Interesting and innovative article. Considerations on thermoregulatory responses of young and elderly adults. bodily. Data from World Population Prospects says one in six people in the world will be over 65, and the number of people over 80 will triple to 426 million in 2050. The National Institute on Aging and governments of several Nations also warn about the effects of heat and cold waves on older people, such as heatstroke and hypothermia. This study aims to investigate age differences in thermoregulatory responses.
Thermoregulation is a physiological mechanism by which an organism maintains its body temperature within a certain range through a negative feedback loop. The hypothalamus in the brain controls this mechanism, which is a representative example of homeostasis, the body's ability to maintain its condition at a certain level in response to a changing external environment. As shown in Fig. 1(A), the thermoregulatory mechanism consists of three basic components.
Older people prefer a room temperature similar to that of young people, but lack the ability to recognize and adjust room temperature. That is, elderly people are more likely to be exposed to an inadequate thermal environment. As people age, they undergo a variety of physical changes, including decreased cardiac blood output, loss of control over sweating capacity, decreased muscle mass/basal metabolic rate/thermal sensitivity, and increased body fat percentage.
Older people run various risks due to increased temperature. -----1) Aging affects cardiac function, which plays an important role in thermoregulation. It also reduces cardiac output and increases systemic vascular resistance, decreasing cutaneous blood flow, which is vital for thermoregulation.
-----2) aging directly affects thermoregulatory mechanisms, such as vasoconstriction, vasorelaxation or muscle tremors. Furthermore, elderly people have less contraction of blood vessels and less ability to sense cooling in a cold environment and are subject to decreased sweat secretion, skin blood flow, and cardiac output in a cold environment. warm. 3) older people generally have weaker homeostasis. For example, blood glucose levels generally maintain homeostasis due to insulin and glucagon secreted by the adrenal glands. However, because aging reduces the body's ability to produce or use insulin and glucagon effectively, older people have a relatively higher risk of developing type 2 diabetes.
In summary:
1) Age differences in thermoregulation was statistically significant.
2) Elderly individuals have insensitive thermoreceptors with smaller overshooting.
3) Elderly individuals' recovery and stabilization time took longer.
4) Types and directions of temperature ramp have impact on thermoregulatory responses.
When a theory is evaluated, any facts that appear to not support the theory are very important to consider. The observations made by Weston Price and Vilhjarmur Stefansson do not appear to support the theory that a low carbohydrate diet is bad for human health. I have gone down this Ray Peat rabbit hole . . . however not everything appears to line up with the facts that I have read over time, Confirmation bias? . . . let's find out.
Interesting and innovative article. Considerations on thermoregulatory responses of young and elderly adults. bodily. Data from World Population Prospects says one in six people in the world will be over 65, and the number of people over 80 will triple to 426 million in 2050. The National Institute on Aging and governments of several Nations also warn about the effects of heat and cold waves on older people, such as heatstroke and hypothermia. This study aims to investigate age differences in thermoregulatory responses.
Thermoregulation is a physiological mechanism by which an organism maintains its body temperature within a certain range through a negative feedback loop. The hypothalamus in the brain controls this mechanism, which is a representative example of homeostasis, the body's ability to maintain its condition at a certain level in response to a changing external environment. As shown in Fig. 1(A), the thermoregulatory mechanism consists of three basic components.
Older people prefer a room temperature similar to that of young people, but lack the ability to recognize and adjust room temperature. That is, elderly people are more likely to be exposed to an inadequate thermal environment. As people age, they undergo a variety of physical changes, including decreased cardiac blood output, loss of control over sweating capacity, decreased muscle mass/basal metabolic rate/thermal sensitivity, and increased body fat percentage.
Older people run various risks due to increased temperature. -----1) Aging affects cardiac function, which plays an important role in thermoregulation. It also reduces cardiac output and increases systemic vascular resistance, decreasing cutaneous blood flow, which is vital for thermoregulation.
-----2) aging directly affects thermoregulatory mechanisms, such as vasoconstriction, vasorelaxation or muscle tremors. Furthermore, elderly people have less contraction of blood vessels and less ability to sense cooling in a cold environment and are subject to decreased sweat secretion, skin blood flow, and cardiac output in a cold environment. warm. 3) older people generally have weaker homeostasis. For example, blood glucose levels generally maintain homeostasis due to insulin and glucagon secreted by the adrenal glands. However, because aging reduces the body's ability to produce or use insulin and glucagon effectively, older people have a relatively higher risk of developing type 2 diabetes.
In summary:
1) Age differences in thermoregulation was statistically significant.
2) Elderly individuals have insensitive thermoreceptors with smaller overshooting.
3) Elderly individuals' recovery and stabilization time took longer.
4) Types and directions of temperature ramp have impact on thermoregulatory responses.
https://www.sciencedirect.com/science/article/abs/pii/S0360132323007874 (2023).---
When a theory is evaluated, any facts that appear to not support the theory are very important to consider. The observations made by Weston Price and Vilhjarmur Stefansson do not appear to support the theory that a low carbohydrate diet is bad for human health. I have gone down this Ray Peat rabbit hole . . . however not everything appears to line up with the facts that I have read over time, Confirmation bias? . . . let's find out.