Spermidine is a natural biomolecule that has a broad spectrum of health-enhancing effects, including notable anti-inflammatory effects. It is also a powerful antioxidant and reportedly improves respiratory function. Spermidine has a positive charge at physiological pH that allows its interaction with oppositely charged DNA and RNA. Dietary intake of spermidine reduces the risk of neurodegeneration, metabolic diseases, heart disease and cancer. Additionally, spermidine-induced autophagy slows the rate of cognitive decline due to its ability to remove amyloid beta plaques in the brain. Spermidine supplementation also improves mitochondrial metabolism and translational activity. The anti-cancer properties of spermidine are of particular interest as it is known to reduce cancer-related mortality in humans.
Spermidine specifically interferes with the tumor cell cycle, resulting in inhibition of tumor cell proliferation and suppression of tumor growth. Furthermore, it also triggers autophagy by regulating key oncological pathways. Increased intake of polyamines, such as spermidine, can suppress oncogenesis and slow tumor growth due to its role in anticancer immunosurveillance and regulation of polyamine metabolism.
Spermidine (SPD) decreases with age, and SPD supplementation has been shown to improve or delay several age-related pathologies, including those of the immune system. Among the proposed mechanisms responsible for immune system rejuvenation by SPD are enhanced autophagy, translational activity, and mitochondrial metabolism.
SPD enhances fatty acid oxidation activity by directly binding and activating mitochondrial trifunctional protein. SPD supplementation enhances fatty acid oxidation activity and increases mitochondrial activities and cytotoxic functions of CD8+ T cells to prevent and improve outcomes of age-related immune pathologies including cancer.
Wth???
How odd there are no comments ???
THE TOP SPERMIDINE-RICH FOODS TO INCLUDE ON YOUR MENU REGULARL
Select the right foods according to the recommendations of Dr. Mercola:
https://www.supersmart.com/en/blog/anti-ageing/which-foods-have-the-highest-content-spermidine-s420 .-------
https://purovitalis.com/foods-high-in-spermidine-the-complete-list/ .---
https://spermidinelife.us/blogs/news/foods-high-in-spermidine .----
I find this article mind blowing
Spermidine is a natural biomolecule that has a broad spectrum of health-enhancing effects, including notable anti-inflammatory effects. It is also a powerful antioxidant and reportedly improves respiratory function. Spermidine has a positive charge at physiological pH that allows its interaction with oppositely charged DNA and RNA. Dietary intake of spermidine reduces the risk of neurodegeneration, metabolic diseases, heart disease and cancer. Additionally, spermidine-induced autophagy slows the rate of cognitive decline due to its ability to remove amyloid beta plaques in the brain. Spermidine supplementation also improves mitochondrial metabolism and translational activity. The anti-cancer properties of spermidine are of particular interest as it is known to reduce cancer-related mortality in humans.
Spermidine specifically interferes with the tumor cell cycle, resulting in inhibition of tumor cell proliferation and suppression of tumor growth. Furthermore, it also triggers autophagy by regulating key oncological pathways. Increased intake of polyamines, such as spermidine, can suppress oncogenesis and slow tumor growth due to its role in anticancer immunosurveillance and regulation of polyamine metabolism.
https://www.frontiersin.org/articles/10.3389/fchem.2023.1164477/full (2023)
Spermidine (SPD) decreases with age, and SPD supplementation has been shown to improve or delay several age-related pathologies, including those of the immune system. Among the proposed mechanisms responsible for immune system rejuvenation by SPD are enhanced autophagy, translational activity, and mitochondrial metabolism.
SPD enhances fatty acid oxidation activity by directly binding and activating mitochondrial trifunctional protein. SPD supplementation enhances fatty acid oxidation activity and increases mitochondrial activities and cytotoxic functions of CD8+ T cells to prevent and improve outcomes of age-related immune pathologies including cancer.
https://www.science.org/doi/full/10.1126/science.abj3510 (2023).---
THE TOP SPERMIDINE-RICH FOODS TO INCLUDE ON YOUR REGULAR MENU
https://www.supersmart.com/en/blog/anti-ageing/which-foods-have-the-highest-content-spermidine-s420 .-------
https://purovitalis.com/foods-high-in-spermidine-the-complete-list/ .---
https://spermidinelife.us/blogs/news/foods-high-in-spermidine .----
I used Spermidine wheat germ for a 60 day period to help clear the spike proteins post-covid. Never heard that sperm was a source. 🤔