2 Comments

B12 deficiency is estimated to affect around 40% of older people over 60 years of age, although more recent studies suggest that this figure can be very high, as high as 70% of all older people suffering from diabetes. cognitive or suffering from chronic illnesses. Taking vitamin B-12 with vitamin C can reduce the amount of vitamin B-12 available in the body. To avoid this interaction, take vitamin C two or more hours after taking the vitamin B-12 supplement. https://www.mayoclinic.org/es-es/drugs-supplements-vitamin-b12/art-20363663 (2021),...

Vitamin B12 deficiency can cause: Alzheimer's, dementia, cognitive impairment and loss of memory, multiple sclerosis and other neurological disorders, mental illnesses, cardiovascular diseases, learning or development disorders in children, the disorder of autism spectrum disorder, autoimmune disease and immune dysregulation, intestinal dysbiosis, fat burning and cancer. Between pregnant women, lactating women and small children, the effects of vitamin B12 deficiency can be particularly devastating. https://link.springer.com/article/10.1186/s41936-020-00148-0 (2020).----

https://www.frontiersin.org/articles/10.3389/fnut.2020.00083/full (2020 ).---

https://www.mdpi.com/2227-9032/11/7/958 (2023) https://www.frontiersin.org/articles/10.3389/fnut.2023.1015046/full (2023)

https ://joe.bioscientifica.com/view/journals/joe/256/2/JOE-22-0158.xml (2023)

A system-based search in Searches in PubMed provide some information on the antioxidant potential properties of B12 including: (1) direct elimination of oxygen-reactive species (ROS), particularly superoxide; (2) indirect stimulation of ROS capture through glutination conservation; (3) modulation of the production of cytokines and growth factors to provide protection against oxidative stress induced by the immune system; (4) reduction of oxidative stress induced by homocysteine; and (5) reduction of oxidative stress caused by advanced final glycation products.

B12 can also take a page out of the modulation of immune responses: a collaborative study on patients with Alzheimer's found significantly higher levels of basal interleucine-6 ​​in patients with a low B12 level compared to those with a normal B12 level .

https://www.mdpi.com/2072-6643/11/2/482/htm (2019).---

https://www.mdpi.com/2072-6643/15/12/2734 (2023) .--

https://iksadyayinevi.com/wp-content/uploads/2023/06/MULTIDISCIPLINARY-APPROACH-IN-MEDICAL-SCIENCE-III.pdf#page=176 (2023).--

https://onlinelibrary. wiley.com/doi/abs/10.1002/ana.26673 (2023).---

By the age of 40, people in the United States will be affected by the MTHFR mutation that this related to high homocystic kidney disease. The 25% of the EE population. Ugh. have defective MTHFR genes. 40% of the EE population. Ugh. has a defective MTHFR gene

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630484/ (2019)

Homocystine reduction reduces depression probabilities by approximately 20%. Depression is a manifestation of persistent Covid. https://jamanetwork.com/journals/jamapsychiatry/article-abstract/482884 .----

https://ajp.psychiatryonline.org/doi/full/10.1176/ajp.2007.164.6.861 .-----

https ://onlinelibrary.wiley.com/doi/abs/10.1111/eci.13486 (2021) .-----

https://www.tandfonline.com/doi/abs/10.1080/1028415X.2022.2060642 (2022)

La Vitamin B12 in its active form methylcobalamin creates important effects on the brain that are responsible for many of its benefits. neuro-protection and protection from neurodegenerative diseases. Methylcobalamin is an endogenous vitamin B12 that exhibits anti-inflammatory and anti-apoptotic activities in a variety of diseases. https://www.sciencedirect.com/science/article/pii/S2211124721012079 (2021) .----

https://www.sciencedirect.com/science/article/pii/S1567576921006767 (2021) .---- https://content.iospress.com/articles/journal-of-alzheimers-disease/jad215384 (2022).--

https://jamanetwork.com/journals/jamaneurology/article-abstract/2792228 (2022).-- --

Expand full comment