows aging at the cellular level, reducing DNA damage and other markers of aging. It could even improve the cells' perception of nutrients, boost mitochondria, and reduce inflammation.

Taurine supplementation slowed key markers of aging, such as increased DNA damage, telomerase deficiency, impaired mitochondrial function, and cellular senescence. Loss of taurine in humans was associated with aging-related diseases, and concentrations of taurine and its metabolites increased in response to exercise. Exercise increases taurine levels and slows the aging process.

https://www.science.org/doi/abs/10.1126/science.abn9257 (2023).--

.---https://www.science.org/doi/10.1126/science.abn9257 (2023)

In these reviews, a low dose of taurine (0.05 g) before performing strength-building exercises can decrease muscle fatigue and increase enzymatic antioxidants. Taurine supplementation significantly increased SOD and GPX. Taurine has antioxidant effects against oxidative stress induced by resistance exercise and lipid peroxidation. Taurine activates the AKT-mTOR axis to restore muscle mass and contractile strength in human models

https://link.springer.com/article/10.1007/s40279-018-0896-2 (2018).---

https://www.frontiersin.org/articles/10.3389/fphys.2021.700352/full (2021).----

https://www.science.org/doi/abs/10.1126/science.adi3025 (2023).---

https://www.magiran.com/paper/2575766?lang=en (2023).---

https://journals.biologists.com/dmm/article/17/4/dmm050540/347006 (2024).--

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