Leaky gut syndrome and gut health issues can lead to histamine intolerance, oxalate intolerance, and salicylate intolerance. The buildup of histamine, oxalate, and salicylate causes increased inflammation, gut health issues, and leaky gut leading to inflammation and health issues. Salicylate intolerance develops very similar to oxalate intolerance. Poor gut health and poor liver function can decrease the body's ability to deal with excess salicylates. The buildup of salicylate and oxalates can trigger histamine intolerance, causing leaky gut syndrome.
In a healthy body, Oxalobacter formigenes and Lactobacillus are there to act as oxalate-degrading bacteria. But if you have compromised gut flora due to a low-nutrient diet, nutrient deficiencies, antibiotic use, genetic mutations, liver or kidney problems, or chronic stress, your body will have a difficult time removing oxalates properly.
Excess oxalates and the body's inability to handle them can lead to mineral malabsorption, inflammation, a compromised immune system, oxidative stress, poor mitochondrial function, cellular and tissue damage, and histamine release. Oxalates can bind to certain minerals, including magnesium, iron, copper, potassium, and calcium, and influence metabolism, mitochondrial function, and inflammation levels. Health problems:---
At least 50% of the total oxalate in the body comes from food. The rest is formed inside the body (metabolic oxalate) from two sources: the breakdown of vitamin C and the metabolism of amino acids and other substances.
Oxalate hyperabsorption is a reality in people with gastrointestinal inflammation, whether obesity, insulin resistance, metabolic syndrome, or another inflammatory disease.
Your body's ability to create oxalates also depends on your genetics and nutritional deficiencies. A diet rich in oxalate is intrinsically deficient in minerals, especially calcium and magnesium. Excess oxalate also generates an additional demand for vitamins B6 and B1, which contributes to creating functional deficiencies of these nutrients.
Bile is essential for the absorption of fats. In a healthy intestine, oxalates bind to calcium forming calcium oxalate and are eventually released through bowel movements. With poor bile formation and excess fat, calcium will bind to fat and your body will end up absorbing too many oxalates.
Additionally, yeasts and molds can also create oxalates. Excessive yeast and mold growth can also cause high oxalate levels. However, mold and yeast can also trigger histamine intolerance and mast cell activation syndrome (MCAS). It can also increase inflammation in the body, lead to poor gut health, and cause leaky gut syndrome. Inflammation and gut problems can further fuel the body's inability to absorb histamines, oxalates, and salicylates.
Natural aids to help you avoid the accumulation of oxalates. -----------
1) Citric acid: Binds to oxalate crystals and weakens them, helping to dissolve deposits in the kidneys and other places.---
2) You can take a quarter teaspoon of sodium or potassium bicarbonate between meals, three times a day. Increases urinary citrate and reduces inflammation.
3) Vitamin group B.--
4) Calcium reduces the formation of kidney stones.---
5) Vitamin B6 has been shown to reduce oxalate production. Also vitamin E, selenium and arginine supplements reduce oxalate damage
6) 6) Lactobacillus acidophilus and Bifidobacterium lactis have enzymes that degrade oxalates..—
7) Increase water intake to help eliminate oxalates.---
To reduce the body's production of oxalate, it is advisable to avoid metabolic stress caused by:
1) The use of polyunsaturated seed oils (soybean, corn, safflower, sunflower, etc., which are used in ultra-processed foods and in restaurant kitchens).--------
2) Excess refined sugars in the diet which increases blood glucose and insulin.
3) Excess calories in general.---------
4) In addition, it is advisable to avoid excess oxalate precursors, such as vitamin C
When calcium is taken with foods rich in oxalates, oxalic acid in the intestine combines with calcium to form insoluble calcium oxalate crystals that are eliminated in the stool. This form of oxalate cannot be absorbed by the body. When calcium is low in the diet, oxalic acid is soluble in the liquid portion of the contents of the intestine (called chyme) and is easily absorbed from the intestine into the bloodstream.
In the genetic disease hyperoxaluria type I and in vitamin B-6 deficiency, there is a deficiency in the enzymatic activity of alanine glyoxylate amino transferase (AGT), which leads to the accumulation of glyoxylic acid. The high glyoxylic acid content can be converted to glycolate by the enzyme GRHPR or to oxalate by the enzyme LDH. Thus, glycolate, glyoxylate and oxalate are the metabolites that are later found elevated in the Organic Acid Test in hyperoxaluria type I and in vitamin B-6 deficiency..---
1) Calcium and magnesium citrate supplements may reduce oxalate absorption in the intestine. Citrate is the preferred form of calcium for reducing oxalate because citrate also inhibits the absorption of oxalate in the intestinal tract..---
2) N-acetyl glucosamine supplements can stimulate the production of the intercellular cement, hyaluronic acid, to reduce pain caused by oxalates.
