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In connection with Dr. Mercola's revealing article. Scientific studies have shown a possible link between PFAS exposure and health problems such as higher cholesterol levels, decreased immune system response, thyroid changes, high blood pressure, neurotoxic effects, effects on the liver and risk of certain cancers.

Exposure to high levels of PFAs affects the immune system. A National Toxicology Program review found that exposure to perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) is an immunological risk to humans based on a high level of evidence that PFOA and PFOS suppressed the immune response. antibodies. In general, persistent organic pollutants are characterized by their wide distribution, persistence and bioaccumulation. They have different carcinogenic mechanisms, which include interference with the cell proliferation cycle, alteration of epigenetic inheritance, promotion of oxidative stress, alteration of energy metabolism. and the impairment of immune function.

https://www.healthychildren.org/English/safety-prevention/all-around/Pages/Limiting-Childrens-Exposure-to-Forever-Chemicals.aspx (2023).----

https://www.aap.org/en/patient-care/environmental-health/promoting-healthy-environments-for-children/perfluoroalkyl-and-polyfluoroalkyl-substances/ (2023).----

https://www.jeom.org/en/article/doi/10.11836/JEOM23370 (2024).--

Perfluoroalkyl substances (PFAS) are persistent chemicals capable of crossing the placenta and entering breast milk. Evidence suggests that exposure to PFAS can affect brain development. In multiple linear regression analyzes conducted among 967 mother-infant pairs, a doubling of maternal PFOS and PFNA concentrations was associated with a lower Full Scale Intelligence Quotient score.

https://academic.oup.com/aje/article-abstract/192/9/1522/7146879?login=false (2023).—

Exposure to perfluoroalkyl substances (PFAS) during pregnancy was linked to higher body mass indexes and an increased risk of obesity in children, according to a new Environmental Health Perspectives study led by researchers at Brown University.

https://www.brown.edu/news/2023-06-07/pfas-obesity (2023)

This USGS map shows the amount of PFAS detected in tap water samples from select sites across the country. The findings are based on a USGS study of samples taken between 2016 and 2021 from public and private supplies at 716 locations. The map does not represent the only places in the US with PFAS.

Most exposure was observed near urban areas and potential sources of PFAS. This included the Great Plains, Great Lakes, East Coast, and Central and Southern California regions.

https://www.usgs.gov/news/national-news-release/tap-water-study-detects-pfas-forever-chemicals-across-us (2023)

The incidence of colorectal cancer (CRC) continues to increase worldwide and is expected to reach 2.2 million new cases and cause approximately 1.1 million deaths by the end of the decade.

This study found a positive association between serum PFAS mixtures and the amount of MLN in CRC patients. These results provided evidence that PFAS exposure may affect CRC promotion.

https://www.sciencedirect.com/science/article/abs/pii/S0013935123023332 (2024).--

In this research, ovarian cancer or uterine cancer had higher concentrations of perfluoroalkyl and polyfluoroalkyl substances (PFAS) and phenols in the blood. The results have just been published in the Journal of Exposure Science and Environmental Epidemiology. "These findings show that PFAS and phenols are environmental risk factors for cancer risk in women," said Max Aung, PhD.

https://keck.usc.edu/news/exposure-to-certain-chemicals-raises-the-odds-of-a-prior-cancer-diagnosis-in-women/ (2023)

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