Linoleic acid found in vegetables and seed oils may be the biggest contributor to chronic disease in the Western world. Read the shocking findings here.
A report of great informative content that constitutes a call to health with the good management of fatty acids. Cardiolipin (CL) plays an essential role in the maintenance of mitochondrial ultrastructure and function in multiple cell types. Aberrant CL metabolism has been directly linked to a number of physiologic and developmental abnormalities, including embryonic lethality, cardiomyopathy, immune cell defects, hematopoietic stem cell dysfunction, neuronal dysfunction, and metabolic disorders.
Clinical and experimental studies in human patients and animal models have also provided convincing evidence that abnormal cardiolipin content, acyl chain composition, localization, and oxidation level may be directly related to multiple diseases, including cardiomyopathy. , neuronal dysfunction, immune cell defects and metabolic disorders. The central role of CL in regulating the pathogenesis and progression of these diseases has attracted increasing attention in recent years. CL is crucial for regulating various mitochondrial functions, ranging from respiration and metabolism to apoptosis.
CL may also play an important role in the regulation of mitochondrial metabolism. The mitochondria is not only the powerhouse, but also one of the central organelles of metabolism, participating in numerous metabolic processes, including the citric acid cycle, fatty acid oxidation, amino acid synthesis and degradation, as well as of iron and sulfur groups. It has been shown that CL can interact with several mitochondrial transporter proteins. A 20-25% loss of the amount of CL has been found in ischemic hearts, and interestingly, such a reduction in CL levels seems to precede losses in other phospholipids.
Reduced total CL content and changes in CL species composition have been detected in both aged human hearts and patients with heart failure. CL may also function as a key player in regulating mitochondrial function and structure in immune cells, and consequently also in their fate and cellular fitness. Normal CL biosynthesis has been shown to be essential for hematopoietic stem cell differentiation. CL can regulate the function and survival of β cells. In adipose tissue, lipid metabolism pathways can be significantly activated during cold adaptation, further highlighted by the upregulation of CL, especially newly synthesized CL in brown and beige adipose tissues. Indeed, CL biosynthesis plays an essential role in maintaining energy homeostasis and insulin sensitivity.
Astrocytes become very important during oxidative stress by triggering the inflammatory response by increasing the levels of proinflammatory cytokines such as TNFα, IL-1β, IL-6, IL-18 and COX-2 messenger RNA, whose levels are altered during oxidative stress. inflammatory processes. Astrocytes are also affected upon the release of neurotrophic factors, including GDNF, BDNF. GFAP is involved in the maintenance of cellular cytoarchitecture (CNS), mechanical stability, and synaptic function, properties that are markedly affected by aging. For example, decreased GFAP expression, which reflects astroglial degeneration, has been found in the early stages of many neurodegenerative diseases. Current evidence clearly indicates that neuroinflammation plays an important role in the etiology and development of several neurological disorders, including neurodegenerative diseases such as AD and Parkinson's disease, and psychiatric conditions, including major depression, bipolar disorders, mental disorder, post-traumatic stress and as an effect of prolonged periods of immobilization, as occurs in bedridden patients or hospitalized in intensive care units and that lead to
frank decrease in the functionality and independence of individuals.
Amazing job, definitely going to try to show this to my family as much as I tried to warn otherwise. They did switch to cooking with lard at least half the time or more, but they don't understand amounts, and use olive and (roasted) pumpkin seed oil almost every day as dressings and whatnot.
So if Olive oil and avocado oil is no longer acceptable what do I use for a salad dressing? Do I try to find "real" olive oil? Is MCT Oil ok or not ok?
Dr. Mercola, I have a family member who's a pre-diabetic physician (and statin user) that sent me this link in response to me sharing this article - https://www.hsph.harvard.edu/nutritionsource/2014/11/05/dietary-linoleic-acid-and-risk-of-coronary-heart-disease/ citing "opposing views / controversy to what is shared above" and they don't believe it ... I'm having a difficult time letting it go. Serious question for anyone who has read the Harvard study as it feels difficult to trust anything coming out of Harvard as it relates to big ag / big pharma supported labs and universities, and hopeless to convince the family member of their seed oil fueled dependence on statins, a crummy diet.
Dr. Mercola - have you or anyone ever debunked the Harvard link above? Any help appreciated!
