New research from scientists at the Australian National University (ANU) Brain and Neuroimaging Laboratory links magnesium status to a healthy, youthful brain as we age.
Researchers say a higher intake of magnesium-rich foods could also help reduce the risk of dementia, which is the second leading cause of death in Australia and the seventh leading cause of death globally.
The study carried out on more than 6,000 cognitively healthy participants in the United Kingdom, aged between 40 and 73, found thought-provoking conclusions.
For example, the site El Debate in its Health and Wellbeing section, states that those who consume more than 550 milligrams of magnesium per day (the normal is 350) have a brain age approximately one year younger when they reach 55 years of age.
"The study shows that a 41% increase in magnesium intake could lead to less age-related brain shrinkage, which is associated with better cognitive function and a lower risk or delay in the onset of dementia in the elderly. old age," said study lead author Khawlah Alateeq of the ANU National Center for Epidemiology and Population Health.
"Since there is no cure for dementia and the development of pharmacological treatments have been unsuccessful for the past 30 years, it's been suggested that greater attention should be directed towards prevention," study co-author Dr Erin Walsh, who is also from ANU, he said.
In one study presented, baseline cognitive testing was performed, with the first follow-up tests occurring six weeks later.
Then for 12 weeks, study participants received a randomized daily dose of either placebos or 1,500 to 2,000 milligrams of Mg threonate, depending on their body weight, as the cognitive tests were repeated at six-week intervals and at 12-week intervals. areas of:
1) Executive function----
2) Working memory------
3) Attention----
4) Episodic memory (ability to remember fleeting events)----
Significantly, the most "surprising" finding is not only that MgT improves performance on individual cognitive tests in older adults with cognitive impairment, but that it also serves to reverse brain aging for more than nine years.
Studies also show how increasing magnesium concentrations in cultured brain cells from the hippocampus (where memories are stored and retrieved) increases both synaptic density and brain plasticity. The reasons why this is important are twofold:
• Synaptic density is not only the measure of the structural integrity of brain synapses, but evidence suggests that greater synaptic density results in more efficient cognitive processing.
• Plasticity is a measure of the speed at which synaptic connections can change with new stimuli; It is essentially learning at the cellular level.
New research from scientists at the Australian National University (ANU) Brain and Neuroimaging Laboratory links magnesium status to a healthy, youthful brain as we age.
Researchers say a higher intake of magnesium-rich foods could also help reduce the risk of dementia, which is the second leading cause of death in Australia and the seventh leading cause of death globally.
The study carried out on more than 6,000 cognitively healthy participants in the United Kingdom, aged between 40 and 73, found thought-provoking conclusions.
For example, the site El Debate in its Health and Wellbeing section, states that those who consume more than 550 milligrams of magnesium per day (the normal is 350) have a brain age approximately one year younger when they reach 55 years of age.
"The study shows that a 41% increase in magnesium intake could lead to less age-related brain shrinkage, which is associated with better cognitive function and a lower risk or delay in the onset of dementia in the elderly. old age," said study lead author Khawlah Alateeq of the ANU National Center for Epidemiology and Population Health.
"Since there is no cure for dementia and the development of pharmacological treatments have been unsuccessful for the past 30 years, it's been suggested that greater attention should be directed towards prevention," study co-author Dr Erin Walsh, who is also from ANU, he said.
https://www.anu.edu.au/news/all-news/eating-more-magnesium-each-day-keeps-dementia-at-bay (2023)
https://link.springer.com/article/10.1007/s00394-023-03123-x (2023)
In one study presented, baseline cognitive testing was performed, with the first follow-up tests occurring six weeks later.
Then for 12 weeks, study participants received a randomized daily dose of either placebos or 1,500 to 2,000 milligrams of Mg threonate, depending on their body weight, as the cognitive tests were repeated at six-week intervals and at 12-week intervals. areas of:
1) Executive function----
2) Working memory------
3) Attention----
4) Episodic memory (ability to remember fleeting events)----
Significantly, the most "surprising" finding is not only that MgT improves performance on individual cognitive tests in older adults with cognitive impairment, but that it also serves to reverse brain aging for more than nine years.
Studies also show how increasing magnesium concentrations in cultured brain cells from the hippocampus (where memories are stored and retrieved) increases both synaptic density and brain plasticity. The reasons why this is important are twofold:
• Synaptic density is not only the measure of the structural integrity of brain synapses, but evidence suggests that greater synaptic density results in more efficient cognitive processing.
• Plasticity is a measure of the speed at which synaptic connections can change with new stimuli; It is essentially learning at the cellular level.
https://www.sciencedirect.com/science/article/abs/pii/S1053811916300404 .----
https://pubmed.ncbi.nlm.nih.gov/22016520/.---
https://articulos.mercola.com/sitios/articulos/archivo/2019/05/27/beneficios-cognitivos-del-treonato-