3) Chondroitin sulfate can prevent the formation of calcium oxalate crystals..----
4) Vitamin B6 is a cofactor of one of the enzymes that breaks down oxalate in the body and has been shown to reduce oxalate production..--
5) Excess fat in the diet can cause elevated oxalate levels if fatty acids are poorly absorbed due to bile salt deficiency. If taurine is low, taurine supplementation may help stimulate the production of bile salts (taurocholic acid), leading to better fatty acid absorption and lower oxalate absorption.--
6) Probiotics can be very useful in breaking down oxalates in the intestine. People with low amounts of oxalate-degrading bacteria are much more susceptible to kidney stones. Both Lactobacillus acidophilus and Bifidobacterium lactis have enzymes that degrade oxalates.--
7) Vitamin E, selenium, and arginine supplements have been shown to reduce oxalate damage.--
8) Increase water intake to help eliminate oxalates.---
OXALATES ARE FOUND IN MANY DIFFERENT EUROPEAN AND ASIAN FOODS -
EFFECTS OF COOKING AND PROCESSING
If plant leaves are boiled before consumption, this allows soluble oxalate to be leached and discarded in the cooking water. This means that cooked foods contain considerably lower levels of soluble oxalates than the original raw plants. Cooking in a wok generally concentrates the oxalate content as much as
The cooking water is removed as steam. However, during cooking, some of the soluble oxalates can combine with free calcium in foods and become insoluble oxalates; these are not absorbed in the digestive tract. The preparation of juices with fruits or vegetables is being promoted as healthy alternatives, this raises even more problems, since they can be prepared from raw vegetable leaves, such as spinach, which contain high levels of oxalates. These juices are not cooked so the concentration of oxalates is not reduced during their preparation. Recently research has shown that the addition of calcium salts to these juices can significantly reduce the soluble oxalate content of the prepared beverage without changing the flavor.
This is the first time I have read through one of your posts. I have a question for you. I think I heard it said in this interview that no probiotic on the market can survive the digestion process to make a difference. Is that true? Did I hear that right? If that is the case then no probiotic is worth any amount of money. That includes VS#3 which is supposed to be almost the gold standard.
Leaky gut syndrome and gut health issues can lead to histamine intolerance, oxalate intolerance, and salicylate intolerance. The buildup of histamine, oxalate, and salicylate causes increased inflammation, gut health issues, and leaky gut leading to inflammation and health issues. Salicylate intolerance develops very similar to oxalate intolerance. Poor gut health and poor liver function can decrease the body's ability to deal with excess salicylates. The buildup of salicylate and oxalates can trigger histamine intolerance, causing leaky gut syndrome.
In a healthy body, Oxalobacter formigenes and Lactobacillus are there to act as oxalate-degrading bacteria. But if you have compromised gut flora due to a low-nutrient diet, nutrient deficiencies, antibiotic use, genetic mutations, liver or kidney problems, or chronic stress, your body will have a difficult time removing oxalates properly.
Excess oxalates and the body's inability to handle them can lead to mineral malabsorption, inflammation, a compromised immune system, oxidative stress, poor mitochondrial function, cellular and tissue damage, and histamine release. Oxalates can bind to certain minerals, including magnesium, iron, copper, potassium, and calcium, and influence metabolism, mitochondrial function, and inflammation levels. Health problems:---
At least 50% of the total oxalate in the body comes from food. The rest is formed inside the body (metabolic oxalate) from two sources: the breakdown of vitamin C and the metabolism of amino acids and other substances.
Oxalate hyperabsorption is a reality in people with gastrointestinal inflammation, whether obesity, insulin resistance, metabolic syndrome, or another inflammatory disease.
Your body's ability to create oxalates also depends on your genetics and nutritional deficiencies. A diet rich in oxalate is intrinsically deficient in minerals, especially calcium and magnesium. Excess oxalate also generates an additional demand for vitamins B6 and B1, which contributes to creating functional deficiencies of these nutrients.
https://www.pkdiet.com/pdf/oxalate%20lists.pdf .----
Exogenous oxalates come from the foods you eat and from gut microbes. Oxalate content table:
https://ucikidneystonecenter.com/wp-content/uploads/2020/06/Oxalate-Content-of-Foods.pdf .---
Bile is essential for the absorption of fats. In a healthy intestine, oxalates bind to calcium forming calcium oxalate and are eventually released through bowel movements. With poor bile formation and excess fat, calcium will bind to fat and your body will end up absorbing too many oxalates.
Additionally, yeasts and molds can also create oxalates. Excessive yeast and mold growth can also cause high oxalate levels. However, mold and yeast can also trigger histamine intolerance and mast cell activation syndrome (MCAS). It can also increase inflammation in the body, lead to poor gut health, and cause leaky gut syndrome. Inflammation and gut problems can further fuel the body's inability to absorb histamines, oxalates, and salicylates.
https://drbeckycampbell.com/oxalates-salicylates-histamine-intolerance/
Natural aids to help you avoid the accumulation of oxalates. -----------
1) Citric acid: Binds to oxalate crystals and weakens them, helping to dissolve deposits in the kidneys and other places.---
2) You can take a quarter teaspoon of sodium or potassium bicarbonate between meals, three times a day. Increases urinary citrate and reduces inflammation.
