As we know, the intestinal microbiome, where billions of microorganisms are grouped, forms a complex ecosystem, and dysbiosis or certain intestinal bacteria are directly or indirectly related to intestinal diseases, metabolic syndromes and neurological disorders. Intestinal bacteria participate in the regulation of host health through the biosynthesis of various essential nutrients, such as amino acids and vitamins, as well as biologically active components such as short-chain fatty acids (SCFAs) such as butyrate by regulating intestinal peristaltic movement, the function of the epithelial barrier and the immune system. These functions exert protective effects against several diseases such as colorectal cancer, inflammatory bowel disease, diabetes and obesity.
This study examined the importance of nutrients, in addition to dietary fiber, in the survival of gut bacteria in highly health-conscious populations. We found that vitamin B1, which is an essential nutrient for humans, had a significant effect on the survival and competence of bacteria in the symbiotic gut microbiota. In particular, sufficient dietary vitamin B1 intake affects the relative abundance of Ruminococcaceae, and these bacteria have been shown to require dietary vitamin B1. An inverse correlation was also discovered between dietary vitamin B1 intake and the appearance of chronic constipation. A possible explanation for this phenomenon is that the consumption of vitamin B1 in the diet is related to the softening of stools and a greater occurrence of colonic peristalsis.
In this review, the current knowledge on the interaction between gut microbiota and B vitamin nutrition is summarized (Figure 2) to infer the consequences of probiotic supplementation, which could be useful to optimize probiotic treatment. B vitamins act as essential micronutrients for humans. The absorption process of multiple dietary B vitamins requires the help of many transporters, which typically occurs in the small intestine (Table 1). At the same time, the intestinal microbiota not only acts as a producer and/or consumer to modify vitamin B supplementation in the intestine (Table 2), but also affects the absorption of vitamin B by altering the physiological or pathological factors of the gastrointestinal tract. (Table 3). As cofactors of multiple enzymes, supplementation with B vitamins can change the diversity, abundance, and functions of the gut microbiota (Table 4) from the first link. These actions on the modulating effects of group B vitamins on the intestinal microbiome, focusing on their potential role as prebiotic candidates in the following link.
As we know, the intestinal microbiome, where billions of microorganisms are grouped, forms a complex ecosystem, and dysbiosis or certain intestinal bacteria are directly or indirectly related to intestinal diseases, metabolic syndromes and neurological disorders. Intestinal bacteria participate in the regulation of host health through the biosynthesis of various essential nutrients, such as amino acids and vitamins, as well as biologically active components such as short-chain fatty acids (SCFAs) such as butyrate by regulating intestinal peristaltic movement, the function of the epithelial barrier and the immune system. These functions exert protective effects against several diseases such as colorectal cancer, inflammatory bowel disease, diabetes and obesity.
This study examined the importance of nutrients, in addition to dietary fiber, in the survival of gut bacteria in highly health-conscious populations. We found that vitamin B1, which is an essential nutrient for humans, had a significant effect on the survival and competence of bacteria in the symbiotic gut microbiota. In particular, sufficient dietary vitamin B1 intake affects the relative abundance of Ruminococcaceae, and these bacteria have been shown to require dietary vitamin B1. An inverse correlation was also discovered between dietary vitamin B1 intake and the appearance of chronic constipation. A possible explanation for this phenomenon is that the consumption of vitamin B1 in the diet is related to the softening of stools and a greater occurrence of colonic peristalsis.
https://www.mdpi.com/2072-6643/14/10/2078 (2022).--
https://www.ncbi.nlm.nih.gov/books/NBK482360/ (2024).--
https://www.sciencedirect.com/science/article/abs/pii/S0304541222003109 (2022).--
https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2024.1380476/full (2024).--
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11100033/ (2024).--
In this review, the current knowledge on the interaction between gut microbiota and B vitamin nutrition is summarized (Figure 2) to infer the consequences of probiotic supplementation, which could be useful to optimize probiotic treatment. B vitamins act as essential micronutrients for humans. The absorption process of multiple dietary B vitamins requires the help of many transporters, which typically occurs in the small intestine (Table 1). At the same time, the intestinal microbiota not only acts as a producer and/or consumer to modify vitamin B supplementation in the intestine (Table 2), but also affects the absorption of vitamin B by altering the physiological or pathological factors of the gastrointestinal tract. (Table 3). As cofactors of multiple enzymes, supplementation with B vitamins can change the diversity, abundance, and functions of the gut microbiota (Table 4) from the first link. These actions on the modulating effects of group B vitamins on the intestinal microbiome, focusing on their potential role as prebiotic candidates in the following link.
https://www.mdpi.com/2076-2607/10/6/1168 (2022).--
https://www.sciencedirect.com/science/article/abs/pii/S0022316623728277 (2024).--