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The importance of knowing what emerging contaminants are is that every day we face them in pharmaceuticals, household cleaning and personal care products; even in food. It is estimated that a source of contamination is untreated urban wastewater and effluents from wastewater treatment plants, since these substances end up being released into surface water, into the soil or, in very specific cases, reinjected into the aquifer as well as medical.

Studies reveal that the main effects of exposure of different fish species to estrogenic compounds include alteration of sexual development, as well as changes in mating behavior, reduction of reproductive success and alterations of the endocrine system. These changes can be expressed later in the life cycle or even in future generations. This affects humans who have reported low sperm count and deterioration in male reproductive health and, on the other hand, breast cancer in women, as a consequence of increasing exposure to these compounds.

Pharmaceutical industries, hospitals and treatment plants oppose legislation for in-situ disposal because it involves high costs in treatments to eliminate harmful compounds before they are released into the environment. However, on the other side of the reflection are all the harmful effects that its presence in the environment can cause, so a delay in awareness could cause a time to come when it is too late.

DES is a synthetic estrogen that has been used as an agent to prevent miscarriage in pregnant women. Since then, adverse effects of DES exposure have been detected in exposed mothers and especially in their daughters, known as DES daughters. The most pronounced effects seen in DES daughters include structural abnormalities in the reproductive organs, adverse reproductive outcomes, and cancers of the reproductive system, including the vagina, cervix, and breast.

Bisphenol A (BPA) is a synthetic estrogen found in numerous consumer products and is widely exposed to humans and wildlife. It can cause infertility, various changes in offspring, development and function of reproductive organs, and behavior. BPA also affects the metabolic, thyroid hormone, and androgen systems. Infertility is a problem that affects one in six couples, which represents approximately 15% of the population who wants to start a family. In 30% of infertile couples, the male factor is one of the main causes

Bisphenol A (BPA) is associated with several chronic metabolic diseases including obesity and diabetes. Obesity increases the risk of associated diseases, such as infertility. type 2 diabetes mellitus, dyslipidemia, cholelithiasis, hypertension, coronary heart disease, stroke, endometrial and breast cancer, premature aging and neurodegenerative diseases. It is estimated that complications derived from obesity contribute to more than 4,000,000 deaths per year worldwide, representing 7% of mortality from all causes.

https://www.sciencedirect.com/science/article/abs/pii/S0166445X11002529 (2012).--

https://www.sciencedirect.com/science/article/abs/pii/S0166445X23000528 (2023).--

https://www.sciencedirect.com/topics/agricultural-and-biological-sciences/synthetic-estrogens (2014).--

https://www.sciencedirect.com/science/article/abs/pii/S1521693423001013 (2024).--

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10042660/ (2023)

https://onlinelibrary.wiley.com/doi/abs/10.1111/obr.13738 (2024).--

https://journals.sagepub.com/doi/full/10.1177/1559325820916949 (2020).--

The European Commission began a consultation in February 2024 on a draft proposal to phase out the use of the controversial chemical bisphenol A.

https://www.euractiv.com/section/agriculture-food/news/eu-commission-moves-to-ban-bisphenol-a-in-food-packaging/ (2024).-

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Avoiding toxins is nearly impossible. Reducing is possible but how much and to what effect for each individual person I don't think can be quantified. I do what I can and let it go. BHRT has enabled me to work, sleep, and have better relationships. Estrogen is made by all women naturally and is not a carcinogen or else every woman in the planet would have cancer. The human race could not continue. Can there be environmental things to make it go sideways, sure. Would I use progestin? No. Everyone has to make a decision as to what medical interventions they want to utilize. We all just need truthful info to decide. I appreciate Dr Mercola and respect him but he is off on this and I am cool with that. I don't adapt everything I read on his site nor have to. I have a mind of my own and a holistic practitioner I see.

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Thank you! What are your thoughts on HRT?

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Use compounded BHRT if you wish to give it a shot. Everyone is different. Some need just a tiny bit and some need more. If you do go to a holistic practitioner who is experienced and will monitor you. I heard a woman asked how long she would use it and she said until a nail is in her coffin or she is burned. Dr. David Brownstein uses testosterone and progesterone. He prescribed BHRT and has done so for years. He is in West Bloomfield, MI. If you are not in Michigan do a teledoc visit. He expensive. I can tell you no allopathic doc will prescribe them. You may find one that will use HRT...maybe.

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I agree with Allie’s comment. BHRT for post menopausal women is beneficial because it supports the gut, is Immuno-protective, brain protective, supports bone density levels, and many autoimmune issues arise during the post menopause years after estrogen drops. I agree that xenoestrogenic and synthetic estrogen compounds that bombard us are harmful to our health and should be reduced. However, I also believe Dr Mercola needs to specify that for women of child-bearing age, excess estrogen is problematic. But, for post-menopause women bioidentical estrogen supplementation can be beneficial as long as it is balanced with the progesterone he speaks of. I feel infinitely better taking bioidentical estrogen and progesterone now that I am in menopause. Please be sure to make this distinction because you are doing a disservice to post menopausal women!!! This isn’t like you Dr Mercola!!

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Flaxseed is almost 20% MORE estrogenic than soy!!

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I agree with Allie’s comment. BHRT for post menopausal women is beneficial because it supports the gut, is Immuno-protective, brain protective, supports bone density levels, and many autoimmune issues arise during the post menopause years after estrogen drops. I agree that xenoestrogenic and synthetic estrogen compounds that bombard us are harmful to our health and should be reduced. However, I also believe Dr Mercola needs to specify that for women of child-bearing age, excess estrogen is problematic. But, for post-menopause women bioidentical estrogen supplementation can be beneficial as long as it is balanced with the progesterone he speaks of. I feel infinitely better taking bioidentical estrogen and progesterone now that I am in menopause. Please be sure to make this distinction because you are doing a disservice to post menopausal women!!! This isn’t like you Dr Mercola!!

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I am 67, on Prozac. My psychiatrist states I should not go off it. All this info about serotonin and estrogen has me confused.

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