We are in a world where everything seems possible, but it is difficult and dangerous to find a path that makes it possible to shape the plasticity of the mind to achieve cures that now still seem impossible. "Nootropics are a group of substances (natural or pharmaceutical) suggested to improve memory, enhance cognition, support motivation, and boost creative ability," says Matt Angove, ND, a naturopathic doctor based in Centralia, Washington. Also known as “smart drugs,” some research suggests that nootropics can improve aspects of brain function, including thinking, learning, and memory.
Under the influence of psychedelics, the destabilizing emergence of complex dynamics leads to a more fluid and adaptive neural state in a process that is amplified by the plasticity-enhancing effects of psychedelics. This shift manifests as an acute systemic increase in disorder and a possibly longer-lasting increase in complexity affecting both short-term dynamics and long-term plastic processes. Ethologists are well aware of critical periods because they lay the foundation for a creature's behavior. They are finite periods of time, ranging from days to years, in which the brain is especially impressionable and open to learning.
It is during a critical period that songbirds learn to sing and humans learn to speak. There are critical periods for walking, seeing, and hearing, as well as bonding with parents, developing perfect pitch, and assimilating into a culture. Some neuroscientists suspect that there are as many critical periods as there are brain functions. In the end, all critical periods end, and rightly so. After a while, extreme openness becomes inefficient or downright dysfunctional.
Maybe, just maybe, psychedelics are the “master key” to unlocking everything from blindness to stroke to anorexia. Psychedelics such as MDMA (also known as ecstasy), ketamine, and psilocybin (the active ingredient in magic mushrooms) are known to produce mind-altering effects, including hallucinations in some cases. But each compound affects a different biochemical pathway in the brain during the short-term "trip," leaving scientists wondering why so many of these drugs share the ability to alleviate difficult-to-treat conditions in the long term. .
Childhood is a time of learning. During this critical period of development, neural connections are built, strengthened, or eliminated as an individual interacts with the world.
A Johns Hopkins University research team led by Gül Dölen, now at the University of California, Berkeley, found that psychedelic compounds can restore the brain's youthful flexibility and act as "master keys" to reopen so-called critical periods. of enhanced neuronal plasticity.
In addition to rejuvenating neurons' response to oxytocin, the psychedelics examined by Dölen modified the activity of about 65 genes, approximately one-fifth of which impact the regulation and composition of the extracellular matrix, the material that physically cements or consolidates connections. and neural circuits.
We are in a world where everything seems possible, but it is difficult and dangerous to find a path that makes it possible to shape the plasticity of the mind to achieve cures that now still seem impossible. "Nootropics are a group of substances (natural or pharmaceutical) suggested to improve memory, enhance cognition, support motivation, and boost creative ability," says Matt Angove, ND, a naturopathic doctor based in Centralia, Washington. Also known as “smart drugs,” some research suggests that nootropics can improve aspects of brain function, including thinking, learning, and memory.
https://www.forbes.com/health/supplements/best-nootropics/ (2023).—
https://nootropicsexpert.com/best-natural-nootropics/ (2023).--
Under the influence of psychedelics, the destabilizing emergence of complex dynamics leads to a more fluid and adaptive neural state in a process that is amplified by the plasticity-enhancing effects of psychedelics. This shift manifests as an acute systemic increase in disorder and a possibly longer-lasting increase in complexity affecting both short-term dynamics and long-term plastic processes. Ethologists are well aware of critical periods because they lay the foundation for a creature's behavior. They are finite periods of time, ranging from days to years, in which the brain is especially impressionable and open to learning.
It is during a critical period that songbirds learn to sing and humans learn to speak. There are critical periods for walking, seeing, and hearing, as well as bonding with parents, developing perfect pitch, and assimilating into a culture. Some neuroscientists suspect that there are as many critical periods as there are brain functions. In the end, all critical periods end, and rightly so. After a while, extreme openness becomes inefficient or downright dysfunctional.
Maybe, just maybe, psychedelics are the “master key” to unlocking everything from blindness to stroke to anorexia. Psychedelics such as MDMA (also known as ecstasy), ketamine, and psilocybin (the active ingredient in magic mushrooms) are known to produce mind-altering effects, including hallucinations in some cases. But each compound affects a different biochemical pathway in the brain during the short-term "trip," leaving scientists wondering why so many of these drugs share the ability to alleviate difficult-to-treat conditions in the long term. .
Childhood is a time of learning. During this critical period of development, neural connections are built, strengthened, or eliminated as an individual interacts with the world.
A Johns Hopkins University research team led by Gül Dölen, now at the University of California, Berkeley, found that psychedelic compounds can restore the brain's youthful flexibility and act as "master keys" to reopen so-called critical periods. of enhanced neuronal plasticity.
In addition to rejuvenating neurons' response to oxytocin, the psychedelics examined by Dölen modified the activity of about 65 genes, approximately one-fifth of which impact the regulation and composition of the extracellular matrix, the material that physically cements or consolidates connections. and neural circuits.
https://www.mdpi.com/1099-4300/26/1/90 (2024).--
https://www.wired.com/story/the-psychedelic-scientist-who-sends-brains-back-to-childhood/ (2023).--
https://www.brainfacts.org/thinking-sensing-and-behaving/brain-development/2024/psychedelics-can-reopen-periods-of-heightened-brain-plasticity--051524 .(2024).--
https://tim.blog/2023/04/24/gul-dolen-transcript/ (2023).--
https://www.greenprophet.com/2023/06/how-psychedelics-reset-the-brain/ (2023).--
https://www.vox.com/future-perfect/24032884/psychedelics-gul-dolen-critical-period-blindness-stroke (2024).--
https://www.youtube.com/watch?v=8eAo7YfrdHQ Paul Saladino shopping for food at Walmart