Great Article busting myths of what most people are chronically ill. I am plant based my self as I find it hard to take a life and it had worked well for me. I read all the books that are Pro Meat so I always know both sides of the argument. Although I get the science of the meat side, for me it does not add up as all my markets are perfect (good triglycerides/HDL and Total Cholesterol/HDL as well as perfect blood pressure) and everyone asked me how I look phisicually 36 and no fat on me when im 46 (not ego here just to illustrate that I am not suffering from malnutrition). I have been eating plants (with maybe once a month some local white fish or none at all, mostly because I go to dinner with friends to nice places and get bored of eating just a salad in font of everyone) for 15 years and according to all the pro meat science on nutrition, I should have every chronic disease possible because I supposedly cant get the key vitamins and minerals unless I eat meat. So Although I see both sides of science, even how it has possibly been squed by the Cabal Agenda, my personal experience and that of my kids does not add up to it. Something is missing and no one has been able to give me a satisfactory explanation, although I have my own theories. Just like the Olive Oil is deadly for you, when it has been consumed in the Mediterranean for thousands of years probably and we (I grew up there) have some of the longest life epectancy in the world. Obviously best to eat good quality Virgin Cold Pressed as opposed to heated up in pan. I have followed Dr M for many years now and he always seems to make the same generalisations. So everyone eats crap quality Olive Oil so its bad for you, another one is if you eat plant based you need to eat meat because its better for you as you must be eating processed fake crap meat etc, which in my case is the opposite of what I eat. Anyway, some more clarification on these gray area statements would be appreciated.
yeah I quit eating anything with LA in it.....I now eat MEAT..90% of what I eat is beef......right outta my freezer...the other 10% is fruit and real honey...and I do chug down 2 H2 pills in hot water , naturally Mercola H2 in about 6-8 oz a hot water drop in 2 tablets and swish them around for 10 seconds and Down the hatch.......maybe have a steak for breakfast...with a Egg-cream-honey mix.(eggnog) use 3- egg yokes only.........MMMMMMMM next meal in about 16 hours.....and this is a long lasting meal.....
This only a part chapter from this great book "Invisible Rainbow" and excellent read....Interesting how Radio Frequency Radiation Killed Millions including a Queen But Marconi didn't care...with known scientists and proven medical people stating it is a dangerous act..Proven inventors like Tesla and JG Bose and many more.... Marconi went ahead and eventually killed himself.. but 'Pandora's Box' was opened wide......read a bit of the results >>> http://www.thethirdlevel.info/2021/04/marconi-bees-frequencies-queen.html <<<
Thank you for this important information. Mercola Liposomal Vitamin C has sunflower oil as its liposome. Is this safe? My husband had a heart attack and has several arterial blockages so important to be safe on seed oils.
Wow PremaShakti......I have no idea as I am not a vegan.....in my teen years I was into a vegan type of lifestyle but felt bloated and gassy a lot....not comfortable...and now decades later i know vegan was not my way of life......so I started reading more on Dr Paul Saladino and his medical diet of beef , MEAT and organ meats.....now as I was growing up, my Mother always had a Liver dinner.....and I like Liver and onions......and always felt great the next few days.....well putting 2 to 2 coming up with 4 and realized liver was making me feel good..............so now all I eat is MEAT and Ill eat the organs too
Now I am and Old man 75++and watching eagles and hawks and ravens and owls...and when a hawk attacks an animal the first thing they eat is the Liver and heart,,,,First thing..... even chickens and they will eat each other...first thing they will eat is the Liver and Heart....why?
Well as a vagen you consume a lot of phytic acid.....and Phytic acid is on every seed....one reason why coffee tastes bitter z>> https://www.healthline.com/nutrition/phytic-acid-101 <<< this is the stuff dietricians don't tell and most have no idea what it is.....
I am just learning about the ill effects of seeds and seed oil. I was disappointed reading the label of Dr. Mercola’s nutrition bars full of different seeds and natural flavors specifically the Mitomax Keto. Will you be ridding of these ingredients in your bars soon?
A report of great informative content that constitutes a call to health with the good management of fatty acids. Cardiolipin (CL) plays an essential role in the maintenance of mitochondrial ultrastructure and function in multiple cell types. Aberrant CL metabolism has been directly linked to a number of physiologic and developmental abnormalities, including embryonic lethality, cardiomyopathy, immune cell defects, hematopoietic stem cell dysfunction, neuronal dysfunction, and metabolic disorders.
Clinical and experimental studies in human patients and animal models have also provided convincing evidence that abnormal cardiolipin content, acyl chain composition, localization, and oxidation level may be directly related to multiple diseases, including cardiomyopathy. , neuronal dysfunction, immune cell defects and metabolic disorders. The central role of CL in regulating the pathogenesis and progression of these diseases has attracted increasing attention in recent years. CL is crucial for regulating various mitochondrial functions, ranging from respiration and metabolism to apoptosis.
