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In some actions, vitamin D together with K2 has complementary aspects and in others synergistic. The doses of vitamin D and K2 must be balanced. For example, 5000 IU of vitamin D3 (to achieve in the blood the optimal level for health and disease prevention, including cancer prevention, is between 60 ng/mL and 80 ng/mL (150-200 nmol/L)) and 159 to 180 mcg of vitamin K2 (MK-7) per capsule. These articles address the questions you ask.

THE SCIENCE BEHIND TAKING VITAMIN D AND K TOGETHER FOR ENHANCED HEALTH OUTCOMES

https://www.rupahealth.com/post/the-science-behind-taking-vitamin-d-and-k-together-for-enhanced-health-outcomes (2024).---

THE SYNERGISTIC INTERPLAY BETWEEN VITAMINS D AND K FOR BONE AND CARDIOVASCULAR HEALTH: A NARRATIVE REVIEW.-

Current evidence supports the idea that joint supplementation of vitamins D and K may be more effective than consuming either alone for bone and cardiovascular health. As more is discovered about the powerful combination of vitamins D and K. Taken together, animal and human studies suggest that optimal concentrations of vitamin D and vitamin K are beneficial for bone and cardiovascular health, as supported by genetic studies , molecular, cellular and some studies in humans. However, vitamin D and calcium supplementation along with vitamin K deficiency could also induce long-term soft tissue calcification and CVD, particularly in vitamin K antagonist users and other high-risk populations.

https://www.hindawi.com/journals/ije/2017/7454376/ (2017).-

VITAMIN K2 AND D3 HEALTH BENEFITS: WHAT THE SCIENCE SAYS

https://www.traceminerals.com/blogs/post/vitamin-k2-and-d3-health-benefits-what-the-science-says (2023).--

PLAUSIBLE MECHANISMS BEHIND SYNERGISM BETWEEN MAGNESIUM, VITAMIN D AND VITAMIN K IN MANAGEMENT OF TYPE 2 DIABETES.-

https://www.sciencedirect.com/science/article/abs/pii/S0306987723002359 (2024).--

THE POTENTIAL USE OF VITAMIN D3 AND PHYTOCHEMICALS FOR THEIR ANTI-AGING EFFECTS.-

Additionally, vitamin D3 and phytochemicals synergistically contribute to anti-aging by working with aging-related genes. Furthermore, the prevention of aging processes induced by chronic inflammation requires the maintenance of a healthy intestinal microbiota, which is related to daily dietary habits. In this sense, supplementation with vitamin D3 and phytochemicals plays an important role.

https://www.mdpi.com/1422-0067/25/4/2125 (2024).--

A study evaluating the relationship of vitamin D with cancer states that maintaining blood vitamin D levels between 100 and 120 nmol/L can prevent about 58,000 new cases of breast cancer and 49,000 new colorectal cases each year. These intakes can also reduce mortality from breast, colorectal and prostate cancer by half.

Another five-year study showed that an increase in vitamin D levels reduces the risk of breast cancer. Women who took vitamin D and calcium supplements experienced an 18% lower risk of breast cancer. 14

A study of 5,706 people showed that people with vitamin D levels of 87 to 100 nanograms per liter had a 27% lower risk of colorectal cancer. Mainly this risk is lower in women. fifteen

An analysis of 7 studies found that vitamin D can reduce the mortality rate in patients with prostate cancer.

https://hydroniquehydration.com/blogs/news/vitamin-d-six-incredible-benefits-for-a-healthy-life (2023).--

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