Magnesium Protects Against Stroke, Heart Disease and Diabetes
A review involving over 1 million subjects has linked low magnesium with cardiovascular issues, America's No. 1 killer.
STORY AT-A-GLANCE
People who consume the highest magnesium levels have remarkably lower incidences of coronary heart disease, stroke and Type 2 diabetes, a study reveals
Research over several decades pointed to low magnesium as the culprit in atherogenesis and other heart-related issues, but it was ignored while scientists focused on cholesterol and high saturated-fat diets
Studies show that when calcium and magnesium intake aren’t on an even keel, the risk of heart disease increases
While doctors have focused on cholesterol as the problem and prescribed statins for more than 20 years, this hasn’t changed the fact that heart disease is still the No. 1 killer in the U.S.
Editor's Note: This article is a reprint. It was originally published April 10, 2017.
If you're looking for a way to decrease your risk of developing coronary heart disease, stroke and Type 2 diabetes, research has revealed profound results from starting a simple new habit: consuming an extra 100 milligrams (mg) of magnesium via your food on a daily basis.
Researchers at Zhejiang University and Zhengzhou University in China found that more than 1 million people across nine countries who consumed the most magnesium tested out with a 10% lower risk of coronary heart disease, a 12% lower stroke risk and a 26% lower risk of Type 2 diabetes.
Regarding the research, which was published in Biomed Central,1 lead study author Fudi Wang, Ph.D., explains:
"Low levels of magnesium in the body have been associated with a range of diseases, but no conclusive evidence has been put forward on the link between dietary magnesium and health risks.
Our meta-analysis provides the most up-to-date evidence supporting a link between the role of magnesium in food and reducing the risk of disease ... Our findings will be important for informing the public and policy makers on dietary guidelines to reduce magnesium deficiency-related health risks."2
Wang said in a Medical Xpress news release3 that although current guidelines recommend that men take about 300 mg of magnesium a day, and women 270 mg per day, deficiencies in this mineral are still common, affecting anywhere between 1.5% and 15% of the population.
The researchers hope this information serves to not just encourage people to make sure they're getting adequate magnesium, but to prompt policy makers to change dietary guidelines, which could diminish the number of magnesium deficiency-related diseases.
Heart Issues Linked to Low Magnesium, but Science Takes a 'Wrong Turn'
In 2013, the upshot of a "groundbreaking" review covering what was known about cardiovascular disease from as early as 1937 found that low magnesium levels — not high cholesterol or consumption of too much saturated fat — are the leading cause of many aspects of heart disease.
The 10-year review, conducted by research scientist and author Andrea Rosanoff, Ph.D., was based on the earlier research of Dr. Mildred Seelig, who studied the relationship between magnesium and cardiovascular disease for more than 40 years. Seelig noted:
"These numerous studies have found low magnesium to be associated with all known cardiovascular risk factors, such as cholesterol and high blood pressure, arterial plaque build-up (atherogenesis), hardening of the arteries and the calcification of soft tissues.
This means we have been chasing our tails all of these years going after cholesterol and the high saturated-fat diet, when the true culprit was and still is low magnesium."4
As early as 1957, Rosanoff says, it was very clear that low magnesium was "strongly, convincingly, a cause of atherogenesis and the calcification of soft tissues. But this research was widely and immediately ignored as cholesterol and the high saturated-fat diet became the culprits to fight."
The "wrong turn" scientists took when the research was so clear, Rosanoff asserts, created a trajectory in the way heart disease and other cardiovascular issues have been dealt with across the board. This resulted in entire populations failing to balance their magnesium intake with their calcium intake, and it's getting worse.
Studies continue to show that when calcium and magnesium intake aren't on an even keel, Rosanoff asserts, the risk of heart disease increases.
Evidence 'Much Too Compelling to Ignore'
Medical and naturopathic doctor Carolyn Dean, a member of the Nutritional Magnesium Association's Medical Advisory Board, asserts that it's obvious that cholesterol isn't the cause because statins have been the answer doctors have turned to for their patients for two decades, but heart disease is still the No. 1 killer in America.
Although there are many other medical conditions that can be attributed to low magnesium levels, Dean listed six of the most debilitating:
Hypertension (high blood pressure)
Type 2 diabetes
Problems optimizing cholesterol levels
Heart arrhythmia
Angina
Heart attack
Celebrity dietitian Ashley Koff, also a member of Prevention magazine's advisory board, noted that magnesium has rightfully received increased attention as a critical nutrient in relation to optimal health. Further, she believes that correcting levels of magnesium intake recommendations is one of the most critical health issues today.
"There are many challenges to achieving adequate intake of magnesium in the modern diet; thus I consider magnesium part of the essential nutrients to supplement daily and — in light of this review, specifically — crucial to preventing cardiovascular disease across patient populations."5
In a March 2017 study, scientists found that hypertension was inversely associated with magnesium in children living in higher altitude areas of Argentina.6
Another three-month, randomized, double-blind, placebo-controlled study revealed that magnesium supplementation improved the metabolic status of obese and pre-diabetic patients with mild cases of chronic kidney disease.7
What Makes Magnesium Intake so Important?
