5 Comments
User's avatar
Guillermou's avatar

Great information from this article by Dr. Mercola. I love organic goat yogurt, which also provides pentadecanoic acid, also known as C15:0 or simply C15. It is a saturated fatty acid with 15 carbon atoms and no double bonds. Good sources of C15:0 are full-fat dairy products, ruminant meat, and fatty fish. C15:0 may be a potentially valuable nutrient for overall health. Dr. Mercola has referenced this fatty acid. https://articles.mercola.com/sites/articles/archive/2023/12/26/dairy-fat-benefits.aspx (2023).-

Together with C15:0's previously demonstrated abilities to target longevity pathways, hallmarks of aging, biomarkers of the rate of aging, and core components of type 2 diabetes, heart disease, cancer, and nonalcoholic fatty liver disease, our results support C15:0 as an essential nutrient with activities equivalent to or superior to those of leading candidate compounds for enhancing longevity. C15:0 deficiencies (≤0.2% of total circulating fatty acids) may increase susceptibility to ferroptosis, dysmetabolic iron overload syndrome, type 2 diabetes, cardiovascular disease, and NAFLD. Furthermore, evidence is provided that C15:0 supplementation can reverse the described C15:0 deficiency syndrome, including key components of ferroptosis. Given the decreased dietary intake of C15:0, especially among younger generations, comprehensive studies are required to understand the potential magnitude of Cell Fragility Syndrome in different populations.

1) Anti-inflammatory properties. C15:0 fatty acids had significant anti-inflammatory effects, reducing markers such as MCP-1, a protein that attracts immune cells.

2) Improves cardiometabolic health. In a larger observational study exploring data from over 15,000 people, higher blood levels of odd-chain fatty acids, including C15:0, were associated with lower levels of LDL cholesterol, triglycerides, apolipoprotein B, and other cardiovascular risk markers.

3) Protection of liver health. An observational study of 237 children and adolescents revealed that higher dairy fat intake and higher levels of certain fatty acids, including C15:0, were associated with lower liver fat levels.

4) Reduced risk of type 2 diabetes. C15:0 promotes glucose uptake into muscle cells and improves insulin sensitivity without affecting insulin-dependent pathways.

5) Cellular health and longevity. Dr. Venn-Watson points to the potential for C15:0 to prevent cell damage and death associated with aging by promoting cell membrane stability and mitochondrial repair.

Unfortunately, industrial agricultural practices have altered the nutritional content of dairy and meat products, reducing the natural levels of C15:0 in these foods. Furthermore, most nutrition authorities currently do not recognize C15:0 as a nutrient. According to Dr. Venn-Watson, research from human, animal, and laboratory studies indicates that most people need 100 to 300 milligrams of C15:0 daily to achieve and maintain healthy blood fatty acid levels. Yogurt, C15:0 content per 3/4 cup (170 grams):

• Whole cow's milk Greek yogurt: 80 to 100 milligrams

• Whole cow's milk yogurt: 70 to 90 milligrams

• Whole goat's milk yogurt: 60 to 70 milligrams

Cheese, C15:0 content per 1 ounce (28 grams):

• Swiss (Emmenthaler): 70 to 90 milligrams

• Parmesan: 70 to 90 milligrams

• Goat's milk: 65 to 85 milligrams

• Cow's milk mozzarella: 50 to 80 milligrams

Milk fats, C15:0 content per 1 tablespoon (14 grams):

• Heavy cream: 50 to 60 milligrams

• Butter: 50 to 60 milligrams

• Cream cheese: 45 to 55 milligrams .--

https://www.mdpi.com/2072-6643/15/21/4607 (2023) .--

https://www.nature.com/articles/s41598-020-64960-y (2020).--

https://www.mdpi.com/2218-1989/14/7/355 (2024).--

https://keto-mojo.com/es/article/c15-fatty-acid-health-benefits/ .---

https://www.sciencedirect.com/science/article/pii/S2211601X15000255?via%3Dihub .---

https://linkinghub.elsevier.com/retrieve/pii/S0022030223002278 .---

Experimental research has shown that C15:0 is an active and beneficial fatty acid with direct pleiotropic activities relevant to halting chronic diseases, particularly with aging. Specifically, C15:0 is a dual peroxisome proliferator-activated receptor α/δ partial agonist, an activator of AMP-activated protein kinase, and a histone deacetylase 6 inhibitor. Additionally, C15:0 has been shown to repair mitochondrial function, improve red blood cell stability, regulate glucose metabolism, and decrease cancer cell proliferation.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9135213/ (2022).—