CL may also play an important role in the regulation of mitochondrial metabolism. The mitochondria is not only the powerhouse, but also one of the central organelles of metabolism, participating in numerous metabolic processes, including the citric acid cycle, fatty acid oxidation, amino acid synthesis and degradation, as well as of iron and sulfur groups. It has been shown that CL can interact with several mitochondrial transporter proteins. A 20-25% loss of the amount of CL has been found in ischemic hearts, and interestingly, such a reduction in CL levels seems to precede losses in other phospholipids.
Reduced total CL content and changes in CL species composition have been detected in both aged human hearts and patients with heart failure. CL may also function as a key player in regulating mitochondrial function and structure in immune cells, and consequently also in their fate and cellular fitness. Normal CL biosynthesis has been shown to be essential for hematopoietic stem cell differentiation. CL can regulate the function and survival of β cells. In adipose tissue, lipid metabolism pathways can be significantly activated during cold adaptation, further highlighted by the upregulation of CL, especially newly synthesized CL in brown and beige adipose tissues. Indeed, CL biosynthesis plays an essential role in maintaining energy homeostasis and insulin sensitivity.
https://www.mdpi.com/2073-4425/13/10/1889 (2022)
Astrocytes become very important during oxidative stress by triggering the inflammatory response by increasing the levels of proinflammatory cytokines such as TNFα, IL-1β, IL-6, IL-18 and COX-2 messenger RNA, whose levels are altered during oxidative stress. inflammatory processes. Astrocytes are also affected upon the release of neurotrophic factors, including GDNF, BDNF. GFAP is involved in the maintenance of cellular cytoarchitecture (CNS), mechanical stability, and synaptic function, properties that are markedly affected by aging. For example, decreased GFAP expression, which reflects astroglial degeneration, has been found in the early stages of many neurodegenerative diseases. Current evidence clearly indicates that neuroinflammation plays an important role in the etiology and development of several neurological disorders, including neurodegenerative diseases such as AD and Parkinson's disease, and psychiatric conditions, including major depression, bipolar disorders, mental disorder, post-traumatic stress and as an effect of prolonged periods of immobilization, as occurs in bedridden patients or hospitalized in intensive care units and that lead to
frank decrease in the functionality and independence of individuals.
https://www.sciencedirect.com/science/article/abs/pii/S0014482723000381 (2023).----
https://neurologia.com/noticia/8354/la-proteina-acidica-fibrilar-glial-(gfap)-podria-convertirse-en-una-potente-herramienta-diagnostica-en-sangre-de-las-fases- initials-of-alzheimer's (2021).---
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6763158/ (2001).---
https://www.cambridge.org/core/journals/the-british-journal-of-psychiatry/article/neuroimaging-findings-in-posttraumatic-stress-disorder/156E2575B0C6B0132B4BCF95302A976B (2002).---
Thank you, Dr. Mercola. Much gratitude to you. May God bless you more abundantly.
Amazing job, definitely going to try to show this to my family as much as I tried to warn otherwise. They did switch to cooking with lard at least half the time or more, but they don't understand amounts, and use olive and (roasted) pumpkin seed oil almost every day as dressings and whatnot.
So if Olive oil and avocado oil is no longer acceptable what do I use for a salad dressing? Do I try to find "real" olive oil? Is MCT Oil ok or not ok?
I make dressing with homemade yogurt. You can use lemon juice on a salad with salt and pepper.
Dr. Mercola, I have a family member who's a pre-diabetic physician (and statin user) that sent me this link in response to me sharing this article - https://www.hsph.harvard.edu/nutritionsource/2014/11/05/dietary-linoleic-acid-and-risk-of-coronary-heart-disease/ citing "opposing views / controversy to what is shared above" and they don't believe it ... I'm having a difficult time letting it go. Serious question for anyone who has read the Harvard study as it feels difficult to trust anything coming out of Harvard as it relates to big ag / big pharma supported labs and universities, and hopeless to convince the family member of their seed oil fueled dependence on statins, a crummy diet.
Dr. Mercola - have you or anyone ever debunked the Harvard link above? Any help appreciated!