3) Vitamin group B.--
4) Calcium reduces the formation of kidney stones.---
5) Vitamin B6 has been shown to reduce oxalate production. Also vitamin E, selenium and arginine supplements reduce oxalate damage
6) 6) Lactobacillus acidophilus and Bifidobacterium lactis have enzymes that degrade oxalates..—
7) Increase water intake to help eliminate oxalates.---
To reduce the body's production of oxalate, it is advisable to avoid metabolic stress caused by:
1) The use of polyunsaturated seed oils (soybean, corn, safflower, sunflower, etc., which are used in ultra-processed foods and in restaurant kitchens).--------
2) Excess refined sugars in the diet which increases blood glucose and insulin.
3) Excess calories in general.---------
4) In addition, it is advisable to avoid excess oxalate precursors, such as vitamin C
When calcium is taken with foods rich in oxalates, oxalic acid in the intestine combines with calcium to form insoluble calcium oxalate crystals that are eliminated in the stool. This form of oxalate cannot be absorbed by the body. When calcium is low in the diet, oxalic acid is soluble in the liquid portion of the contents of the intestine (called chyme) and is easily absorbed from the intestine into the bloodstream.
In the genetic disease hyperoxaluria type I and in vitamin B-6 deficiency, there is a deficiency in the enzymatic activity of alanine glyoxylate amino transferase (AGT), which leads to the accumulation of glyoxylic acid. The high glyoxylic acid content can be converted to glycolate by the enzyme GRHPR or to oxalate by the enzyme LDH. Thus, glycolate, glyoxylate and oxalate are the metabolites that are later found elevated in the Organic Acid Test in hyperoxaluria type I and in vitamin B-6 deficiency..---
1) Calcium and magnesium citrate supplements may reduce oxalate absorption in the intestine. Citrate is the preferred form of calcium for reducing oxalate because citrate also inhibits the absorption of oxalate in the intestinal tract..---
2) N-acetyl glucosamine supplements can stimulate the production of the intercellular cement, hyaluronic acid, to reduce pain caused by oxalates.
3) Chondroitin sulfate can prevent the formation of calcium oxalate crystals..----
4) Vitamin B6 is a cofactor of one of the enzymes that breaks down oxalate in the body and has been shown to reduce oxalate production..--
5) Excess fat in the diet can cause elevated oxalate levels if fatty acids are poorly absorbed due to bile salt deficiency. If taurine is low, taurine supplementation may help stimulate the production of bile salts (taurocholic acid), leading to better fatty acid absorption and lower oxalate absorption.--
6) Probiotics can be very useful in breaking down oxalates in the intestine. People with low amounts of oxalate-degrading bacteria are much more susceptible to kidney stones. Both Lactobacillus acidophilus and Bifidobacterium lactis have enzymes that degrade oxalates.--
7) Vitamin E, selenium, and arginine supplements have been shown to reduce oxalate damage.--
8) Increase water intake to help eliminate oxalates.---
https://mosaicdx.com/resource/high-oxalate-a-major-factor-in-tissue-and-blood-vessel-health/ (2022).--
OXALATES ARE FOUND IN MANY DIFFERENT EUROPEAN AND ASIAN FOODS -
EFFECTS OF COOKING AND PROCESSING
If plant leaves are boiled before consumption, this allows soluble oxalate to be leached and discarded in the cooking water. This means that cooked foods contain considerably lower levels of soluble oxalates than the original raw plants. Cooking in a wok generally concentrates the oxalate content as much as
The cooking water is removed as steam. However, during cooking, some of the soluble oxalates can combine with free calcium in foods and become insoluble oxalates; these are not absorbed in the digestive tract. The preparation of juices with fruits or vegetables is being promoted as healthy alternatives, this raises even more problems, since they can be prepared from raw vegetable leaves, such as spinach, which contain high levels of oxalates. These juices are not cooked so the concentration of oxalates is not reduced during their preparation. Recently research has shown that the addition of calcium salts to these juices can significantly reduce the soluble oxalate content of the prepared beverage without changing the flavor.
https://pdfs.semanticscholar.org/4e83/03e83dd331847c8bef9cc6e0046dc75f30dd.pdf (2018)
This is the first time I have read through one of your posts. I have a question for you. I think I heard it said in this interview that no probiotic on the market can survive the digestion process to make a difference. Is that true? Did I hear that right? If that is the case then no probiotic is worth any amount of money. That includes VS#3 which is supposed to be almost the gold standard.