C15:0 is a recently discovered essential fatty acid that plays a pivotal role in physically strengthening cell membranes and protecting cells from lipid peroxidation. As part of a cellular stability hypothesis, it is proposed that adequate concentrations of C15:0 in cell membranes are necessary to prevent ferroptosis, a recently discovered method of cell death involving lipid peroxidation of cell membrane fatty acids and intracellular iron, which has also been linked to type 2 diabetes, cardiovascular disease, and NAFLD.

Based on numerous studies provided in this review, a definition of C15:0 nutritional deficiency is offered (circulating C15:0 ≤ 0.2% of total fatty acids). A description of the pathophysiology behind this C15:0 nutritional deficiency syndrome (cellular fragility syndrome) is provided, explaining how low C15:0 levels can accelerate the progression of aging-associated diseases, including dysmetabolic iron overload syndrome, type 2 diabetes, cardiovascular disease, and NAFLD. In addition to correcting nutritional deficiencies, there is evidence that optimal circulating C15:0 concentrations (>0.4% to 0.64% of total fatty acids) may support cardiovascular health and longevity over the long term. Continued studies, including clinical trials, will help further test the cellular stability hypothesis and the proposed definition of C15:0 nutritional deficiencies. Given the global declines in dietary C15:0 intake, further studies are needed to better understand the depth and breadth of the cellular fragility syndrome driven by C15:0 deficiency in different human populations and how this syndrome may be contributing to the increase in aging-associated diseases, particularly among younger individuals.

https://www.mdpi.com/2218-1989/14/7/355 (2024).--

Expand full comment
Just steve's avatar

Properly managed soil feeds soil life. Healthy soil life processes carbon, minerals and probably things we haven't even discovered yet to in turn feed properly managed plants. Properly risen plants consumed by properly risen animals, cows producing milk in this case, to contain those necessary needed nutrients to process and produce a complete profile for actual real and healthy milk.

No need for high tech, heavily soaked chemicals or additives to produce just one more thing in a line of pretend food needing massive PR Marketing. Pretend food more than likely also heavily subsidized throughout the Industrial Factory Farm system hiding a higher cost beyond what is seen for such products on the shelf.

Properly managed agriculture addresses in dramatic, substantial ways to clean up, heal nearly every negativity we currently deal with because of the current total disconnect from how Creation actually works.

Expand full comment
Guillermou's avatar

Well said, Just. The soil must be regenerated in a symbiosis between agriculture and livestock. We cannot allow cross-pollination, where pollen from new varieties can reach natural plants and modify their genetics. In addition to cross-pollination during cultivation, there are many other stages of the food chain where contamination from genetically modified organisms can occur, from grain transportation and storage to processing.

Industrial agriculture is degenerating farmland. For example, residue from Bt corn plants after tilling the soil after harvest inhibits its ability to respire (produce carbon dioxide), also reduces mycorrhizal colonization, and seriously alters bacterial populations within the soil ecosystem. This function of the soil is vitally important for regulating plant growth and vitality and for increasing the availability of minerals and nutrients. Regenerative agriculture and livestock farming are a true incentive for the goal of truly holistic, chemical-free "regenerative organic" agriculture. This approach must embrace a more holistic approach that also encompasses the well-being of farmers and animals, a process to which pioneers of the regenerative organic movement Rodale, Steiner, Holmgren, etc., contributed.

What Mother Nature has done for 10,000 years in agriculture and modification through laboratory design are not the same. They ignore human agricultural culture, developed by millions of farmers in thousands of different biogeographic and climatic situations, which has respected natural mechanisms over time, selecting new varieties from populations originating through crossbreeding until the appropriate phenotype is found and stabilized. These processes of adaptation and adjustment of crop characteristics carried out by agricultural communities over the years also permanently test their impacts on human health and the environments where the new varieties are generated. Let's fight for the survival of Mother Nature.

