Cardiovascular diseases rank first among the diseases that cause the most deaths in the world, responsible for 40.6% of total deaths in the world.
Dr. Mark, who emphasized the need to build on the seven pillars of health, namely nutrition, sleep, stress management, movement, genetics, hormones avoiding metabolic diseases.
Dr. Mark, who has a full-time wellness-based medical practice in Tulsa, Oklahoma, along with his wife, Dr. Michele, said stress is one of humanity's most obvious killers right now and many don't understand the idea of being stressed.
“Many people end up with hypertension. Sometimes they end up with high blood sugar which can eventually result in low blood sugar due to a sort of adrenal gland shock. The adrenal glands simply can't keep up. So stress is hugely important today,” said Dr. Mark, adding that it is important to define stress appropriately and recognize what the inappropriate definition of stress is.
Multiple reports appear to support the belief that acute psychological stress can precipitate myocardial dysfunction, infarction, arrhythmia, and cardiac death. Activation of cardiac sympathetic outflow and inhibition of cardiac vagal are important mediating mechanisms. Acute stress causes a high amount of catecholamines to be secreted into the blood. These hormones can cause many changes in the body, such as tachycardia, high blood pressure, coronary vasoconstriction, and/or stress cardiomyopathy. Chronic psychological stress is associated with an increased risk of heart disease. With an increase in the level of anxiety, there is a change in the activity of the sympathetic-adrenal, hypothalamic-pituitary-adrenal and renin-angiotensin-aldosterone systems. Furthermore, it is naturally accompanied by changes in carbohydrate, protein and lipid metabolism, procoagulant changes in hemostasis and impairment of vascular endothelial function. All these disorders can lead to increased progression of atherosclerosis, increased coronary vascular tone, increased instability of atherosclerotic plaques, tendency to thrombosis and contribute to the aggravation of the course of coronary heart disease. When we experience constant stress, our amygdala sends signals to the bone marrow to produce more white blood cells, which causes leukocytosis. This in turn causes the arteries to become inflamed and can cause some cardiovascular problems and others as I mentioned before: Heart attacks, angina and stroke.
Also, a team of scientists from McMaster University in Ontario (Canada) has studied the link between the use of antidepressants and the risk of mortality, through a meta-analysis of existing research from several medical databases, looking for a link between mortality and the use of antidepressants. The analysis included 16 studies, with approximately 375,000 participants.
They extracted data on cardiovascular disease, cardiovascular risk and the type of antidepressants taken. They then used a mixed-effects model to conduct their meta-analysis, controlling for depression and other illnesses.
The results revealed that, in the general population, people who took antidepressants had a 33% higher risk of dying prematurely than people who did not take these drugs. Additionally, antidepressant users were 14% more likely to have an adverse cardiovascular event, such as a heart attack.
Cardiovascular diseases rank first among the diseases that cause the most deaths in the world, responsible for 40.6% of total deaths in the world.
Dr. Mark, who emphasized the need to build on the seven pillars of health, namely nutrition, sleep, stress management, movement, genetics, hormones avoiding metabolic diseases.
Dr. Mark, who has a full-time wellness-based medical practice in Tulsa, Oklahoma, along with his wife, Dr. Michele, said stress is one of humanity's most obvious killers right now and many don't understand the idea of being stressed.
“Many people end up with hypertension. Sometimes they end up with high blood sugar which can eventually result in low blood sugar due to a sort of adrenal gland shock. The adrenal glands simply can't keep up. So stress is hugely important today,” said Dr. Mark, adding that it is important to define stress appropriately and recognize what the inappropriate definition of stress is.
Multiple reports appear to support the belief that acute psychological stress can precipitate myocardial dysfunction, infarction, arrhythmia, and cardiac death. Activation of cardiac sympathetic outflow and inhibition of cardiac vagal are important mediating mechanisms. Acute stress causes a high amount of catecholamines to be secreted into the blood. These hormones can cause many changes in the body, such as tachycardia, high blood pressure, coronary vasoconstriction, and/or stress cardiomyopathy. Chronic psychological stress is associated with an increased risk of heart disease. With an increase in the level of anxiety, there is a change in the activity of the sympathetic-adrenal, hypothalamic-pituitary-adrenal and renin-angiotensin-aldosterone systems. Furthermore, it is naturally accompanied by changes in carbohydrate, protein and lipid metabolism, procoagulant changes in hemostasis and impairment of vascular endothelial function. All these disorders can lead to increased progression of atherosclerosis, increased coronary vascular tone, increased instability of atherosclerotic plaques, tendency to thrombosis and contribute to the aggravation of the course of coronary heart disease. When we experience constant stress, our amygdala sends signals to the bone marrow to produce more white blood cells, which causes leukocytosis. This in turn causes the arteries to become inflamed and can cause some cardiovascular problems and others as I mentioned before: Heart attacks, angina and stroke.
Also, a team of scientists from McMaster University in Ontario (Canada) has studied the link between the use of antidepressants and the risk of mortality, through a meta-analysis of existing research from several medical databases, looking for a link between mortality and the use of antidepressants. The analysis included 16 studies, with approximately 375,000 participants.
They extracted data on cardiovascular disease, cardiovascular risk and the type of antidepressants taken. They then used a mixed-effects model to conduct their meta-analysis, controlling for depression and other illnesses.
The results revealed that, in the general population, people who took antidepressants had a 33% higher risk of dying prematurely than people who did not take these drugs. Additionally, antidepressant users were 14% more likely to have an adverse cardiovascular event, such as a heart attack.
https://www.brighteon.com/506133ec-febd-4afc-98cb-493b04011917 .---
https://www.ctvnews.ca/health/antidepressant-use-linked-to-higher-risk-of-premature-death-study-1.3594717?cache=yesclipId104062%3FclipId%3D68597 .---
https://www.medicalnewstoday.com/articles/319462 .----
https://www.sciencedirect.com/science/article/pii/S0002934322001371 (2022).---
https://peerianjournal.com/index.php/tpj/article/view/324 (2022).----
https://www.sciencedirect.com/science/article/abs/pii/S1566070221001557.(2022)
https://www.opastpublishers.com/open-access-articles/the-role-of-stress-in-the-development-of-cardiovascular-diseases.pdf (2023)