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Over 80% of the immune system is located in the intestine. Most chronic diseases can not only be associated with bowel dysfunction, but can be greatly reduced through dietary corrections.

Spore-based probiotics have colonizing habits, are resistant to stomach acid, antibiotics, heat and light.

Spore-based probiotics can:

1) Recondition the intestine by increasing microbial diversity.----

2) They promote the growth of beneficial bacteria.------

3) They remain in the intestine between 21 and 28 days where they use quorum sensing (the exchange of information between individual bacteria within colonies to coordinate the activity of the entire colony) to understand their microbial environment and identify pathogenic and beneficial bacteria.- ---

4) They can destroy harmful intestinal bacteria and produce metabolites that promote the regrowth of useful bacteria.----

5) Its bacterial spores leave your body through feces about 21-28 days after entering and return to their dormant state.-----

Spore-based probiotics have the following benefits:

1) Help the cognitive function of the elderly,------

2) Improvement of leaky gut syndrome by restoring the intestinal environment and rebalancing the microbiota, they can help repair the intestinal lining, fighting inflammation, reduce gas production by balancing the intestinal flora and improve the barrier functions of the immune system.-- ---

3) Improve post-exercise soreness - The spore-based probiotic strain Bacillus coagulans has been studied to aid in the recovery time of sore muscles.-------

4) Decreased incidence of respiratory tract infections – Research studies on spore-based probiotics administered to older adults showed positive effects on the immune system to decrease infections.-------

5) Oral supplementation with spore-based probiotics was associated with a lower incidence of postprandial dietary endotoxins, triglycerides, and disease risk biomarkers.------

6) Improve the gut-brain connection – The gut-brain axis refers to the chemical and physical connections between the gut and the brain. Millions of nerves and neurons travel between the gut and the brain; However, many of these neurotransmitters and other chemicals that affect the brain are produced in the intestine. Studies have found that altering gut bacteria can improve overall brain health. These probiotics have been called ″psychobiotics″ and have been shown to improve cases of stress, depression and anxiety by producing neurochemicals, gamma-aminobutyric acid (GABA), short-chain fatty acids (SCFAs) counteracting the long-lasting effects of chronic psychosocial stress and inflammation. 'Psychobiotics' can influence our mental state through their impact on the hypothalamic-pituitary-adrenal axis (HPA axis).------

https://casadesante.com/es-eu/blogs/probiotics/are-soil-based-probiotics-the-same-as-spore-based-probiotics (2023).------

https://es.youthandearth.com/blogs/blog/what-are-spore-based-probiotics-let-s-dig-in

https://clarissalenherr.com/why-how-to-take-a-probiotic/ .-----

https://www.sciencedirect.com/science/article/pii/S1756464619305675 (2020).--

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561432/ (2020).--

https://www.mdpi.com/2072-6643/15/3/488 (2023).---

https://www.mdpi.com/2673-8007/1/3/32 (2021).---

https://nyaspubs.onlinelibrary.wiley.com/doi/full/10.1111/nyas.14993 (2023).----

https://www.mdpi.com/1422-0067/24/17/13394 (2023).----

https://www.jrtdd.com/index.php/journal/article/view/2017 (2023).---

https://link.springer.com/article/10.1007/s12035-023-03691-3 (2023).-.----

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