Expand full comment
Just steve's avatar

So important to pay attention to Gui, the cross pollination of GMO stock contaminating our natural plants to then in turn block their genetics. Just my Gut Speaking but, not only are the "We have to do this to feed the world crowd" playing with plants, insects, even peoples Genetic Tree of Life, we have seen years ago how they trespassed into independent farmers rising their own saved seed stock after being contaminated by the promiscuous GMO genes, taken to court and sued for the Bull Spit claim the independent farmer "stole their property the genes." What has the Gut stirred up is this absurd notion lays open a path for these bad birds to claim when 'their genetic property shows up wherever, now it is their property because they own the genetic material. Being as it is has long been precedent Corporations can not patent natural products, the Gut is stirred up with this playing around with little to no way to stop what is unwanted, unnecessary genetic contamination a way to claim as their genes travel throughout Creation, that all will become their Property, can be patented, Owned!

Plants have been shown to have massive amounts of information buried into their genes as compared to Humans and this suggests massive backup systems to reboot after many eons of many types and kinds of experiences of the plants. In what seems as much as a self loathing and a drive for their Transhuman Agenda they are not only attacking Humanity, Plant Life but Life itself.

Another consideration; Legacy Media, Authorities promote Scientist have a Consensus about - fill in the blank. Consensus is not science. Consensus is a process where a committee of those who in traditional settings would have conflicting agendas, use a method we are conditioned to believe is there are only winners and losers. There can be no winners without losers. There are only two choices, winner takes all. Consensus searches for an outcome where possibly a win - win can be found. Example; The town comes into a windfall where it is possible for improvements. One faction wants a new fire station, the other wants a Community Daycare. There isn't enough money to do both. What we usually are given is one wins, the other loses. With a consensus process though after give and take it was decided we build a new smaller firehouse with the ability to expand more later, and use a portion of the windfall on the old firehouse to make a Day Care - a win, win. Consensus is being used in Legacy Media, the Political Body to claim We Are The Experts and We Have Decided Because We Say So. Then call that Consensus. It is not, it is clever word gaming manipulation.

Expand full comment
Guillermou's avatar

Just, his words reflect his experience as a farmer. The toxicity of GMOs is a threat to biodiversity and wildlife, just as it is to humans.

Numerous studies have shown that it is virtually impossible to prevent the dispersal of pollen from GM crops, completely avoiding unwanted pollination of other crops and the contamination of ecosystems. Under certain climatic conditions, pollen can rise to high altitudes and travel great distances, pollinating very distant fields.

Although GM crops occupy a still small percentage of the world's agricultural land, they have already produced alarming contamination of fields, seeds, and even some germplasm banks, becoming a worrying problem. A compilation of testimonies from North American farmers published in 2002 revealed widespread and worrying contamination in the US and Canada. In 2004, a new study revealed that between 50% and 85% of the seeds of conventional corn varieties sold in the US the previous year were contaminated by genetically modified (GM) DNA, and some seed banks had also been contaminated.

Several cases of genetic contamination of organic crops by GM corn have also been detected in Spain.

Ten percent of the exotic species that humans have introduced into the environment have caused significant problems, and in some cases, genuine ecological disasters.

However, it has been proven that GM traits can jump relatively easily to other crops and wild species, spreading throughout the environment with completely unforeseen consequences. The possibility of rapid spread of GM traits to wild species and their persistence has been confirmed in various studies conducted over the last few years. An experiment conducted in France demonstrated the transfer of a transgenic trait (herbicide resistance) from a rapeseed variety to wild relatives and its persistence after four generations.

Moreover, trials with Arabidopsis thaliana showed that the probability of transmitting herbicide resistance to wild relatives was 20 times higher in the case of GM varieties than when this trait had been induced in the plants by conventional mutagenesis, suggesting that transgenes have a greater propensity to escape.

References:

--Friends of the Earth, COAG, Ecologists in Action, and Greenpeace. Coexistence of genetically modified, conventional, and organic crops. A critique of the draft Ministerial Order ordering the publication of recommendations on the coexistence of genetically modified, conventional, and organic crops. March 2004.

Expand full comment