Great Article busting myths of what most people are chronically ill. I am plant based my self as I find it hard to take a life and it had worked well for me. I read all the books that are Pro Meat so I always know both sides of the argument. Although I get the science of the meat side, for me it does not add up as all my markets are perfect (good triglycerides/HDL and Total Cholesterol/HDL as well as perfect blood pressure) and everyone asked me how I look phisicually 36 and no fat on me when im 46 (not ego here just to illustrate that I am not suffering from malnutrition). I have been eating plants (with maybe once a month some local white fish or none at all, mostly because I go to dinner with friends to nice places and get bored of eating just a salad in font of everyone) for 15 years and according to all the pro meat science on nutrition, I should have every chronic disease possible because I supposedly cant get the key vitamins and minerals unless I eat meat. So Although I see both sides of science, even how it has possibly been squed by the Cabal Agenda, my personal experience and that of my kids does not add up to it. Something is missing and no one has been able to give me a satisfactory explanation, although I have my own theories. Just like the Olive Oil is deadly for you, when it has been consumed in the Mediterranean for thousands of years probably and we (I grew up there) have some of the longest life epectancy in the world. Obviously best to eat good quality Virgin Cold Pressed as opposed to heated up in pan. I have followed Dr M for many years now and he always seems to make the same generalisations. So everyone eats crap quality Olive Oil so its bad for you, another one is if you eat plant based you need to eat meat because its better for you as you must be eating processed fake crap meat etc, which in my case is the opposite of what I eat. Anyway, some more clarification on these gray area statements would be appreciated.
yeah I quit eating anything with LA in it.....I now eat MEAT..90% of what I eat is beef......right outta my freezer...the other 10% is fruit and real honey...and I do chug down 2 H2 pills in hot water , naturally Mercola H2 in about 6-8 oz a hot water drop in 2 tablets and swish them around for 10 seconds and Down the hatch.......maybe have a steak for breakfast...with a Egg-cream-honey mix.(eggnog) use 3- egg yokes only.........MMMMMMMM next meal in about 16 hours.....and this is a long lasting meal.....
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
This only a part chapter from this great book "Invisible Rainbow" and excellent read....Interesting how Radio Frequency Radiation Killed Millions including a Queen But Marconi didn't care...with known scientists and proven medical people stating it is a dangerous act..Proven inventors like Tesla and JG Bose and many more.... Marconi went ahead and eventually killed himself.. but 'Pandora's Box' was opened wide......read a bit of the results >>> http://www.thethirdlevel.info/2021/04/marconi-bees-frequencies-queen.html <<<
Thank you for this important information. Mercola Liposomal Vitamin C has sunflower oil as its liposome. Is this safe? My husband had a heart attack and has several arterial blockages so important to be safe on seed oils.
Excellent. Can we use carnosine or that less expensive form as protection against APEEL?
Wow PremaShakti......I have no idea as I am not a vegan.....in my teen years I was into a vegan type of lifestyle but felt bloated and gassy a lot....not comfortable...and now decades later i know vegan was not my way of life......so I started reading more on Dr Paul Saladino and his medical diet of beef , MEAT and organ meats.....now as I was growing up, my Mother always had a Liver dinner.....and I like Liver and onions......and always felt great the next few days.....well putting 2 to 2 coming up with 4 and realized liver was making me feel good..............so now all I eat is MEAT and Ill eat the organs too
Now I am and Old man 75++and watching eagles and hawks and ravens and owls...and when a hawk attacks an animal the first thing they eat is the Liver and heart,,,,First thing..... even chickens and they will eat each other...first thing they will eat is the Liver and Heart....why?
Well as a vagen you consume a lot of phytic acid.....and Phytic acid is on every seed....one reason why coffee tastes bitter z>> https://www.healthline.com/nutrition/phytic-acid-101 <<< this is the stuff dietricians don't tell and most have no idea what it is.....
More on dr paul saladino >> https://www.paulsaladinomd.co/about and https://www.paulsaladinomd.co/ <<< good stuff and he used to be a vegan so You might read up on his studies and podcast and his knowlege
And Perma.........I use hot tap water for my H2 pills........swishing artound in 1/2 a coffee mug.......about 300 ml
2 Choir Boys Sing...........for cat lovers >>> https://www.youtube.com/watch?v=ZPdqdqj3ghY
IDK ............but I heard Biden used to Drop Acid a few time IDK i just wondre he he was Dropping Linoleic Acid....Hummmm
From m d old Hippie High up on MyMountain....wondering thru My Caves....sure is nice n cool in here.....a Bit Bit of of n n echo :)
I am just learning about the ill effects of seeds and seed oil. I was disappointed reading the label of Dr. Mercola’s nutrition bars full of different seeds and natural flavors specifically the Mitomax Keto. Will you be ridding of these ingredients in your bars soon?
5G was an overhyped technology bust. Let’s learn our lesson. >>>> https://www.washingtonpost.com/technology/2023/06/13/5g-didnt-matter/