Dr. Mehmet Oz, host of the nationally syndicated and Emmy Award-winning Dr. Oz Show, as well as vice-chair and professor of surgery at Columbia University, says magnesium is essential for helping regulate metabolism, and it helps lower blood pressure and dilate arteries.
Additionally, Oz asserts, arguably 3 out of every 4 people in the U.S. fail to get the amount of magnesium they need, which means they're magnesium-deficient. While the World Health Organization (WHO) recommends 400 mg to 500 mg of calcium, Dean advises a 1-to-1 balance with magnesium, with calcium consumed through your diet.
Wang's research analyzed data from 40 epidemiological studies from 1999 to 2016, looking at the associations between dietary magnesium and different diseases. All the studies used self-reporting food frequency questionnaires from 24-hour dietary recall to determine magnesium levels, and they varied widely.
Biological, lifestyle, gender and study location factors were also taken into account. Afterward, he explained, the researchers performed a dose-response analysis for the effect of each 100 mg-per-day increase of dietary magnesium.
The conclusion of the study reinforced the study conclusion that increased consumption of magnesium-rich foods could be beneficial for overall health. Wang's press release noted:
"Magnesium is vital for human health and normal biological functions including glucose metabolism, protein production and synthesis of nucleic acids such as DNA. Diet is the main source of magnesium as the element can be found in foods such as spices, nuts, beans, cocoa … and green leafy vegetables."
Magnesium-Rich Foods: How to Naturally Combat Heart-Related Disease
Magnesium is the fourth most abundant mineral in your body, and more than 300 enzymes rely on it to carry out normal muscle and nerve function related to energy, relaxed blood vessels, good teeth and bone formation, and the regulation of insulin and blood sugar levels.8
Magnesium helps your body detox from toxins and helps synthesize glutathione. It also plays a vital role in your body's mitochondrial performance, and in improving your energy level. One very positive aspect of this mineral is that when your body has taken in the optimal amount, it simply flushes the rest away.
Dean, in her book "The Magnesium Miracle," recommends taking 200 mg per day, but parsed out in two or three doses, as it can have a laxative effect. Other scientists recommend taking almost twice that amount, but age and sex are factors to consider. Foods containing magnesium include:
Spinach
Collard greens
Swiss chard
Turnip greens
Broccoli
Kale
Bok choy
Romaine lettuce
Raw cacao
Nuts and seeds
Fruits and berries
Fatty fish (wild-caught Alaskan salmon) and herbs and spices, including chives, coriander, cumin, parsley, mustard seeds, fennel, basil and cloves, also contain high amounts of magnesium, so as you can see, it's easy to include it in your diet.
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New research from scientists at the Australian National University (ANU) Brain and Neuroimaging Laboratory links magnesium status to a healthy, youthful brain as we age.
Researchers say a higher intake of magnesium-rich foods could also help reduce the risk of dementia, which is the second leading cause of death in Australia and the seventh leading cause of death globally.
The study carried out on more than 6,000 cognitively healthy participants in the United Kingdom, aged between 40 and 73, found thought-provoking conclusions.
For example, the site El Debate in its Health and Wellbeing section, states that those who consume more than 550 milligrams of magnesium per day (the normal is 350) have a brain age approximately one year younger when they reach 55 years of age.
"The study shows that a 41% increase in magnesium intake could lead to less age-related brain shrinkage, which is associated with better cognitive function and a lower risk or delay in the onset of dementia in the elderly. old age," said study lead author Khawlah Alateeq of the ANU National Center for Epidemiology and Population Health.
"Since there is no cure for dementia and the development of pharmacological treatments have been unsuccessful for the past 30 years, it's been suggested that greater attention should be directed towards prevention," study co-author Dr Erin Walsh, who is also from ANU, he said.
https://www.anu.edu.au/news/all-news/eating-more-magnesium-each-day-keeps-dementia-at-bay (2023)
https://link.springer.com/article/10.1007/s00394-023-03123-x (2023)
In one study presented, baseline cognitive testing was performed, with the first follow-up tests occurring six weeks later.
Then for 12 weeks, study participants received a randomized daily dose of either placebos or 1,500 to 2,000 milligrams of Mg threonate, depending on their body weight, as the cognitive tests were repeated at six-week intervals and at 12-week intervals. areas of:
1) Executive function----
2) Working memory------
3) Attention----
4) Episodic memory (ability to remember fleeting events)----
Significantly, the most "surprising" finding is not only that MgT improves performance on individual cognitive tests in older adults with cognitive impairment, but that it also serves to reverse brain aging for more than nine years.
Studies also show how increasing magnesium concentrations in cultured brain cells from the hippocampus (where memories are stored and retrieved) increases both synaptic density and brain plasticity. The reasons why this is important are twofold:
• Synaptic density is not only the measure of the structural integrity of brain synapses, but evidence suggests that greater synaptic density results in more efficient cognitive processing.
• Plasticity is a measure of the speed at which synaptic connections can change with new stimuli; It is essentially learning at the cellular level.
https://www.sciencedirect.com/science/article/abs/pii/S1053811916300404 .----
https://pubmed.ncbi.nlm.nih.gov/22016520/.---
https://articulos.mercola.com/sitios/articulos/archivo/2019/05/27/beneficios-cognitivos-del-treonato-