I take higher doses Niacin and notice my skin and vision improves and there is less hair in my brush. Eating enough protein helps with my hair as well.
I have taken suggested dosage of niacinimide but I don’t see the same benefits. Maybe didn’t use long enough. Thankful for the article! 🙏
Several studies have shown that nicotinamide (NAM) could offer benefit in various diseases and pathological conditions. NAM is a neuroprotective mainly due to increasing NAD+ levels. Therefore, NAM could have a therapeutic role against trauma, ischemia and neurodegeneration, in addition to neuropsychological disorders including depression and schizophrenia. Likewise, NAM could be beneficial against diabetes, HIV infection and glaucoma. Regarding cancer, NAM has already demonstrated clinical efficacy against non-melanoma skin cancer and resistance to radiotherapy due to tumor hypoxia. NAM has demonstrated the ability to counteract UV-induced immunosuppression. Topical administration of NAM reduced immunosuppression and suppressed tumor formation in UV-irradiated animal models. There is also evidence for the chemopreventive role of NAM in other types of cancer. A previous study demonstrated that intraperitoneal NAM suppressed breast cancer volume in animal models. Accumulating evidence suggests that NAM plays a role in cancer chemoprevention and therapy. Phase III clinical trials have demonstrated the effectiveness of NAM in chemoprevention in the treatment of head and neck, larynx and urinary bladder cancers, incorporating their results into clinical practice. More references in the link
Mitochondrial dysfunction is caused by poor nutrition. highly processed and pesticide-contaminated diet, load of sugars and additives, vaccines, fluoridated and contaminated water, stress, etc., NAD+ increases mitochondrial energy and its deficiency is an essential factor in chronic diseases and aging.
Individual metabolic processes to produce NAD may be different depending on age, diseases and genetics. The "raw materials" or "building blocks" (metabolic precursors) that the body needs to produce (synthesis) NAD+:
Additional support for mitochondrial function includes acetyl-L-carnitine, nicotinamide, Q10, pyrroloquinoline quinone, vitamin C, choline, NADH, α-lipoic acid, α-ketoglutaric acid, resveratrol, N-acetylcysteine, magnesium, and a multivitamin and quality mineral. In the following link more references:
I take higher doses Niacin and notice my skin and vision improves and there is less hair in my brush. Eating enough protein helps with my hair as well.
I have taken suggested dosage of niacinimide but I don’t see the same benefits. Maybe didn’t use long enough. Thankful for the article! 🙏
What about for people like me with MTHFR? I don’t think my body processes niacinimide well….
Several studies have shown that nicotinamide (NAM) could offer benefit in various diseases and pathological conditions. NAM is a neuroprotective mainly due to increasing NAD+ levels. Therefore, NAM could have a therapeutic role against trauma, ischemia and neurodegeneration, in addition to neuropsychological disorders including depression and schizophrenia. Likewise, NAM could be beneficial against diabetes, HIV infection and glaucoma. Regarding cancer, NAM has already demonstrated clinical efficacy against non-melanoma skin cancer and resistance to radiotherapy due to tumor hypoxia. NAM has demonstrated the ability to counteract UV-induced immunosuppression. Topical administration of NAM reduced immunosuppression and suppressed tumor formation in UV-irradiated animal models. There is also evidence for the chemopreventive role of NAM in other types of cancer. A previous study demonstrated that intraperitoneal NAM suppressed breast cancer volume in animal models. Accumulating evidence suggests that NAM plays a role in cancer chemoprevention and therapy. Phase III clinical trials have demonstrated the effectiveness of NAM in chemoprevention in the treatment of head and neck, larynx and urinary bladder cancers, incorporating their results into clinical practice. More references in the link
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https://www.mdpi.com/2218-273X/10/3/477 (2020)
https://onlinelibrary.wiley.com/doi/abs/10.1002/mc.23673 (2024).---
Mitochondrial dysfunction is caused by poor nutrition. highly processed and pesticide-contaminated diet, load of sugars and additives, vaccines, fluoridated and contaminated water, stress, etc., NAD+ increases mitochondrial energy and its deficiency is an essential factor in chronic diseases and aging.
https://www.liebertpub.com/doi/abs/10.1089/ars.2017.7445 (2018).---
Individual metabolic processes to produce NAD may be different depending on age, diseases and genetics. The "raw materials" or "building blocks" (metabolic precursors) that the body needs to produce (synthesis) NAD+:
1.- Nicotinamide riboside (NR)
2.- Nicotinic acid
3.- Nicotinamide
4.- Nicotinamide mononucleotide (NMN)
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4112140/ (2014)
https://pubmed.ncbi.nlm.nih.gov/19286518/ (2009)
Additional support for mitochondrial function includes acetyl-L-carnitine, nicotinamide, Q10, pyrroloquinoline quinone, vitamin C, choline, NADH, α-lipoic acid, α-ketoglutaric acid, resveratrol, N-acetylcysteine, magnesium, and a multivitamin and quality mineral. In the following link more references:
33 NATURAL WAYS TO IMPROVE MITOCHONDRIAL FUNCTION
https://selfhacked.com/blog/natural-ways-to-improve-mitochondrial-function/ (2022). .---
http://onlinelibrary.wiley.com/doi/10.1111/cns.12655/full (2017).---
https://www.annualreviews.org/doi/abs/10.1146/annurev-pharmtox-010716-104908 (2018).--
https://link.springer.com/book/10.1007%2F978-3-319-73344-9#page=493 (2018).---
I already take a B Complex with 100mg of Niacin, should/can I take additional Niacinamide, say another 50mg at night?